2002
Decreased Synaptic Vesicle Recycling Efficiency and Cognitive Deficits in Amphiphysin 1 Knockout Mice
Di Paolo G, Sankaranarayanan S, Wenk MR, Daniell L, Perucco E, Caldarone BJ, Flavell R, Picciotto MR, Ryan TA, Cremona O, De Camilli P. Decreased Synaptic Vesicle Recycling Efficiency and Cognitive Deficits in Amphiphysin 1 Knockout Mice. Neuron 2002, 33: 789-804. PMID: 11879655, DOI: 10.1016/s0896-6273(02)00601-3.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCerebral CortexClathrinConditioning, ClassicalEndocytosisFluorescent DyesGABA AntagonistsGlutamic AcidHumansMaze LearningMiceMice, KnockoutNerve Tissue ProteinsNeuronsPentylenetetrazoleProtein IsoformsPyridinium CompoundsQuaternary Ammonium CompoundsSurvival RateSynaptic Vesicles
2000
Fear conditioning and latent inhibition in mice lacking the high affinity subclass of nicotinic acetylcholine receptors in the brain
Caldarone B, Duman C, Picciotto M. Fear conditioning and latent inhibition in mice lacking the high affinity subclass of nicotinic acetylcholine receptors in the brain. Neuropharmacology 2000, 39: 2779-2784. PMID: 11044747, DOI: 10.1016/s0028-3908(00)00137-4.Peer-Reviewed Original ResearchConceptsLatent inhibitionFear conditioningLatent inhibition taskTests of cognitionSpecific nicotinic receptor subtypesSpatial learning deficitsCognitive tasksInhibition taskHigh affinity subclassCognitive effectsBehavioral freezingLearning deficitsConditioningFearNicotinic receptor subtypesTaskOverall levelCognitionToneNicotineDeficitsSimilar levelsNicotinic receptorsNicotinic acetylcholine receptorsPrevious studies