Apical Orientation of the Microtubule Organizing Center and Associated γ-Tubulin during the Polarization of the Retinal Pigment Epithelium in Vivo
Rizzolo L, Joshi H. Apical Orientation of the Microtubule Organizing Center and Associated γ-Tubulin during the Polarization of the Retinal Pigment Epithelium in Vivo. Developmental Biology 1993, 157: 147-156. PMID: 8482407, DOI: 10.1006/dbio.1993.1119.Peer-Reviewed Original ResearchConceptsMicrotubule arraysCell polarityEmbryonic day 3Apical membraneGamma-tubulin fociJunctional complexesSimple epithelial cellsMicrotubule organizing centerDevelopment of epitheliaCentrosomal proteinsJuxtanuclear regionΓ-tubulinUnique reorganizationBasal axisGamma-tubulinCell-basement membrane interactionsFunctional polarityMicrotubule growthMembrane interactionsOrganizing centerPrimary cell culturesCultured cellsEpithelial cellsRetinal pigment epitheliumCell cultures