2007
Effect of Ramelteon, a selective MT1/MT2-receptor agonist, on respiration during sleep in mild to moderate COPD
Kryger M, Wang-Weigand S, Zhang J, Roth T. Effect of Ramelteon, a selective MT1/MT2-receptor agonist, on respiration during sleep in mild to moderate COPD. Sleep And Breathing 2007, 12: 243-250. PMID: 18060441, DOI: 10.1007/s11325-007-0156-4.Peer-Reviewed Original ResearchConceptsModerate chronic obstructive pulmonary diseaseChronic obstructive pulmonary diseaseAbnormal breathing eventsSelective MT1/MT2 receptor agonistMT1/MT2 receptor agonistMean apnea-hypopnea indexBreathing eventsEffects of ramelteonMT2 receptor agonistSingle bedtime doseApnea-hypopnea indexObstructive pulmonary diseaseNumber of awakeningsTotal sleep timeMelatonin receptor agonistBedtime dosePlacebo groupAdverse eventsPulmonary diseaseCrossover studyPhysical examinationReceptor agonistSleep efficiencySleep durationSleep time
1976
Diagnosis of obstruction of the upper and central airways
Kryger M, Bode F, Antic R, Anthonisen N. Diagnosis of obstruction of the upper and central airways. The American Journal Of Medicine 1976, 61: 85-93. PMID: 779469, DOI: 10.1016/0002-9343(76)90048-6.Peer-Reviewed Original ResearchMeSH KeywordsAirway ObstructionAirway ResistanceApneaBronchiectasisDiagnosis, DifferentialFemaleForced Expiratory VolumeHumansMaleMiddle AgedObesityPulmonary Heart DiseasePulmonary VentilationRadiographyResidual VolumeRespiratory System AbnormalitiesSleep Wake DisordersTracheal DiseasesTracheal NeoplasmsVital CapacityConceptsUpper airway obstructionAirway obstructionSleep deprivation syndromeFlow-volume loopsDiagnosis of obstructionMethods of diagnosisSuch patientsPhysical examinationUpper airwayCentral airwaysCorrect diagnosisDeprivation syndromePhysiologic testsCharacteristic historyObstructionPatientsDiagnosisAirwayInstructive caseSyndromeSleep