2020
RPE Polarity and Barrier Function
Rizzolo L. RPE Polarity and Barrier Function. 2020, 19-45. DOI: 10.1007/978-3-030-28384-1_2.ChaptersCell polarityEpithelial cell polarityPlasma membrane domainsTight junctionsBasolateral plasma membraneRPE polarityCellular processesMembrane domainsPlasma membraneMembrane transportersMembrane transportNeighboring cellsRPE phenotypeSemi-selective barrierProteinBarrier functionJunction proteinsRPE functionParacellular spaceOuter blood-retinal barrierVisual cycleTight junction proteinsTransepithelial electrical resistanceAsymmetric distributionDynamic interplay
1998
Protein-Binding Domains of the Tight Junction Protein, ZO-2, Are Highly Conserved between Avian and Mammalian Species
Collins J, Rizzolo L. Protein-Binding Domains of the Tight Junction Protein, ZO-2, Are Highly Conserved between Avian and Mammalian Species. Biochemical And Biophysical Research Communications 1998, 252: 617-622. PMID: 9837755, DOI: 10.1006/bbrc.1998.9710.Peer-Reviewed Original ResearchConceptsProtein-binding domainsSrc homology 3ZO-2ZO-3Homologous domainsMAGUK protein familyDistinct PDZ domainsProtein binding domainsZO-1Apical junctional complexHomology 3PDZ domainProtein familySH3 domainAcidic domainEvolutionary pressureMammalian speciesJunctional complexesEmbryonic chicken retinaJunction proteinsTight junctionsDifferent functionsProteinTight junction proteinsSequence
1997
Remodeling of junctional complexes during the development of the outer blood‐retinal barrier
Williams C, Rizzolo L. Remodeling of junctional complexes during the development of the outer blood‐retinal barrier. The Anatomical Record 1997, 249: 380-388. PMID: 9372172, DOI: 10.1002/(sici)1097-0185(199711)249:3<380::aid-ar9>3.0.co;2-y.Peer-Reviewed Original ResearchConceptsRetinal pigment epitheliumApical junctional complexOuter blood-retinal barrierBlood-retinal barrierNeural retinaZO-1Junctional complexesOccludin expressionRPE developmentMature retinal pigment epitheliumRPE/choroidZO-1 expressionTight junction proteinsEmbryonic day 3Same molecular massEmbryonic day 10Adherens junctionsPigment epitheliumDay 3Day 10Homologous complexesMolecular massRetinaJunction proteinsJunction permeability