1998
Hydromorphone–Naloxone Combinations in Opioid-Dependent Humans Under a Naloxone Novel-Response Discrimination Procedure
Oliveto A, Rosen M, Kosten T, Hameedi F, Woods S, Kosten T. Hydromorphone–Naloxone Combinations in Opioid-Dependent Humans Under a Naloxone Novel-Response Discrimination Procedure. Experimental And Clinical Psychopharmacology 1998, 6: 169-178. PMID: 9608349, DOI: 10.1037/1064-1297.6.2.169.Peer-Reviewed Original ResearchConceptsNaloxone-appropriate respondingNovel-appropriate respondingDose-related increaseNovel-response drug discrimination procedureOpioid-dependent humansDose-related decreaseDrug discrimination procedureHuman laboratory modelOpioid withdrawalDiscrimination procedureNaloxoneHydromorphoneNonhuman dataAppropriate respondingRespondingPlaceboMethadone
1997
Treatment of Early AIDS Dementia in Intravenous Drug Users: High Versus Low Dose Peptide T
Kosten T, Rosen M, McMahon T, Bridge T, O'malley S, Pearsall R, O'connor P. Treatment of Early AIDS Dementia in Intravenous Drug Users: High Versus Low Dose Peptide T. The American Journal Of Drug And Alcohol Abuse 1997, 23: 543-553. PMID: 9366972, DOI: 10.3109/00952999709016894.Peer-Reviewed Original Research
1996
A pilot study of dextromethorphan in naloxone-precipitated opiate withdrawal
Rosen M, McMahon T, Woods S, Pearsall H, Kosten T. A pilot study of dextromethorphan in naloxone-precipitated opiate withdrawal. European Journal Of Pharmacology 1996, 307: 251-257. PMID: 8836612, DOI: 10.1016/0014-2999(96)00249-x.Peer-Reviewed Original ResearchConceptsNaloxone-precipitated opiate withdrawalOpiate withdrawalOpiate-dependent subjectsPre-clinical studiesConsiderable inter-individual variabilityPretreatment 1 hInter-individual variabilityIntramuscular naloxoneDextromethorphanPilot studyWithdrawal measuresPlaceboNaloxoneMethadoneWithdrawalSubjectsDifferent daysRandomized design
1993
Carbamazepine vs. Oxazepam for Benzodiazepine Detoxification in Methadone‐Maintained Patients
Rosen M, Pearsall H, Price L, McDougle C, Woods S, Kosten T. Carbamazepine vs. Oxazepam for Benzodiazepine Detoxification in Methadone‐Maintained Patients. American Journal On Addictions 1993, 2: 165-168. DOI: 10.1111/j.1521-0391.1993.tb00217.x.Peer-Reviewed Original Research
1992
Cocaine-Associated Panic Attacks in Methadone-Maintained Patients
Rosen M, Kosten T. Cocaine-Associated Panic Attacks in Methadone-Maintained Patients. The American Journal Of Drug And Alcohol Abuse 1992, 18: 57-62. PMID: 1314016, DOI: 10.3109/00952999209001611.Peer-Reviewed Original ResearchBuprenorphine for cocaine and opiate dependence.
Kosten T, Rosen M, Schottenfeld R, Ziedonis D. Buprenorphine for cocaine and opiate dependence. Psychopharmacology Bulletin 1992, 28: 15-9. PMID: 1609037.Peer-Reviewed Original ResearchConceptsCocaine abuseMixed opioid agonist/antagonistOpioid agonist/antagonistPreliminary human studiesAgonists/antagonistsBuprenorphine treatmentOpioid dependenceMethadone maintenanceClinical trialsConcurrent dependencePreclinical studiesCocaine effectsBuprenorphineHuman studiesPlace preferenceChallenge studiesCocaineMethadoneTreatmentTrialsAbuseDose dependenceOpioidsAntagonistDaily
1991
Buprenorphine: Beyond Methadone?
Rosen M, Kosten T. Buprenorphine: Beyond Methadone? Psychiatric Services 1991, 42: 347-349. PMID: 2050347, DOI: 10.1176/ps.42.4.347.Peer-Reviewed Original ResearchConceptsConnecticut Mental Health CenterHuman immunodeficiency virusPromising new treatmentMental health centersSubstance abuse treatmentDepartment of PsychiatryAbuse of cocaineIntravenous heroinImmunodeficiency virusHealth centersYale University SchoolNew treatmentsAbuse treatmentGuest authorsDrug addictsDr. RosenUniversity SchoolRisk-taking behaviorTreatmentMethadoneResearch UnitHeroinCocaine