2016
Vascular effects of alpha hemoglobin stabilizing protein deletion
Biwer L, Lechauve C, Billaud M, Weiss M, Isakson B. Vascular effects of alpha hemoglobin stabilizing protein deletion. The FASEB Journal 2016, 30 DOI: 10.1096/fasebj.30.1_supplement.1276.3.Peer-Reviewed Original ResearchSmooth muscle cellsEndothelial cellsMyoendothelial junctionsNeighboring smooth muscle cellsMean arterial pressureBlood pressure measurementsAlpha hemoglobinConcentration-dependent mannerAvailable nitric oxideArterial pressureVascular effectsResistance arteriesKnockout miceENOS interactionMuscle cellsNitric oxideHemoglobin HENOSMiceNational InstitutePercent distributionHemoglobinPressure measurementsHemoglobin betaPLA signals
2015
Endothelial nitric oxide synthase in the microcirculation
Shu X, Keller T, Begandt D, Butcher J, Biwer L, Keller A, Columbus L, Isakson B. Endothelial nitric oxide synthase in the microcirculation. Cellular And Molecular Life Sciences 2015, 72: 4561-4575. PMID: 26390975, PMCID: PMC4628887, DOI: 10.1007/s00018-015-2021-0.Peer-Reviewed Original ResearchConceptsEndothelial nitric oxide synthaseNitric oxide synthaseOxide synthaseAnti-inflammatory mediatorsRegulation of eNOSRed blood cellsMicrovascular effectsVessel toneImmune responsePharmacological agentsENOS enzymeNitric oxideBlood cellsNO actionKey moleculesENOSVariety of effectsPhysiological roleCellsVasodilatorsSynthaseMicrocirculation