2013
β-Blockers associated with no class-specific survival benefit in acute intracerebral hemorrhage
Shoup JP, Winkler J, Czap A, Staff I, Fortunato G, McCullough LD, Sansing LH. β-Blockers associated with no class-specific survival benefit in acute intracerebral hemorrhage. Journal Of The Neurological Sciences 2013, 336: 127-131. PMID: 24183854, PMCID: PMC4956481, DOI: 10.1016/j.jns.2013.10.022.Peer-Reviewed Original ResearchConceptsΒ-blocker treatmentΒ-blocker useBlood pressure controlAcute intracerebral hemorrhageIntracerebral hemorrhageAdrenergic antagonistsAntihypertensive therapyPressure controlInflammation-induced injuryΒ-blocker therapyDatabase of patientsSympathetic nervous systemSpontaneous intracerebral hemorrhageAntihypertensive treatmentInpatient deathSurvival benefitImproved survivalOngoing trialsMultivariable analysisICH patientsImmune activationInpatient stayRetrospective analysisStudy populationΒ-blockers
2009
Who will participate in acute stroke trials?
Kasner SE, Del Giudice A, Rosenberg S, Sheen M, Luciano JM, Cucchiara BL, Messé S, Sansing LH, Baren JM. Who will participate in acute stroke trials? Neurology 2009, 72: 1682-1688. PMID: 19433742, PMCID: PMC2683644, DOI: 10.1212/wnl.0b013e3181a55fbe.Peer-Reviewed Original ResearchMeSH KeywordsAcute DiseaseAgedAttitude to HealthBiomedical ResearchCaregiversClinical Trials as TopicCultureData CollectionFemaleHumansInformed ConsentMaleMental CompetencyMiddle AgedPatient CompliancePatient Education as TopicPhysician-Patient RelationsProspective StudiesRisk AssessmentRisk-TakingStrokeConceptsAcute treatment trialsAcute strokeTreatment trialsClinical trialsAcute stroke treatment trialsAcute stroke clinical trialsMean age 63Stroke treatment trialsVascular risk factorsMinority of patientsAcute stroke trialsStroke clinical trialsNovel therapeutic agentsStroke severityClinical factorsPrimary outcomeStroke trialsAcute trialProspective surveyTrial interventionRisk factorsStroke typeHigh incidenceAge 63Patients