Novel antigen expression of HLA-DR53 in patients with DR7 and DQ9 haplotype
Rivera J, Rewinski M, Bow L, DeVivo J, Michalski T, Alberghini T, Doyle P. Novel antigen expression of HLA-DR53 in patients with DR7 and DQ9 haplotype. Human Immunology 2015, 76: 122. DOI: 10.1016/j.humimm.2015.07.171.Peer-Reviewed Original ResearchPositive B cell crossmatchB-cell crossmatchDR/DQAllocation of organsPossibility of antibodySerology typingHLA-DR53HLA phenotypesReflex testingCaucasian patientsLeukemia patientsReal-time PCRAntigen expressionOrgan donorsPatientsDR53 antigenDR53AntibodiesAdditional typingGenotype associationsAntigenTypingCommon null alleleRecipientsUnexpected expressionConundrum: A negative crossmatch in a patient with high level donor specific antibody
Rewinski M, Alberghini T, Bow L, Devivo J, Doyle P, Michalski P, Ortiz-Rivera J. Conundrum: A negative crossmatch in a patient with high level donor specific antibody. Human Immunology 2015, 76: 57. DOI: 10.1016/j.humimm.2015.07.082.Peer-Reviewed Original ResearchDonor-specific antibodiesB-cell crossmatchDonor-recipient pairsNegative crossmatchMedian fluorescence intensityVirtual crossmatchPresence of DSAPositive B cell crossmatchSpecific antibodiesIncompatible donor-recipient pairsFlow crossmatchAntibody levelsPositive donorsSAB assayAntibody testingHigh-resolution typingClinical significanceT cellsHLA typingPatient seraCrossmatchEP serumClass IIDQ7RT-PCR