1999
Upper Airway Resistance Syndrome: Effect of Nasal Dilation, Sleep Stage, and Sleep Position
Bahammam A, Tate R, Manfreda J, Kryger M. Upper Airway Resistance Syndrome: Effect of Nasal Dilation, Sleep Stage, and Sleep Position. Sleep 1999, 22: 592-598. PMID: 10450594, DOI: 10.1093/sleep/22.5.592.Peer-Reviewed Original ResearchConceptsUpper airway resistance syndromeStage 1 sleepSleep positionNasal dilationDesaturation timeSleep architectureExternal nasal dilationArousal indexCardiorespiratory parametersSleep stagesNREM sleepNasal cross-sectional areaExternal nasal dilatorSlow-wave sleepObstructive sleepAirway collapsibilityConsecutive patientsNasal dilatorNasal obstructionResistance syndromeSupine positionIntrapharyngeal pressureIndirect markerWave sleepCrossover design
1992
The importance of nasal resistance in obstructive sleep apnea syndrome.
Kerr P, Millar T, Buckle P, Kryger M. The importance of nasal resistance in obstructive sleep apnea syndrome. Journal Of Otolaryngology 1992, 21: 189-95. PMID: 1404570.Peer-Reviewed Original ResearchConceptsObstructive sleep apnea syndromeUpper airway collapseSleep apnea syndromeNasal resistanceOSAS patientsApnea syndromeAirway collapseAmount of apneaArousals/hourChronic nasal obstructionNasal airflow resistanceBaseline data collectionNocturnal oxygenationOSAS populationTopical vasoconstrictorOSAS severityNasal obstructionClinical evidenceNocturnal polysomnographyPSG studiesSubjective improvementPosterior rhinomanometryElevated nasal resistanceConditions of baselineSleep architecture
1985
Sleep and Respiration: A Postscript
Kryger M, White D, Zwillich C, Robinson R, Guilleminault C. Sleep and Respiration: A Postscript. Clinics In Chest Medicine 1985, 6: 713-718. PMID: 3853480, DOI: 10.1016/s0272-5231(21)00407-x.Chapters
1981
Upper Airway Obstruction
Acres J, Kryger M. Upper Airway Obstruction. CHEST Journal 1981, 80: 207-211. PMID: 7249767, DOI: 10.1378/chest.80.2.207.Peer-Reviewed Original Research
1976
Depression of Hypoxic Ventilatory Response by Nitrous Oxide
Yacoub O, Doell D, Kryger M, Anthonisen N. Depression of Hypoxic Ventilatory Response by Nitrous Oxide. Anesthesiology 1976, 45: 385-389. PMID: 973689, DOI: 10.1097/00000542-197610000-00006.Peer-Reviewed Original ResearchEffect of Meperidine on Occlusion Pressure Responses to Hypercapnia and Hypoxia with and without External Inspiratory Resistance1–3
Kryger M, Yacoub O, Dosman J, Macklem P, Anthonisen N. Effect of Meperidine on Occlusion Pressure Responses to Hypercapnia and Hypoxia with and without External Inspiratory Resistance1–3. American Journal Of Respiratory And Critical Care Medicine 1976, 114: 333-40. PMID: 973724, DOI: 10.1164/arrd.1976.114.2.333.Peer-Reviewed Original ResearchConceptsInspiratory resistanceNormal subjectsOcclusion pressure responsesInspiratory motor outputEffect of meperidineOral meperidineVentilatory responseAcute increaseInspiratory effortClosed airwayMeperidineHypercapniaProgressive hypoxiaMotor outputMore depressionHypoxiaHypoxic responsePressure responseP0.1Combination of resistanceSubjectsResponseAirwayDiagnosis of obstruction of the upper and central airways
Kryger M, Bode F, Antic R, Anthonisen N. Diagnosis of obstruction of the upper and central airways. The American Journal Of Medicine 1976, 61: 85-93. PMID: 779469, DOI: 10.1016/0002-9343(76)90048-6.Peer-Reviewed Original ResearchMeSH KeywordsAirway ObstructionAirway ResistanceApneaBronchiectasisDiagnosis, DifferentialFemaleForced Expiratory VolumeHumansMaleMiddle AgedObesityPulmonary Heart DiseasePulmonary VentilationRadiographyResidual VolumeRespiratory System AbnormalitiesSleep Wake DisordersTracheal DiseasesTracheal NeoplasmsVital CapacityConceptsUpper airway obstructionAirway obstructionSleep deprivation syndromeFlow-volume loopsDiagnosis of obstructionMethods of diagnosisSuch patientsPhysical examinationUpper airwayCentral airwaysCorrect diagnosisDeprivation syndromePhysiologic testsCharacteristic historyObstructionPatientsDiagnosisAirwayInstructive caseSyndromeSleep
1975
Effect of inspiratory resistance on occlusion pressure in hypoxia and hypercapnia
Kryger M, Yacoub O, Anthonisen N. Effect of inspiratory resistance on occlusion pressure in hypoxia and hypercapnia. Respiratory Physiology & Neurobiology 1975, 24: 241-248. PMID: 1188196, DOI: 10.1016/0034-5687(75)90016-x.Peer-Reviewed Original ResearchMeSH KeywordsAdultAirway ResistanceFemaleHumansHypercapniaHypoxiaMalePulmonary VentilationRespiration