2024
The Great Controversy of Obstructive Sleep Apnea Treatment for Cardiovascular Risk Benefit: Advancing the Science Through Expert Consensus. An Official American Thoracic Society Workshop Report.
Cohen O, Kundel V, Barbé F, Peker Y, McEvoy D, Sánchez-de-la-Torre M, Gottlieb D, Bradley T, Suárez-Fariñas M, Zinchuk A, Azarbarzin A, Malhotra A, Schotland H, Gozal D, Jelic S, Ramos A, Martin J, Pamidi S, Johnson D, Mehra R, Somers V, Hoyos C, Jackson C, Alcantara C, Billings M, Bhatt D, Patel S, Redline S, Yaggi H, Shah N. The Great Controversy of Obstructive Sleep Apnea Treatment for Cardiovascular Risk Benefit: Advancing the Science Through Expert Consensus. An Official American Thoracic Society Workshop Report. Annals Of The American Thoracic Society 2024 PMID: 39513996, DOI: 10.1513/annalsats.202409-981st.Peer-Reviewed Original ResearchObstructive sleep apneaPositive airway pressureRandomized controlled trialsCardiovascular diseaseImpact of obstructive sleep apneaPrevalence of obstructive sleep apneaOSA subtypesSubgroup of OSA patientsObstructive sleep apnea syndromeObstructive sleep apnea treatmentIncidence of comorbid conditionsSleep apnea treatmentCardiovascular risk benefitMulti-modality therapeutic approachSleep clinic patientsPersonalized therapeutic strategiesTreat symptomatic patientsResponse to treatmentSecondary CVD eventsCost-effective diagnosisComposite CVD outcomeOSA patientsPAP adherenceSleep apneaAssessment of symptoms
2007
Sleep Apnea and Stroke: A Risk Factor or an Association?
Yaggi H, Mohsenin V. Sleep Apnea and Stroke: A Risk Factor or an Association? Sleep Medicine Clinics 2007, 2: 583-591. DOI: 10.1016/j.jsmc.2007.07.004.Peer-Reviewed Original ResearchObstructive sleep apnea syndromeSleep apnea syndromeApnea syndromeSleep apneaPublic health implicationsDifferent study designsCardiovascular riskRisk factorsBiologic plausibilityEpidemiologic studiesTherapeutic impactStrokeStudy designHealth implicationsApneaSyndromeCurrent literatureAssociationDifferent populationsPathophysiology
2005
Obstructive Sleep Apnea as a Risk Factor for Stroke and Death
Yaggi HK, Concato J, Kernan WN, Lichtman JH, Brass LM, Mohsenin V. Obstructive Sleep Apnea as a Risk Factor for Stroke and Death. New England Journal Of Medicine 2005, 353: 2034-2041. PMID: 16282178, DOI: 10.1056/nejmoa043104.Peer-Reviewed Original ResearchConceptsObstructive sleep apnea syndromeSleep apnea syndromeApnea-hypopnea indexMean apnea-hypopnea indexRisk of strokeApnea syndromeRisk factorsSleep apneaComposite end pointObservational cohort studyObstructive sleep apneaProportional hazards analysisComparison groupAlcohol consumption statusBody mass indexImportant risk factorCohort studyComposite outcomeConsecutive patientsDiabetes mellitusSmoking statusAtrial fibrillationUnadjusted analysesSyndromePatients