2021
Increasing Prevalence of Critical Limb Ischemia Hospitalizations With Distinct Mental Health Burden Among Younger Adults
Harris KM, Mena-Hurtado C, Arham A, Burg MM, Freedland KE, Sinha R, Alabi O, Smolderen KG. Increasing Prevalence of Critical Limb Ischemia Hospitalizations With Distinct Mental Health Burden Among Younger Adults. Journal Of The American College Of Cardiology 2021, 78: 2126-2128. PMID: 34794693, DOI: 10.1016/j.jacc.2021.09.025.Peer-Reviewed Original Research
2018
Depression and long-term prognostic outcomes following peripheral endovascular interventions in the VA Healthcare System
Smolderen KG, Plomondon ME, Armstrong EJ, Hess E, Waldo S, Tsai TT, Maddox TM. Depression and long-term prognostic outcomes following peripheral endovascular interventions in the VA Healthcare System. Vascular Medicine 2018, 23: 454-460. PMID: 29801427, DOI: 10.1177/1358863x18770275.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAgedChi-Square DistributionComorbidityDepressionEndovascular ProceduresFemaleHumansHypertensionKaplan-Meier EstimateMaleMiddle AgedMyocardial InfarctionPeripheral Arterial DiseaseProportional Hazards ModelsRetrospective StudiesRisk FactorsStrokeTime FactorsTreatment OutcomeUnited StatesUnited States Department of Veterans AffairsConceptsNon-fatal cardiovascular eventsPeripheral vascular interventionsCardiovascular eventsDiagnosis of depressionHazard ratioMedical recordsAge-adjusted hazard ratioLong-term prognostic outcomesNon-fatal cardiovascular outcomesPeripheral endovascular interventionsLong-term outcomesPatients' medical recordsVA healthcare systemVeterans Affairs centersCause deathCardiovascular outcomesConsecutive patientsAdditional covariatesEndovascular interventionRecent diagnosisPrognostic outcomesDepressed patientsDisease outcomeVascular interventionsHigh riskAssociation between health status and sociodemographic, clinical and treatment disparities in the Patient-centered Outcomes Related to TReatment Practices in Peripheral Arterial Disease: Investigating Trajectories (PORTRAIT) registry
Noyes AM, Abbott JD, Gosch K, Smolderen K, Spertus JA, Hyder O, Soukas P, Shishehbor MH, Aronow HD. Association between health status and sociodemographic, clinical and treatment disparities in the Patient-centered Outcomes Related to TReatment Practices in Peripheral Arterial Disease: Investigating Trajectories (PORTRAIT) registry. Vascular Medicine 2018, 23: 32-38. PMID: 29338591, DOI: 10.1177/1358863x17747047.Peer-Reviewed Original ResearchConceptsPeripheral artery diseasePoor health statusIntermittent claudicationHealth statusPatient characteristicsDisease-specific health status measuresNon-vascular factorsPeripheral arterial diseaseChronic lung diseaseSpecialty care visitsTime of presentationHealth status measuresMultivariable linear regressionPatients' health statusQuality of lifeCare visitsArtery diseaseInitial presentationArterial diseaseBack painExercise programTreatment disparitiesLung diseaseFemale sexFunctional status
2015
Depressive Symptoms in Younger Women and Men With Acute Myocardial Infarction: Insights From the VIRGO Study
Smolderen KG, Strait KM, Dreyer RP, D'Onofrio G, Zhou S, Lichtman JH, Geda M, Bueno H, Beltrame J, Safdar B, Krumholz HM, Spertus JA. Depressive Symptoms in Younger Women and Men With Acute Myocardial Infarction: Insights From the VIRGO Study. Journal Of The American Heart Association 2015, 4: e001424. PMID: 25836055, PMCID: PMC4579927, DOI: 10.1161/jaha.114.001424.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionDepressive symptomsLifetime historyMyocardial infarctionRisk factorsYoung acute myocardial infarctionYoung AMI Patients (VIRGO) studyMore cardiovascular risk factorsYoung womenCardiovascular risk factorsTime of admissionAdverse medical outcomesMore depressive symptomsLow socioeconomic profileAMI severityVIRGO StudyCardiovascular riskChart abstractionYounger patientsClinical profileRelevant sex differencesPatient profilesAMI admissionsMedical outcomesPatients
2013
Preoperative Anxiety as a Predictor of Mortality and Major Morbidity in Patients Aged >70 Years Undergoing Cardiac Surgery
Williams JB, Alexander KP, Morin JF, Langlois Y, Noiseux N, Perrault LP, Smolderen K, Arnold SV, Eisenberg MJ, Pilote L, Monette J, Bergman H, Smith PK, Afilalo J. Preoperative Anxiety as a Predictor of Mortality and Major Morbidity in Patients Aged >70 Years Undergoing Cardiac Surgery. The American Journal Of Cardiology 2013, 111: 137-142. PMID: 23245838, PMCID: PMC3677723, DOI: 10.1016/j.amjcard.2012.08.060.Peer-Reviewed Original ResearchConceptsMajor morbidityCardiac surgeryHigh preoperative anxietyPreoperative anxietyHospital AnxietyDepression ScaleThoracic surgeonsProspective multicenter cohort studyMultivariable logistic regression analysisPatient-reported anxietyMulticenter cohort studyPredictors of mortalityTertiary care hospitalType of surgeryMain outcome measuresRisk of mortalityDepression Scale scoresPrimary predictor variableLogistic regression analysisPatients AgedPostoperative mortalityCause mortalityFrailty assessmentIndex hospitalizationCohort study
2012
Self-reported symptoms on questionnaires and anatomic lesions on duplex ultrasound examinations in patients with peripheral arterial disease
van Zitteren M, Vriens PW, Heyligers JM, Burger DH, Nooren MJ, de Fijter WM, Denollet J, Smolderen KG. Self-reported symptoms on questionnaires and anatomic lesions on duplex ultrasound examinations in patients with peripheral arterial disease. Journal Of Vascular Surgery 2012, 55: 1025-1034.e2. PMID: 22244858, DOI: 10.1016/j.jvs.2011.10.115.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsCross-Sectional StudiesFemaleFollow-Up StudiesHumansIntermittent ClaudicationLogistic ModelsLower ExtremityMaleMultivariate AnalysisOdds RatioPain MeasurementPeripheral Arterial DiseaseRisk FactorsSelf ReportSeverity of Illness IndexSurveys and QuestionnairesUltrasonography, Doppler, DuplexConceptsPeripheral arterial diseaseCardiovascular risk factorsDuplex ultrasound examinationDistal lesionsProximal lesionsLesion locationLeg symptomsPatient characteristicsSelf-reported symptomsArterial diseaseRisk factorsUltrasound examinationLower extremity peripheral arterial diseaseVascular surgery outpatient clinicMultivariable logistic regression analysisExertional leg symptomsNew-onset symptomsCardiovascular risk profileSurgery outpatient clinicMain outcome measuresCross-sectional studyFurther diagnostic imagingLogistic regression analysisTailor-made managementPAD subgroups
2010
Younger women with symptomatic peripheral arterial disease are at increased risk of depressive symptoms
Smolderen KG, Spertus JA, Vriens PW, Kranendonk S, Nooren M, Denollet J. Younger women with symptomatic peripheral arterial disease are at increased risk of depressive symptoms. Journal Of Vascular Surgery 2010, 52: 637-644. PMID: 20576397, DOI: 10.1016/j.jvs.2010.04.025.Peer-Reviewed Original ResearchMeSH KeywordsAdultAge FactorsAgedAged, 80 and overAnkle Brachial IndexDepressionFemaleHealth Status DisparitiesHumansIncidenceLogistic ModelsMaleMiddle AgedNetherlandsOdds RatioPeripheral Vascular DiseasesProspective StudiesPsychiatric Status Rating ScalesRegistriesRisk AssessmentRisk FactorsSex FactorsTime FactorsConceptsPeripheral arterial diseaseSignificant depressive symptomsDepressive symptomsGender-age groupsYoung womenArterial diseaseSymptomatic peripheral arterial diseaseEpidemiological Studies Depression ScaleFourfold greater oddsVascular outpatient clinicAnkle-brachial indexPatients' depressive symptomsTime of diagnosisLogistic regression modelsImportant comorbidityPAD diagnosisPAD patientsClinical factorsDepression screeningOutpatient clinicCardiovascular diseaseDepression riskDepression ScaleAdditional adjustmentGreater odds
2009
Impact of peripheral arterial disease on health status: A comparison with chronic heart failure
Smolderen KG, Pelle AJ, Kupper N, Mols F, Denollet J. Impact of peripheral arterial disease on health status: A comparison with chronic heart failure. Journal Of Vascular Surgery 2009, 50: 1391-1398. PMID: 19958988, DOI: 10.1016/j.jvs.2009.07.109.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAgedAmbulatory Care FacilitiesChronic DiseaseCost of IllnessCross-Sectional StudiesEducational StatusFemaleHeart DiseasesHeart FailureHumansLogistic ModelsMaleMarital StatusMental HealthMiddle AgedNetherlandsOdds RatioPeripheral Vascular DiseasesPropensity ScoreRisk AssessmentRisk FactorsSickness Impact ProfileConceptsPeripheral arterial diseaseChronic heart failurePhysical health statusMental health statusCHF patientsHealth statusPAD patientsCardiac historyDiabetes mellitusHeart failureArterial diseaseMedical recordsMedical conditionsImpact of PADLow ankle-brachial indexPatients' physical health statusYounger ageWorse physical health statusCross-sectional observational studyMental health status scoresComorbid diabetes mellitusAnkle-brachial indexClinical risk factorsHealth status scoresShort Form-12
2006
The 10-item Remembered Relationship with Parents (RRP10) scale: Two-factor model and association with adult depressive symptoms
Denollet J, Smolderen KG, van den Broek KC, Pedersen SS. The 10-item Remembered Relationship with Parents (RRP10) scale: Two-factor model and association with adult depressive symptoms. Journal Of Affective Disorders 2006, 100: 179-189. PMID: 17140669, DOI: 10.1016/j.jad.2006.10.009.Peer-Reviewed Original ResearchConceptsDepressive symptomsParental Bonding InstrumentPhysical healthCross-sectional study designRemembered RelationshipAdult depressive symptomsBeck Depression InventoryDysfunctional parenting stylesGood internal consistencyGeneral populationAdult depressionDepression InventorySymptomsClinical researchStudy designSignificant gender differencesEmpathic parentingConvergent validityInternal consistencyValid measureGender differencesParent scaleHealthHigh levelsControl