2015
How Neurons Communicate: Gap Junctions and Neurosecretion
Levitan I, Kaczmarek L. How Neurons Communicate: Gap Junctions and Neurosecretion. 2015, 153-186. DOI: 10.1093/med/9780199773893.003.0008.ChaptersSynaptic vesiclesSNARE complex proteinsExistence of proteinsSecretion of neurotransmittersComplex proteinsPlasma membraneCytoplasmic vesiclesProteinVesiclesAdjacent cellsGap junctionsSmall moleculesCalcium entryExternal mediumElectrical couplingMembraneNeurosecretionCellsComplex processEndocytosisExocytosisFluorescent dyeMoleculesConnexinsCytoplasmSynaptic Release of Neurotransmitters
Levitan I, Kaczmarek L. Synaptic Release of Neurotransmitters. 2015, 187-212. DOI: 10.1093/med/9780199773893.003.0009.ChaptersSynaptic vesiclesIndividual synaptic vesiclesRapid synaptic transmissionGenetic experimentsVoltage-dependent channelsEntry of calciumAmount of transmitterRelease of neurotransmittersSquid stellate ganglionFrog neuromuscular junctionNeurotransmitter releasePhysiological experimentsStellate ganglionSpecific synapsesSpecialized synapsesSynaptic transmissionSynaptic releaseRepetitive stimulationVesiclesPresynaptic terminalsNeuromuscular junctionAction potentialsFurther insightNeurotransmittersExocytosisForm and Function in Cells of the Brain
Levitan I, Kaczmarek L. Form and Function in Cells of the Brain. 2015, 23-38. DOI: 10.1093/med/9780199773893.003.0002.Chapters
1998
Activation of Kv3.1 channels in neuronal spine-like structures may induce local potassium ion depletion
Wang L, Gan L, Perney T, Schwartz I, Kaczmarek L. Activation of Kv3.1 channels in neuronal spine-like structures may induce local potassium ion depletion. Proceedings Of The National Academy Of Sciences Of The United States Of America 1998, 95: 1882-1887. PMID: 9465111, PMCID: PMC19207, DOI: 10.1073/pnas.95.4.1882.Peer-Reviewed Original ResearchConceptsSpine-like structuresIon channelsMembrane structureMembrane compartmentsVesicle compartmentKv3.1 channelsBulk cytoplasmElectron immunomicroscopyCHO cellsPostsynaptic membraneVesiclesMembrane patchesSpine-like protrusionsNeuronal membrane structurePotassium channel Kv3.1Channel Kv3.1CellsComplete inactivationInactivationCompartmentsRapid depletionCentral nervous systemSlow refillingSynaptic stimulationNeuronal structures
1996
Developmental dissociation of excitability and secretory ability in Aplysia bag cell neurons
Nick T, Moreira J, Kaczmarek L, Carew T, Wayne N. Developmental dissociation of excitability and secretory ability in Aplysia bag cell neurons. Journal Of Neurophysiology 1996, 76: 3351-3359. PMID: 8930278, DOI: 10.1152/jn.1996.76.5.3351.Peer-Reviewed Original ResearchConceptsBag cell neuronsEgg-laying behaviorCell neuronsPotential functional significanceAplysia bag cell neuronsDevelopmental regulationVesicular localizationSecretory vesiclesJuvenile AplysiaPremature expressionImmature neuronsDownstream elementsMature formBody sizeReproductive behaviorImmunoelectron microscopyPotassium channel blocker tetraethylammoniumLarge vesiclesDevelopmental interactionsFunctional significanceBag cell hormonesVesiclesCessation of locomotionMature neuronsElectrical activity