2024
Artificial intelligence applied to electrocardiographic images for the risk stratification of cancer therapeutics-related cardiac dysfunction
Oikonomou E, Sangha V, Dhingra L, Aminorroaya A, Coppi A, Krumholz H, Baldassarre L, Khera R. Artificial intelligence applied to electrocardiographic images for the risk stratification of cancer therapeutics-related cardiac dysfunction. European Heart Journal 2024, 45: ehae666.3190. DOI: 10.1093/eurheartj/ehae666.3190.Peer-Reviewed Original ResearchCancer therapeutics-related cardiac dysfunctionImmune checkpoint inhibitorsGlobal longitudinal strainLeft ventricular systolic dysfunctionNon-Hodgkin's lymphomaCardiac dysfunctionAI-ECGNegative control analysesAssociated with higher incidenceVentricular systolic dysfunctionCohort of patientsRisk stratification strategiesCheckpoint inhibitorsTrastuzumab exposureSystolic dysfunctionRisk stratificationBreast cancerRisk biomarkersSecondary outcomesLongitudinal strainStratification strategiesTrastuzumabPatientsHigher incidenceAnthracyclines
2022
Novel Cardiac Computed Tomography Methods for the Assessment of Anthracycline Induced Cardiotoxicity
Feher A, Baldassarre LA, Sinusas AJ. Novel Cardiac Computed Tomography Methods for the Assessment of Anthracycline Induced Cardiotoxicity. Frontiers In Cardiovascular Medicine 2022, 9: 875150. PMID: 35571206, PMCID: PMC9094702, DOI: 10.3389/fcvm.2022.875150.Peer-Reviewed Original ResearchCardiac structureEpicardial coronary arteriesAnthracycline-induced cardiotoxicityAnti-cancer therapyCoronary vasoreactivityCoronary anatomyCoronary arteryInduced cardiotoxicityCardiac functionCardiotoxic effectsPreprocedural planningExtracellular volumeMyocardial deformationPotential roleCardiotoxicityMolecular imagingCurrent manuscriptVasoreactivityComputed tomography methodArteryAnthracyclinesTherapyCardiacPlaquesEvaluation