2023
Transplantid.net: A Pilot Crowdsourced, Living, Online Library of Resources for the Teaching and Practice of Transplant Infectious Diseases
Puius Y, Azar M, Tsai H, Vergidis P, Harris C, Anjan S, Barros N, Belga S, Chuang S, Czeresnia J, Goel S, Ince D, Luk A, Majeed A, Multani A, Obeid K, Swaminathan N. Transplantid.net: A Pilot Crowdsourced, Living, Online Library of Resources for the Teaching and Practice of Transplant Infectious Diseases. Open Forum Infectious Diseases 2023, 10: ofad081. PMID: 36861087, PMCID: PMC9969731, DOI: 10.1093/ofid/ofad081.Peer-Reviewed Original Research
2022
Antiviral Treatment of Coronavirus Disease-2019 Pneumonia
Radcliffe C, Malinis M, Azar M. Antiviral Treatment of Coronavirus Disease-2019 Pneumonia. Clinics In Chest Medicine 2022, 44: 279-297. PMID: 37085220, PMCID: PMC9701636, DOI: 10.1016/j.ccm.2022.11.008.Peer-Reviewed Original ResearchConceptsAcute respiratory syndrome coronavirus 2 infectionSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infectionSyndrome coronavirus 2 infectionCoronavirus diseaseCoronavirus 2 infectionDirect acting antiviralsAdditional clinical trialsReal-world studyCOVID-19Acting antiviralsAntiviral treatmentTherapeutic optionsAvailable therapiesClinical trialsDisease progressionInpatient treatmentHigh riskEarly pandemicMonoclonal antibodiesDiseaseTreatmentMorbidityPandemicPneumoniaOutpatientsA consensus conference to define the utility of advanced infectious disease diagnostics in solid organ transplant recipients
Azar MM, Turbett S, Gaston D, Gitman M, Razonable R, Koo S, Hanson K, Kotton C, Silveira F, Banach DB, Basu SS, Bhaskaran A, Danziger-Isakov L, Bard JD, Gandhi R, Hanisch B, John TM, John A, Letourneau AR, Luong M, Maron G, Miller S, Prinzi A, Schwartz I, Simner P, Kumar D, Group O. A consensus conference to define the utility of advanced infectious disease diagnostics in solid organ transplant recipients. American Journal Of Transplantation 2022, 22: 3150-3169. PMID: 35822346, DOI: 10.1111/ajt.17147.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsOrgan transplant recipientsTransplant recipientsConsensus conferenceSolid organ transplant recipientsInfectious diseasesSetting of transplantationInfectious disease diagnosticsTransplant infectious diseasesHigh-quality evidenceEvidence-based recommendationsMultiplex molecular assaysNext-generation sequencing assayDiagnostic stewardshipConsensus statementUnmet needMass spectrometry-based assayClinical useRecipientsClinical microbiologyMolecular assaysAmerican SocietyTransplantationFinancial barriersDiseaseSequencing assays
2021
Emerging Diagnostics for Transplant Infectious Diseases
Azar M, Gaston D, Malinis M. Emerging Diagnostics for Transplant Infectious Diseases. 2021, 1535-1576. DOI: 10.1007/978-3-030-25869-6_69.Peer-Reviewed Original ResearchTransplant infectious diseasesInfectious diseasesPolymerase chain reaction panelHematopoietic stem cell transplantationCommunity-acquired infectionsStem cell transplantationMultidrug-resistant organismsTest performance characteristicsTransplant patientsUncommon pathogenCell transplantationSerious infectionsPatient outcomesClinical impactDiagnostic modalitiesSolid organsMolecular testingClinical specimensPatientsDiseaseDiagnostic advantageInfectionResistance detectionDiagnostic methodsDiagnostic capabilities
2020
Emerging Diagnostics for Transplant Infectious Diseases
Azar M, Gaston D, Malinis M. Emerging Diagnostics for Transplant Infectious Diseases. 2020, 1-44. DOI: 10.1007/978-3-030-01751-4_69-1.Peer-Reviewed Original ResearchTransplant infectious diseasesInfectious diseasesPolymerase chain reaction panelHematopoietic stem cell transplantationCommunity-acquired infectionsStem cell transplantationMultidrug-resistant organismsTest performance characteristicsTransplant patientsUncommon pathogenCell transplantationSerious infectionsPatient outcomesClinical impactDiagnostic modalitiesSolid organsMolecular testingClinical specimensPatientsDiseaseDiagnostic advantageInfectionResistance detectionDiagnostic methodsDiagnostic capabilitiesCurrent Concepts in the Epidemiology, Diagnosis, and Management of Histoplasmosis Syndromes
Azar MM, Loyd JL, Relich RF, Wheat LJ, Hage CA. Current Concepts in the Epidemiology, Diagnosis, and Management of Histoplasmosis Syndromes. Seminars In Respiratory And Critical Care Medicine 2020, 41: 013-030. PMID: 32000281, DOI: 10.1055/s-0039-1698429.Peer-Reviewed Original ResearchConceptsDisseminated diseaseCurrent evidence-based approachesProgressive disseminated diseaseCommon clinical presentationCommunity-acquired pneumoniaChronic pulmonary diseaseSelf-limiting diseaseLiposomal amphotericin BManagement of histoplasmosisEvidence-based approachHistoplasmosis syndromeImmunocompetent patientsPulmonary diseaseClinical presentationCrohn's diseasePreferred agentClinical manifestationsCommon conditionMilder casesAmphotericin BHistoplasmosisAmphotericin B.DiseaseEpidemiologyGlobal disease
2017
Clinical Perspectives in the Diagnosis and Management of Histoplasmosis
Azar MM, Hage CA. Clinical Perspectives in the Diagnosis and Management of Histoplasmosis. Clinics In Chest Medicine 2017, 38: 403-415. PMID: 28797485, DOI: 10.1016/j.ccm.2017.04.004.BooksConceptsAcute pulmonary histoplasmosisDrug of choiceManagement of histoplasmosisDisseminated presentationPulmonary histoplasmosisMild diseaseClinical spectrumDimorphic fungus Histoplasma capsulatumHistoplasmosisAmphotericin BFungus Histoplasma capsulatumClinical perspectiveDiseaseHistoplasma capsulatumMultipronged approachNumber of travelersDiagnosisPatientsTherapyItraconazoleSeverity
2016
Disseminated Histoplasmosis with Skin Lesions and Osteomyelitis in a Patient from the Philippines.
Azar MM, Malinis MF. Disseminated Histoplasmosis with Skin Lesions and Osteomyelitis in a Patient from the Philippines. American Journal Of Tropical Medicine And Hygiene 2016, 95: 70-4. PMID: 26976880, PMCID: PMC4944712, DOI: 10.4269/ajtmh.16-0063.Peer-Reviewed Case Reports and Technical NotesConceptsBone involvementDisseminated histoplasmosisFoot woundsPapular rashProtean manifestationsFinal diagnosisUnusual manifestationSkin lesionsDimorphic fungus Histoplasma capsulatumHistoplasmosisFungus Histoplasma capsulatumHistoplasma capsulatumDiseaseManifestationsRashOsteomyelitisPatientsLesionsDiagnosisHistoplasmosis
Wheat LJ, Azar MM, Bahr NC, Spec A, Relich RF, Hage C. Histoplasmosis. Infectious Disease Clinics Of North America 2016, 30: 207-227. PMID: 26897068, DOI: 10.1016/j.idc.2015.10.009.Books
2015
Blastomycosis in Indiana Clinical and Epidemiologic Patterns of Disease Gleaned from a Multicenter Retrospective Study
Azar MM, Assi R, Relich RF, Schmitt BH, Norris S, Wheat LJ, Hage CA. Blastomycosis in Indiana Clinical and Epidemiologic Patterns of Disease Gleaned from a Multicenter Retrospective Study. CHEST Journal 2015, 148: 1276-1284. PMID: 26020566, DOI: 10.1378/chest.15-0289.Peer-Reviewed Original ResearchConceptsDiabetes mellitusEpidemiologic patternsIncidence of blastomycosisMulticenter retrospective studyCases of blastomycosisMultilobar pneumoniaICU admissionExtrapulmonary diseaseRetrospective studyMean ageIncidence rateFungal antigensEndemic areasLarge seriesAmphotericin BBlastomycosisTotal mortalityIncidenceMellitusPneumoniaSignificant increaseDiseaseIndiana ClinicalARDSImmunosuppressionToscana Virus Encephalitis in a Traveler Returning to the United States
Howell BA, Azar MM, Landry ML, Shaw AC. Toscana Virus Encephalitis in a Traveler Returning to the United States. Journal Of Clinical Microbiology 2015, 53: 1445-1447. PMID: 25673791, PMCID: PMC4365192, DOI: 10.1128/jcm.03498-14.Peer-Reviewed Case Reports and Technical Notes