2024
Rare de novo damaging DNA variants are enriched in attention-deficit/hyperactivity disorder and implicate risk genes
Olfson E, Farhat L, Liu W, Vitulano L, Zai G, Lima M, Parent J, Polanczyk G, Cappi C, Kennedy J, Fernandez T. Rare de novo damaging DNA variants are enriched in attention-deficit/hyperactivity disorder and implicate risk genes. Nature Communications 2024, 15: 5870. PMID: 38997333, PMCID: PMC11245598, DOI: 10.1038/s41467-024-50247-7.Peer-Reviewed Original ResearchConceptsDNA sequencesRisk genesHigh-confidence risk genesWhole-exome DNA sequencingSequencing of familiesIdentified de novoLysine demethylase 5BDNA variantsTrio cohortBiological pathwaysGenesSequencing cohortGenetic factorsChildhood neurodevelopmental disordersAttention-deficit/hyperactivity disorderSequenceVariantsADHD riskNeurodevelopmental disordersKDM5BDNAMutationsFamilyLysineDiscovery
2003
Biopsychosocial issues and risk factors in the family when the child has a chronic illness
Lewis M, Vitulano LA. Biopsychosocial issues and risk factors in the family when the child has a chronic illness. Child And Adolescent Psychiatric Clinics Of North America 2003, 12: 389-399. PMID: 12910814, DOI: 10.1016/s1056-4993(03)00024-5.Peer-Reviewed Original ResearchConceptsChronic health conditionsChronic illnessHealth conditionsRisk factorsHealthy peersPsychiatric problemsBiopsychosocial issuesSocioeconomic statusBehavioral medicineChildrenIllnessSocial supportClinical demandFamily functioningAmerican childrenAdolescentsPsychological aspectsDiagnosisImpairment