2021
Immunotherapy-Related Acute Kidney Injury
Manohar S, Jhaveri KD, Perazella MA. Immunotherapy-Related Acute Kidney Injury. Advances In Kidney Disease And Health 2021, 28: 429-437.e1. PMID: 35190109, DOI: 10.1053/j.ackd.2021.07.006.Peer-Reviewed Original ResearchConceptsChimeric antigen receptor T-cell therapyEffective immune checkpoint inhibitorsAcute kidney injuryImmune checkpoint inhibitorsHigh-dose interleukinNumerous clinical trialsT-cell therapyField of oncologyCheckpoint inhibitorsKidney injuryGeneration immunotherapiesClinical trialsClinical practiceImmunotherapyImmune systemAdverse effectsNephrotoxicityInterleukinPathophysiologyInjuryTherapyCancerOncologyTrials
2020
Onconephrology: The intersections between the kidney and cancer
Rosner MH, Jhaveri KD, McMahon BA, Perazella MA. Onconephrology: The intersections between the kidney and cancer. CA A Cancer Journal For Clinicians 2020, 71: 47-77. PMID: 32853404, DOI: 10.3322/caac.21636.Peer-Reviewed Original ResearchConceptsChronic kidney diseaseDrug-induced nephrotoxicityKidney diseaseElectrolyte disordersAcute kidney injuryStem cell transplantationParaneoplastic glomerulonephritisKidney injuryCell transplantationTherapeutic regimensCollaborative careCancerDiseasePatientsOnconephrologyNew subspecialtySpecific training programsNephrotoxicityDisordersTraining programGlomerulonephritisRegimensNephrologistsTransplantationOncologistsImmune Checkpoint Inhibitors and Immune-Related Adverse Renal Events
Herrmann SM, Perazella MA. Immune Checkpoint Inhibitors and Immune-Related Adverse Renal Events. Kidney International Reports 2020, 5: 1139-1148. PMID: 32775813, PMCID: PMC7403510, DOI: 10.1016/j.ekir.2020.04.018.Peer-Reviewed Original ResearchImmune checkpoint inhibitorsAcute kidney injuryCheckpoint inhibitorsAdverse renal effectsAdverse renal eventsSubset of patientsPotential risk factorsAcute rejectionRenal eventsKidney injuryRenal effectsTransplant populationRenal toxicityRisk factorsBetter outcomesPatientsNephrotoxicityCliniciansCancer therapyCancerRecent studiesInhibitorsCurrent informationComplicationsProviders
2018
35 Kidney Disease Caused by Therapeutic Agents
Perazella M, Shirali A. 35 Kidney Disease Caused by Therapeutic Agents. 2018, 334-344. DOI: 10.1016/b978-0-323-47794-9.00035-4.BooksKidney diseaseTherapeutic agentsDrug-induced renal toxicityProteinuria/nephrotic syndromeFrequent adverse consequencesChronic kidney diseaseChronic kidney injuryDrugs of abuseSubgroup of individualsDrug nephrotoxicityKidney injuryMost medicationsNephrotoxic drugsTubular dysfunctionNephrotic syndromeRenal toxicityDrug therapyRisk factorsTherapeutic medicationsRenal syndromeAppropriate careMedicationsNephrotoxicitySyndromeAdverse consequences
2017
Update on the Renal Effects of Anticancer Agents
Perazella M. Update on the Renal Effects of Anticancer Agents. Journal Of Onco-Nephrology 2017, 1: 170-178. DOI: 10.5301/jo-n.5000026.Peer-Reviewed Original ResearchAnticancer drug nephrotoxicityChronic kidney injuryKidney injuryDrug nephrotoxicityAcute interstitial nephritisAcute kidney injuryAcute tubular injuryNumber of drugsNumber of lesionsAcid-base disturbancesNephrology updateRenal effectsNovel immunotherapiesTubular injuryInterstitial nephritisGlomerular injuryKidney diseaseCancer patientsConventional chemotherapyRenal metabolismSystemic toxicityInjuryNephrotoxicityChemotherapeutic drugsPatients
2001
Selective cyclooxygenase-2 inhibitors: a pattern of nephrotoxicity similar to traditional nonsteroidal anti-inflammatory drugs
Perazella M, Tray K. Selective cyclooxygenase-2 inhibitors: a pattern of nephrotoxicity similar to traditional nonsteroidal anti-inflammatory drugs. The American Journal Of Medicine 2001, 111: 64-67. PMID: 11448662, DOI: 10.1016/s0002-9343(01)00757-4.Peer-Reviewed Original Research
1993
NSAID Nephrotoxicity Revisited: Acute Renal Failure Due to Parenteral Ketorolac
PERAZELLA M, BULLER G. NSAID Nephrotoxicity Revisited: Acute Renal Failure Due to Parenteral Ketorolac. Southern Medical Journal 1993, 86: 1421-1424. PMID: 8272928, DOI: 10.1097/00007611-199312000-00025.Peer-Reviewed Original ResearchConceptsNSAID nephrotoxicityAcute renal failureSevere postoperative painMajor surgical proceduresKetorolac therapyParenteral ketorolacRenal hypoperfusionNonsurgical patientsPostoperative painRenal insufficiencyElderly patientsNonnarcotic analgesicsOral NSAIDsRenal failureRenal functionSuch patientsUrine outputSurgical proceduresKetorolacPatientsMedical literatureNephrotoxicitySuch proceduresSame degreeHypoperfusion