2004
Location of the epitope for an anti-CD8α antibody 53.6.7 which enhances CD8α-MHC class I interaction indicates antibody stabilization of a higher affinity CD8 conformation
Devine L, Hodsdon ME, Daniels MA, Jameson SC, Kavathas PB. Location of the epitope for an anti-CD8α antibody 53.6.7 which enhances CD8α-MHC class I interaction indicates antibody stabilization of a higher affinity CD8 conformation. Immunology Letters 2004, 93: 123-130. PMID: 15158607, DOI: 10.1016/j.imlet.2004.02.002.Peer-Reviewed Original ResearchAnimalsAntibodies, MonoclonalAntibody AffinityAntibody SpecificityBiotinylationCD8 AntigensChlorocebus aethiopsCOS CellsEgg ProteinsEpitope MappingEscherichia coliFlow CytometryH-2 AntigensHistocompatibility Antigens Class IMiceModels, MolecularMutagenesis, Site-DirectedOligopeptidesOvalbuminPeptide FragmentsProtein BindingProtein ConformationTransfection
2001
CD8 Binding to MHC Class I Molecules Is Influenced by T Cell Maturation and Glycosylation
Daniels M, Devine L, Miller J, Moser J, Lukacher A, Altman J, Kavathas P, Hogquist K, Jameson S. CD8 Binding to MHC Class I Molecules Is Influenced by T Cell Maturation and Glycosylation. Immunity 2001, 15: 1051-1061. PMID: 11754824, DOI: 10.1016/s1074-7613(01)00252-7.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsATP Binding Cassette Transporter, Subfamily B, Member 2ATP-Binding Cassette TransportersCD3 ComplexCD4-Positive T-LymphocytesCD8 AntigensCD8-Positive T-LymphocytesCell AdhesionCell DifferentiationCellular SenescenceGlycosylationH-2 AntigensHistocompatibility Antigen H-2DLigandsMacromolecular SubstancesMembrane GlycoproteinsMiceMice, Inbred BALB CMice, Inbred C57BLMice, KnockoutN-Acetylneuraminic AcidNeuraminidaseOvalbuminPeptide FragmentsProtein BindingProtein Processing, Post-TranslationalReceptors, Antigen, T-Cell, alpha-betaRheologySolubilityThymus GlandT-Lymphocyte SubsetsConceptsGlycosylation stateT cell maturationCell maturationT cell adhesionDevelopmental regulationDouble-positive thymocytesCell adhesionT cell activationClass I MHC tetramersAdhesion moleculesCell activationMHC class I moleculesMaturationClass I moleculesClass I MHC moleculesI MHC moleculesI moleculesMoleculesGlycosylationMHC ligandsRegulationMHC moleculesClass I MHCBindingSialylation
1996
Lymphocyte Migration across the Anterior and Posterior Blood–Retinal Barrierin Vitro
Devine L, Lightman S, Greenwood J. Lymphocyte Migration across the Anterior and Posterior Blood–Retinal Barrierin Vitro. Cellular Immunology 1996, 168: 267-275. PMID: 8640874, DOI: 10.1006/cimm.1996.0075.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntigensArrestinBlood-Retinal BarrierCell AdhesionCell LineChemotaxis, LeukocyteEndothelium, VascularEye ProteinsInterferon-gammaInterleukin-1Lymph NodesLymphocyte ActivationLymphocyte SubsetsMuromonab-CD3OvalbuminPigment Epithelium of EyeRatsRats, Inbred LewRats, Inbred StrainsReceptor-CD3 Complex, Antigen, T-CellRecombinant ProteinsRetinal VesselsSpecific Pathogen-Free OrganismsT-Lymphocytes, Helper-InducerTuberculinConceptsAntigen-specific T cell linesRat retinal pigment epitheliumBlood-retinal barrierT cell linesPLN cellsEndothelial cellsLymphocyte migrationPeripheral lymph node cellsCell linesRetinal vascular endotheliumLymph node cellsCross-linking CD3Migration of lymphocytesRetinal endothelial cellsRetinal pigment epitheliumCombination of CD3PVG ratsRetinal endotheliumIFN-gamma activationLewis ratsNode cellsS-antigenICAM-1IFN-gammaPigment epithelium