Systematic review and meta-analysis of outcomes in patients with suspected pulmonary embolism
Patel P, Patel P, Bhatt M, Braun C, Begum H, Nieuwlaat R, Khatib R, Martins C, Zhang Y, Etxeandia-Ikobaltzeta I, Varghese J, Alturkmani H, Bahaj W, Baig M, Kehar R, Mustafa A, Ponnapureddy R, Sethi A, Thomas M, Wooldridge D, Lim W, Bates S, Lang E, Le Gal G, Haramati L, Kline J, Righini M, Wiercioch W, Schünemann H, Mustafa R. Systematic review and meta-analysis of outcomes in patients with suspected pulmonary embolism. Blood Advances 2021, 5: 2237-2244. PMID: 33900385, PMCID: PMC8095140, DOI: 10.1182/bloodadvances.2020002398.Peer-Reviewed Original ResearchConceptsIncidence of VTENegative D-dimerPulmonary embolismVenous thromboembolismPretest probabilityMajor bleedingD-dimerNegative computed tomography scanRecurrent venous thromboembolismCochrane Central RegisterRecurrent pulmonary embolismLow pretest probabilityIntermediate pretest probabilityRelevant conference proceedingsComputed tomography scanHigh pretest probabilityPostthrombotic sequelaeCause mortalityCentral RegisterControlled TrialsIntracranial hemorrhagePrompt evaluationDiagnostic pathwayEligible studiesTomography scan