2017
Novel Pharmacologic Candidates for Treatment of Primary Open-Angle Glaucoma.
Lu LJ, Tsai JC, Liu J. Novel Pharmacologic Candidates for Treatment of Primary Open-Angle Glaucoma. The Yale Journal Of Biology And Medicine 2017, 90: 111-118. PMID: 28356898, PMCID: PMC5369028.Peer-Reviewed Original ResearchConceptsPrimary open-angle glaucomaOpen-angle glaucomaIntraocular pressureProstaglandin analoguesDrug-related side effectsCurrent medical treatment optionsLowering of IOPTarget intraocular pressureMedical treatment optionsVisual field lossAlpha-adrenergic agonistsNew pharmacologic optionsLower intraocular pressureMultiple daily administrationBeta-adrenergic antagonistsAdenosine receptor agonistsLow patient complianceAqueous humor outflowRho-kinase inhibitorTrabecular meshwork outflow pathwaysLatanoprostene bunodPharmacologic optionsPharmacologic treatmentTopical medicationsDaily administration
2015
Marijuana for Glaucoma: A Recipe for Disaster or Treatment?
Sun X, Xu CS, Chadha N, Chen A, Liu J. Marijuana for Glaucoma: A Recipe for Disaster or Treatment? The Yale Journal Of Biology And Medicine 2015, 88: 265-9. PMID: 26339209, PMCID: PMC4553646.Peer-Reviewed Original ResearchConceptsCannabis use disorderIntraocular pressureGlaucoma patientsGlaucoma treatmentAdverse effectsMost glaucoma patientsLower intraocular pressurePsychological adverse effectsTreatment of glaucomaNumerous adverse effectsSignificant adverse effectsWithdrawal symptomsPossible progressionUse disordersUse of marijuanaSubstance abuseMedical marijuanaRare circumstancesFurther studiesTreatmentPatientsGlaucomaCannabinoid moleculesMarijuanaDeleterious effects