1993
NMR-Spectroscopic Investigation of Cerebral Reanimation After Prolonged Ischemia
Hossmann K, Behar K, Rothman D. NMR-Spectroscopic Investigation of Cerebral Reanimation After Prolonged Ischemia. Acta Neurochirurgica Supplement 1993, 57: 21-29. PMID: 8421952, DOI: 10.1007/978-3-7091-9266-5_3.Peer-Reviewed Original ResearchConceptsHour complete ischemiaResidual blood flowBlood flowComplete ischemiaBrain injuryComplete recoveryBrain energy stateIrreversible brain injuryDuration of ischemiaAppropriate therapeutic measuresRise of lactatePost-ischemic injuryN-acetyl aspartateNon-invasive assessmentBrain glucose contentDepth of anesthesiaLower metabolite levelsBlood reperfusionIschemia timeReflow phenomenonBrain metabolismContinuous non-invasive assessmentProlonged ischemiaTherapeutic measuresIschemia
1989
NMR Spectroscopic Investigation of the Recovery of Energy and Acid—Base Homeostasis in the Cat Brain after Prolonged Ischemia
Behar K, Rothman D, Hossmann K. NMR Spectroscopic Investigation of the Recovery of Energy and Acid—Base Homeostasis in the Cat Brain after Prolonged Ischemia. Cerebrovascular And Brain Metabolism Reviews 1989, 9: 655-665. PMID: 2777935, DOI: 10.1038/jcbfm.1989.93.Peer-Reviewed Original ResearchEffects of Hypercarbia and Porta-Caval Shunting on Amino Acids and High Energy Phosphates of the Rat Brain: a 1H and 31P NMR Study
Behar K, Fitzpatrick S. Effects of Hypercarbia and Porta-Caval Shunting on Amino Acids and High Energy Phosphates of the Rat Brain: a 1H and 31P NMR Study. Experimental Biology And Medicine 1989, 189-200. DOI: 10.1007/978-1-4612-4506-3_13.Peer-Reviewed Original ResearchRat brainCerebral amino acidsEffects of hypercarbiaConcentration of glutamateHigh-energy phosphatesPorta-cavalCerebral hypoxiaMetabolic encephalopathiesHypercarbic acidosisAcute hyperammonemiaCerebral glutamateIntracellular acidosisEnergy phosphatesIncrease of glutamineHypercarbiaEncephalopathyAcidosisHyperammonemiaGlutamateBrainAmino acidsIntracellularIschemiaSeizuresShunting