2006
Development and validation of nomograms for predicting residual tumor size and the probability of successful conservative surgery with neoadjuvant chemotherapy for breast cancer
Rouzier R, Pusztai L, Garbay J, Delaloge S, Hunt KK, Hortobagyi GN, Berry D, Kuerer HM. Development and validation of nomograms for predicting residual tumor size and the probability of successful conservative surgery with neoadjuvant chemotherapy for breast cancer. Cancer 2006, 107: 1459-1466. PMID: 16948128, DOI: 10.1002/cncr.22177.Peer-Reviewed Original ResearchConceptsResidual tumor sizeBreast conservation therapyNeoadjuvant chemotherapyBreast conservation surgeryBreast cancer patientsTumor sizeConservation therapyBreast conservationConservation surgeryCancer patientsAnthracycline-based neoadjuvant chemotherapyD. Anderson Cancer CenterPaclitaxel neoadjuvant chemotherapyPreoperative chemotherapy regimenPreoperative chemotherapy regimensSuccessful conservative surgeryValidation of nomogramsInstitut Gustave RoussyAnderson Cancer CenterLogistic regression modelsChemotherapy regimenChemotherapy regimensConservative surgeryClinicopathologic dataCancer Center
2001
Surgical conservation planning after neoadjuvant chemotherapy for stage II and operable stage III breast carcinoma
Kuerer H, Singletary S, Buzdar A, Ames F, Valero V, Buchholz T, Ross M, Pusztai L, Hortobagyi G, Hunt K. Surgical conservation planning after neoadjuvant chemotherapy for stage II and operable stage III breast carcinoma. The American Journal Of Surgery 2001, 182: 601-608. PMID: 11839324, DOI: 10.1016/s0002-9610(01)00793-0.Peer-Reviewed Original ResearchConceptsLocal-regional recurrence rateOperable breast cancerPrimary tumorBreast cancerTumor downstagingNeoadjuvant chemotherapyResidual carcinomaRecurrence rateStage III breast carcinomaStage IIComplete clinical responseCycles of chemotherapyMedian tumor sizeAxillary node dissectionBreast conservation surgeryNode dissectionClinical responseProspective trialSurgical resectionPalpable massSegmental resectionAdequate resectionPathologic examinationTumor sizeLarge tumors