2001
Selective cyclooxygenase-2 inhibitors: a pattern of nephrotoxicity similar to traditional nonsteroidal anti-inflammatory drugs
Perazella M, Tray K. Selective cyclooxygenase-2 inhibitors: a pattern of nephrotoxicity similar to traditional nonsteroidal anti-inflammatory drugs. The American Journal Of Medicine 2001, 111: 64-67. PMID: 11448662, DOI: 10.1016/s0002-9343(01)00757-4.Peer-Reviewed Original ResearchCOX-2 Inhibitors and the Kidney
Perazella M. COX-2 Inhibitors and the Kidney. Hospital Practice 2001, 36: 43-56. PMID: 11263799, DOI: 10.3810/hp.2001.03.230.Peer-Reviewed Original Research
1999
Midodrine and cool dialysate are effective therapies for symptomatic intradialytic hypotension
Cruz D, Mahnensmith R, Brickel H, Perazella M. Midodrine and cool dialysate are effective therapies for symptomatic intradialytic hypotension. American Journal Of Kidney Diseases 1999, 33: 920-926. PMID: 10213650, DOI: 10.1016/s0272-6386(99)70427-0.Peer-Reviewed Original ResearchConceptsSymptomatic intradialytic hypotensionPost-HD blood pressuresIntradialytic blood pressureIntradialytic hypotensionBlood pressureEffective therapyLaboratory valuesCombination therapy phaseConsecutive HD treatmentsProspective crossover studyBlood pressure measurementsKt/VVolume of salineControl phaseAlpha1 agonistHypotensive symptomsMorbid complicationCrossover studyUseful therapyProspective studyNursing interventionsHD treatmentMidodrineTreatment phaseTherapy phase
1998
Acute Renal Failure and Intravenous Immune Globulin
Perazella M, Cayco A. Acute Renal Failure and Intravenous Immune Globulin. American Journal Of Therapeutics 1998, 5: 399-404. PMID: 10099084, DOI: 10.1097/00045391-199811000-00008.Peer-Reviewed Original ResearchMeSH KeywordsAcute Kidney InjuryAdultAgedAged, 80 and overHumansImmunoglobulins, IntravenousMiddle AgedSucroseConceptsAcute renal failureRenal failureRenal insufficiencyIntravenous immune globulin therapyImmune globulin therapyChronic renal insufficiencyIntravenous immune globulinAcute renal insufficiencyRenal replacement therapyVariety of complicationsGlobulin therapyIVIG infusionIVIG therapyMaintenance dialysisRenal impairmentImmune globulinIVIG preparationsReplacement therapyDrug trialsNumber of casesClinical disordersOlder agePrecise causeTherapyAdverse effects
1997
Intradialytic hypotension: Is midodrine beneficial in symptomatic hemodialysis patients?
Cruz D, Mahnensmith R, Perazella M. Intradialytic hypotension: Is midodrine beneficial in symptomatic hemodialysis patients? American Journal Of Kidney Diseases 1997, 30: 772-779. PMID: 9398120, DOI: 10.1016/s0272-6386(97)90081-0.Peer-Reviewed Original ResearchMeSH KeywordsAdministration, OralAdrenergic alpha-AgonistsAgedAged, 80 and overBlood PressureDiastoleDizzinessFatigueFemaleFollow-Up StudiesHumansHypotensionKidney Failure, ChronicLongitudinal StudiesMaleMiddle AgedMidodrineMuscle CrampMuscle WeaknessParesthesiaProspective StudiesPulseRenal DialysisRisk FactorsSafetyScalpSystoleConceptsDiastolic blood pressureSystolic blood pressureBlood pressureMidodrine therapyArterial pressureHemodialysis patientsIntradialytic hypotensionPulse rateEnd-stage renal disease patientsIntradialytic systolic blood pressureEfficacy of midodrineSymptomatic hemodialysis patientsNeurogenic orthostatic hypotensionMean arterial pressureRenal disease patientsAdequate patient numbersBlood pressure measurementsAlpha-adrenergic agonist activityConsecutive dialysis sessionsAutonomic dysfunctionDialysis hypotensionOral agentsOrthostatic hypotensionSymptomatic hypotensionProspective trialDysuria in an Elderly Man with Cardiomyopathy
Perazella M, Mahnensmith R. Dysuria in an Elderly Man with Cardiomyopathy. Hospital Practice 1997, 32: 147-154. PMID: 9006590, DOI: 10.1080/21548331.1997.11443412.Peer-Reviewed Original Research
1996
Hyperkalemia in hospitalized patients treated with trimethoprim-sulfamethoxazole.
Alappan R, Perazella M, Buller G. Hyperkalemia in hospitalized patients treated with trimethoprim-sulfamethoxazole. Annals Of Internal Medicine 1996, 124: 316-20. PMID: 8554227, DOI: 10.7326/0003-4819-124-3-199602010-00006.Peer-Reviewed Original ResearchConceptsSerum potassium concentrationSerum creatinine levelsMumol/LBlood urea nitrogen levelsPeak potassium concentrationTrimethoprim-sulfamethoxazole therapyCreatinine levelsUrea nitrogen levelsTrimethoprim-sulfamethoxazoleTreatment groupsPotassium concentrationControl groupCommunity-based teaching hospitalDevelopment of hyperkalemiaDays of therapyProspective chart reviewConcurrent renal insufficiencyRenal insufficiencyChart reviewSevere hyperkalemiaHospitalized patientsSerum sodiumTeaching hospitalAnion gapPatients