2018
Monte Carlo dosimetry modeling of focused kV x‐ray radiotherapy of eye diseases with potential nanoparticle dose enhancement
Yan H, Ma X, Sun W, Mendez S, Stryker S, Starr‐Baier S, Delliturri G, Zhu D, Nath R, Chen Z, Roberts K, MacDonald CA, Liu W. Monte Carlo dosimetry modeling of focused kV x‐ray radiotherapy of eye diseases with potential nanoparticle dose enhancement. Medical Physics 2018, 45: 4720-4733. PMID: 30133705, DOI: 10.1002/mp.13144.Peer-Reviewed Original ResearchConceptsX-ray beamMC simulation programEye plaque treatmentCentral axis depth doseMC simulationsDose distributionBeam focusingEye Physics plaquesPhantom irradiationDose enhancementEnergy spectrumDepth doseLens modelingDosimetry modelingPhotoelectric absorptionKV rangeKV X-ray beamsBeamEBT3 filmSimulation programEnergy regimeModelingX-ray techniquesHalf maximumMore flexibility
2006
Potential impact of prostate edema on the dosimetry of permanent seed implants using the new (model CS‐1) seeds
Chen Z, Deng J, Roberts K, Nath R. Potential impact of prostate edema on the dosimetry of permanent seed implants using the new (model CS‐1) seeds. Medical Physics 2006, 33: 968-975. PMID: 16696473, DOI: 10.1118/1.2179170.Peer-Reviewed Original Research
2004
Optimization of dose distributions for bifurcated coronary vessels treated with catheter‐based photon and beta emitters using the simulated annealing algorithm
Yue N, Roberts KB, Son H, Khosravi S, Pfau SE, Nath R. Optimization of dose distributions for bifurcated coronary vessels treated with catheter‐based photon and beta emitters using the simulated annealing algorithm. Medical Physics 2004, 31: 2610-2622. PMID: 15487744, DOI: 10.1118/1.1783533.Peer-Reviewed Original ResearchMeSH KeywordsAlgorithmsAnimalsBeta ParticlesBlood Vessel ProsthesisBrachytherapyCatheterizationCatheters, IndwellingComputer SimulationCoronary RestenosisHumansModels, CardiovascularPhotonsRadiometryRadiotherapy DosageRadiotherapy Planning, Computer-AssistedRelative Biological EffectivenessReproducibility of ResultsSensitivity and SpecificityConceptsTreatment schemeCatheter-based delivery systemBetter dose distributionDose distributionDwell positionsPrescription doseCoronary vesselsBranch vesselsBranch treatmentBifurcation angleSatisfactory dose distributionMultiple dwell positionsVesselsOverdosingDelivery systemGeometry of bifurcationsEffects of vessel curvature on dose distributions in catheter-based intravascular brachytherapy for various radionuclides
Yue N, Roberts K, Nath R. Effects of vessel curvature on dose distributions in catheter-based intravascular brachytherapy for various radionuclides. Cardiovascular Revascularization Medicine 2004, 5: 142-150. PMID: 15721850, DOI: 10.1016/j.carrad.2004.08.002.Peer-Reviewed Original Research
2003
Dose distributions in bifurcated coronary vessels treated with catheter‐based photon and beta emitters in intravascular brachytherapy
Yue N, Roberts KB, Pfau SE, Nath R. Dose distributions in bifurcated coronary vessels treated with catheter‐based photon and beta emitters in intravascular brachytherapy. Medical Physics 2003, 30: 1628-1636. PMID: 12906180, DOI: 10.1118/1.1582813.Peer-Reviewed Original Research
2000
Dosimetric penumbra effects in catheter-based intravascular brachytherapy using a centered photon or beta line source.
Yue N, Nath R, Roberts K. Dosimetric penumbra effects in catheter-based intravascular brachytherapy using a centered photon or beta line source. Cardiovascular Revascularization Medicine 2000, 2: 32-8. PMID: 11229060.Peer-Reviewed Original ResearchConceptsLongitudinal dose uniformityCatheter-based intravascular brachytherapyRate kernelLine sourceCylindrical blood vesselPenumbra effectMonte Carlo simulationsBlood vesselsMargin lengthRadiation transportCarlo simulationsPhoton emittersEdge effectsRatio of doseDose distributionIntravascular brachytherapySource lengthRadial depthLength LRadioactive sourcesLinear sourceFormalismPhoton sourcesPoints of interestCorresponding radionuclide
1998
Correlation of medical dosimetry quality indicators to the local tumor control in patients with prostate cancer treated with iodine‐125 interstitial implants
Nath R, Roberts K, Ng M, Peschel R, Chen Z. Correlation of medical dosimetry quality indicators to the local tumor control in patients with prostate cancer treated with iodine‐125 interstitial implants. Medical Physics 1998, 25: 2293-2307. PMID: 9874821, DOI: 10.1118/1.598440.Peer-Reviewed Original ResearchConceptsSurvival rateProstate cancerInterstitial implantsLocal recurrence-free survival rateRecurrence-free survival ratesLocal control rateLocal tumor controlExcellent clinical resultsProstate cancer patientsUnfavorable groupClinical efficacyCancer patientsControl rateTumor controlClinical resultsFavorable groupDose coveragePatientsDosimetric parametersDosimetry parametersIsodose surfaceSignificant differencesVirginia studyUnfavorable parametersCancer