Transient transcriptional responses to stress are generated by opposing effects of mRNA production and degradation
Shalem O, Dahan O, Levo M, Martinez M, Furman I, Segal E, Pilpel Y. Transient transcriptional responses to stress are generated by opposing effects of mRNA production and degradation. Molecular Systems Biology 2008, 4: msb200859. PMID: 18854817, PMCID: PMC2583085, DOI: 10.1038/msb.2008.59.Peer-Reviewed Original ResearchConceptsInduced genesRepressed genesMRNA productionTranscriptional responses to stressGenome-wide interplayResponse to stressResponse to environmental changesMRNA decay ratesCondition-specific changesSteady-state levelsTranscriptional arrestGenesTranscriptomeEnvironmental changesMRNARegulatory armYeastMicroarrayDegradationProduction