2024
Strategies to Deimplement Opioid Prescribing in Primary Care
Quanbeck A, Robinson J, Jacobson N, Li X, Hennessy-Garza R, Landeck J, Cohen A, Madden L, Pulvermacher A, Brown R. Strategies to Deimplement Opioid Prescribing in Primary Care. JAMA Network Open 2024, 7: e2438325. PMID: 39388183, PMCID: PMC11581553, DOI: 10.1001/jamanetworkopen.2024.38325.Peer-Reviewed Original ResearchConceptsCluster randomized clinical trialDeimplementation strategiesMorphine milligram equivalent doseMorphine milligram equivalentsPractice facilitationOpioid prescribingIncreased screeningTreatment agreementsUS health care systemCenters for Disease Control and Prevention guidelinesRandomized clinical trialsUrine drug screensPrimary care clinicsPrimary care settingPrimary outcomeMental health screeningPain-related interferenceHealth care systemHigh-intensity groupEnjoyment of lifeChronic pain managementPrimary careCare clinicsCare settingsHealth screening
2022
A cohort study examining the relationship among housing status, patient characteristics, and retention among individuals enrolled in low-barrier-to-treatment-access methadone maintenance treatment
Gaeta Gazzola M, Carmichael ID, Madden LM, Dasgupta N, Beitel M, Zheng X, Eggert KF, Farnum SO, Barry DT. A cohort study examining the relationship among housing status, patient characteristics, and retention among individuals enrolled in low-barrier-to-treatment-access methadone maintenance treatment. Journal Of Substance Use And Addiction Treatment 2022, 138: 108753. PMID: 35277307, DOI: 10.1016/j.jsat.2022.108753.Peer-Reviewed Original ResearchMeSH KeywordsChronic PainCohort StudiesFemaleHousingHumansMethadoneOpiate Substitution TreatmentRetrospective StudiesConceptsMethadone maintenance treatmentPatient characteristicsChronic painMaintenance treatmentMMT programHousing statusPsychiatric distressCox proportional hazards modelCurrent chronic painPercent of patientsRetrospective chart reviewLog-rank testProportional hazards modelMann-Whitney U testSocial isolationTreatment discontinuationChart reviewCohort studyConsecutive patientsSignificant negative associationHazards modelMeasures of demographicsPatientsSmoking behaviorU test
2021
Primary care and medication management characteristics among patients receiving office-based opioid treatment with buprenorphine
Du CX, Shi J, Tetrault JM, Madden LM, Barry DT. Primary care and medication management characteristics among patients receiving office-based opioid treatment with buprenorphine. Family Practice 2021, 39: 234-240. PMID: 34893825, PMCID: PMC8947790, DOI: 10.1093/fampra/cmab166.Peer-Reviewed Original ResearchConceptsOffice-based opioid treatmentPrimary care providersOpioid use disorderUrine toxicologyOpioid treatmentMore primary care providersOutpatient primary care clinicsChronic pain statusChronic viral hepatitisPrimary care clinicsCommon comorbid conditionsPrimary care characteristicsAddiction treatment settingsHigher median numberEvidence-based treatment modelsOBOT patientsOBOT programOlder patientsPain statusViral hepatitisCommon medicationsRetrospective reviewCare clinicsChronic painComorbid conditionsA Pilot Investigation of Nonpharmacological Pain Management Intervention Groups in Methadone Maintenance Treatment
DiMeola KA, Haynes J, Barone M, Beitel M, Madden LM, Cutter CJ, Raso A, Gaeta M, Zheng X, Barry DT. A Pilot Investigation of Nonpharmacological Pain Management Intervention Groups in Methadone Maintenance Treatment. Journal Of Addiction Medicine 2021, 16: 229-234. PMID: 34145187, PMCID: PMC8678387, DOI: 10.1097/adm.0000000000000877.Peer-Reviewed Original ResearchMeSH KeywordsAdultChronic PainFemaleHumansMaleMethadoneOpiate Substitution TreatmentPain ManagementPilot ProjectsConceptsMethadone maintenance treatmentCurrent pain intensityPain intensityMaintenance treatmentAcute increaseIntervention groupCurrent chronic painMood statesCognitive behavioral therapyMMT clinicsChronic painAcute improvementAcute reductionAcute changesSpecific mood statesPainExergame interventionGroup attendanceUnvalidated measuresMonday-FridayPilot investigationBonferroni correctionPatientsT-testInterventionPsychiatric comorbidity and order of condition onset among patients seeking treatment for chronic pain and opioid use disorder
Barry DT, Beitel M, Cutter CJ, Fiellin DA, Madden LM, Lipkind N, Bollampally P, Liong C, Schottenfeld RS. Psychiatric comorbidity and order of condition onset among patients seeking treatment for chronic pain and opioid use disorder. Drug And Alcohol Dependence 2021, 221: 108608. PMID: 33667784, PMCID: PMC8026725, DOI: 10.1016/j.drugalcdep.2021.108608.Peer-Reviewed Original ResearchConceptsOpioid use disorderChronic painPsychiatric comorbidityCondition onsetUse disordersNonopioid substance use disordersDSM-IV-TR Axis I DisordersFirst groupComorbid chronic painStructured Clinical InterviewAxis I DisordersAxis II disordersSubstance use disordersDSM-IV personality disordersStandardized training protocolSame time groupsPotential treatment implicationsClinical trialsDoctoral-level providersI disordersMultinomial logistic regressionPrimary drugClinical InterviewPainDiagnostic Interview
2018
An evaluation of the feasibility, acceptability, and preliminary efficacy of cognitive-behavioral therapy for opioid use disorder and chronic pain
Barry DT, Beitel M, Cutter CJ, Fiellin DA, Kerns RD, Moore BA, Oberleitner L, Madden LM, Liong C, Ginn J, Schottenfeld RS. An evaluation of the feasibility, acceptability, and preliminary efficacy of cognitive-behavioral therapy for opioid use disorder and chronic pain. Drug And Alcohol Dependence 2018, 194: 460-467. PMID: 30508769, PMCID: PMC6312460, DOI: 10.1016/j.drugalcdep.2018.10.015.Peer-Reviewed Original ResearchConceptsOpioid use disorderCognitive behavioral therapyChronic painPreliminary efficacyDrug counselingUse disordersImproved pain outcomesProportion of patientsMethadone-maintained patientsNonmedical opioid useEnd of treatmentPrimary study aimPatient satisfaction ratingsManualized cognitive behavioral therapyOpioid usePain outcomesPain interferenceClinical trialsStandard drug counselingPatientsMean sessionSecondary aimStudy aimPainPilot studyTraining Addiction Counselors to Deliver a Brief Psychoeducational Intervention for Chronic Pain among Patients in Opioid Agonist Treatment: A Pilot Investigation
Butner JL, Bone C, Martinez C, Kwon G, Beitel M, Madden LM, Bono MH, Eller A, Barry DT. Training Addiction Counselors to Deliver a Brief Psychoeducational Intervention for Chronic Pain among Patients in Opioid Agonist Treatment: A Pilot Investigation. Substance Use & Addiction Journal 2018, 39: 199-205. PMID: 29522379, DOI: 10.1080/08897077.2018.1449052.Peer-Reviewed Original ResearchConceptsPsychosocial interventionsBrief psychosocial interventionAddiction counselorsBrief psychoeducational interventionChronic painRole of counselorsAbsence of trainingPerceived AbilityAppropriate treatment interventionsCounselor's abilityPsychoeducational interventionTreatment counselorsDrug counselorsPositive attitudesTreatment interventionsCounselorsFuture researchKnowledge scorePilot investigationTrainingPre-test knowledge scoreOpioid agonist treatmentAppropriate interventionsInterventionAttitudesA randomized matched-pairs study of feasibility, acceptability, and effectiveness of systems consultation: a novel implementation strategy for adopting clinical guidelines for Opioid prescribing in primary care
Quanbeck A, Brown RT, Zgierska AE, Jacobson N, Robinson JM, Johnson RA, Deyo BM, Madden L, Tuan WJ, Alagoz E. A randomized matched-pairs study of feasibility, acceptability, and effectiveness of systems consultation: a novel implementation strategy for adopting clinical guidelines for Opioid prescribing in primary care. Implementation Science 2018, 13: 21. PMID: 29370813, PMCID: PMC5784593, DOI: 10.1186/s13012-018-0713-1.Peer-Reviewed Original ResearchMeSH KeywordsAnalgesics, OpioidChronic PainDelivery of Health CareEvidence-Based PracticeFemaleFocus GroupsGuideline AdherenceHumansInterviews as TopicMaleOpioid-Related DisordersPractice Guidelines as TopicPractice Patterns, Physicians'Primary Health CareQualitative ResearchReferral and ConsultationResearch DesignConceptsOpioid prescribingIntervention clinicsClinical guidelinesPrimary careMorphine equivalent daily doseSafe opioid prescribingPercentage of patientsPrimary care clinicsMental health screenUrine drug testsRE-AIM frameworkDiscrete implementation strategiesMatched-pair studyInnovative implementation strategyDaily doseCare clinicsChronic painAcademic detailingTreatment agreementsHealth screenChronic conditionsImplementation strategiesOpioid abuseControl clinicsMixed-method evaluation
2017
Drug Counselor Responses to Patients’ Pain Reports: A Qualitative Investigation of Barriers and Facilitators to Treating Patients with Chronic Pain in Methadone Maintenance Treatment
Beitel M, Oberleitner L, Kahn M, Kerns RD, Liong C, Madden LM, Ginn J, Barry DT. Drug Counselor Responses to Patients’ Pain Reports: A Qualitative Investigation of Barriers and Facilitators to Treating Patients with Chronic Pain in Methadone Maintenance Treatment. Pain Medicine 2017, 18: 2152-2161. PMID: 28177509, DOI: 10.1093/pm/pnw327.Peer-Reviewed Original ResearchConceptsOpioid use disorderMethadone maintenance treatmentChronic painDrug counselorsMaintenance treatmentTreatment needsUse disordersMedical providersCo-occurring chronic painMethadone maintenance treatment programPain management referralsChronic noncancer painPatient-related barriersMethadone-maintained patientsTreatment of patientsMaintenance treatment programPatients' treatment needsNoncancer painMedication regimensPain managementManagement referralsTreatment adherencePatient improvementPatient reportsPain
2016
Physical activity, psychiatric distress, and interest in exercise group participation among individuals seeking methadone maintenance treatment with and without chronic pain
Beitel M, Stults-Kolehmainen M, Cutter CJ, Schottenfeld RS, Eggert K, Madden LM, Kerns RD, Liong C, Ginn J, Barry DT. Physical activity, psychiatric distress, and interest in exercise group participation among individuals seeking methadone maintenance treatment with and without chronic pain. American Journal On Addictions 2016, 25: 125-131. PMID: 26824197, DOI: 10.1111/ajad.12336.Peer-Reviewed Original ResearchConceptsMethadone maintenance treatmentPhysical activity levelsExercise group participationChronic painPhysical activityPsychiatric distressMaintenance treatmentActivity levelsPast weekVigorous-intensity physical activityExercise of patientsIntensity physical activityExercise groupExercise interventionPainBrief self-report instrumentPatientsLow levelsSelf-report instrumentDistressWeeksDepressionTreatmentGroup participationParticipants