Featured Publications
Mineralocorticoid and Estrogen Receptors in Endothelial Cells Coordinately Regulate Microvascular Function in Obese Female Mice
Biwer L, Carvajal B, Lu Q, Man J, Jaffe I. Mineralocorticoid and Estrogen Receptors in Endothelial Cells Coordinately Regulate Microvascular Function in Obese Female Mice. Hypertension 2021, 77: 2117-2126. PMID: 33934622, PMCID: PMC8119365, DOI: 10.1161/hypertensionaha.120.16911.Peer-Reviewed Original Research
2020
Myoendothelial Junctions of Mature Coronary Vessels Express Notch Signaling Proteins
McCallinhart P, Biwer L, Clark O, Isakson B, Lilly B, Trask A. Myoendothelial Junctions of Mature Coronary Vessels Express Notch Signaling Proteins. Frontiers In Physiology 2020, 11: 29. PMID: 32116749, PMCID: PMC7010921, DOI: 10.3389/fphys.2020.00029.Peer-Reviewed Original ResearchInternal elastic laminaMyoendothelial junctionsCoronary circulationCoronary ECsBlood vesselsIntact blood vesselsNotch signalingSmooth muscleMature blood vesselsNotch3 expressionNotch inhibitorsNotch receptorsElastic laminaTranswell insertsCell phenotypeNormal vasculogenesisVSMCsCell contactReceptorsCritical determinantCell-cell contactSignalingVesselsNotch activityCritical sites