Competition between the Rex1 exonuclease and the La protein affects both Trf4p-mediated RNA quality control and pre-tRNA maturation
Copela LA, Fernandez CF, Sherrer RL, Wolin SL. Competition between the Rex1 exonuclease and the La protein affects both Trf4p-mediated RNA quality control and pre-tRNA maturation. RNA 2008, 14: 1214-1227. PMID: 18456844, PMCID: PMC2390804, DOI: 10.1261/rna.1050408.Peer-Reviewed Original ResearchConceptsLa proteinQuality control pathwaysPre-tRNA maturationRNA quality controlWild-type cellsChoice of pathwaySRP RNAExonucleolytic trimmingAberrant RNAsDefective RNAsMutant yeastFunctional RNAsMajor exonucleaseNoncoding RNAsControl pathwaysRNAExonucleaseTrf4pProteinYeastPathwayCellsNascentAccumulationMaturation