2000
Dependence of Oxygen Delivery on Blood Flow in Rat Brain: A 7 Tesla Nuclear Magnetic Resonance Study
Hyder F, Kennan R, Kida I, Mason G, Behar K, Rothman D. Dependence of Oxygen Delivery on Blood Flow in Rat Brain: A 7 Tesla Nuclear Magnetic Resonance Study. Cerebrovascular And Brain Metabolism Reviews 2000, 20: 485-498. PMID: 10724113, DOI: 10.1097/00004647-200003000-00007.Peer-Reviewed Original ResearchConceptsMagnetic resonance imagingCapillary bedOxygen deliveryML xCerebral oxygen deliveryNicotine hydrogen tartrateRespective control conditionsValues of CBFMorphine anesthesiaSensorimotor cortexForepaw stimulationSodium pentobarbitalRat brainBlood flowCMRO2Mature ratsCortical activityResonance imagingBasal conditionsPercentage changeRatsAdministrationCBF
1999
In vivo nuclear magnetic resonance spectroscopy studies of the relationship between the glutamate--glutamine neurotransmitter cycle and functional neuroenergetics
Rothman D, Sibson N, Hyder F, Shen J, Behar K, Shulman R. In vivo nuclear magnetic resonance spectroscopy studies of the relationship between the glutamate--glutamine neurotransmitter cycle and functional neuroenergetics. Philosophical Transactions Of The Royal Society B Biological Sciences 1999, 354: 1165-1177. PMID: 10466144, PMCID: PMC1692640, DOI: 10.1098/rstb.1999.0472.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsGlutamate-glutamine cycleNerve terminalsNeurotransmitter cycleGlucose metabolismBlood oxygenation level-dependent magnetic resonance imagingLevel-dependent magnetic resonance imagingBrain glucose oxidationCortical glucose metabolismMagnetic resonance spectroscopy studyCortex of ratsMagnetic resonance imagingFunctional imaging studiesSpecific neuronal activityOxidative glucose metabolismGlial cellsNeuronal activityResonance imagingImaging studiesHuman cortexBrain functionBrain activityRatsCortexGlucose oxidationGlutamate