2023
In Vivo Verification of Electron Paramagnetic Resonance Biodosimetry Using Patients Undergoing Radiation Therapy Treatment
Draeger E, Roberts K, Decker R, Bahar N, Wilson L, Contessa J, Husain Z, Williams B, Flood A, Swartz H, Carlson D. In Vivo Verification of Electron Paramagnetic Resonance Biodosimetry Using Patients Undergoing Radiation Therapy Treatment. International Journal Of Radiation Oncology • Biology • Physics 2023, 119: 292-301. PMID: 38072322, DOI: 10.1016/j.ijrobp.2023.11.029.Peer-Reviewed Original ResearchHealthy volunteersDose rangeTotal body irradiationTotal body irradiation treatmentSignificant correlationRadiation therapy patientsPatient ageBody irradiationImmediate triageTherapy patientsClinical conditionsParticipants' teethPatientsNeck patientsUnknown dosesDosePatient dataRadiotherapy treatmentRadiation doseTeethTreatmentVolunteersSubsequent fractionsLuminescent dosimetersRadiation responsePredictors of Outcome for Allogeneic Stem Cell Transplantation with a Reduced Intensity Pentostatin/TBI Conditioning Regimen in T-Cell Lymphomas: A Single Center Experience
Hamouche R, Foss F, Mirza S, Di M, Isufi I, Bar N, Gowda L, Perreault S, Roberts K, Seropian S, Sethi T. Predictors of Outcome for Allogeneic Stem Cell Transplantation with a Reduced Intensity Pentostatin/TBI Conditioning Regimen in T-Cell Lymphomas: A Single Center Experience. Blood 2023, 142: 2172. DOI: 10.1182/blood-2023-189414.Peer-Reviewed Original ResearchT-cell lymphomaTotal body irradiationAggressive T-cell lymphomaReduced intensity conditioning regimenHematopoietic stem cell transplantationRefractory T-cell lymphomaNodal T-cell lymphomasIntensity conditioning regimenPotential curative optionStem cell transplantationConditioning regimenAdult patientsCurative optionRetrospective reviewBody irradiationCell transplantationSingle agentPatientsRegimenPentostatinAlloSCTTransplantationLymphomaACR–ARS Practice Parameter for the Performance of Total Body Irradiation
Reilly M, Dandapani S, Kumar K, Constine L, Fogh S, Roberts K, Small W, Schechter N. ACR–ARS Practice Parameter for the Performance of Total Body Irradiation. American Journal Of Clinical Oncology 2023, 46: 185-192. PMID: 36907934, DOI: 10.1097/coc.0000000000000997.Peer-Reviewed Original ResearchConceptsTotal body irradiationConventional total body irradiationBody irradiationPractice parametersAmerican Radium SocietyHigh-dose total body irradiationMean lung doseLung doseAmerican CollegeRadiation oncologistsClinical interestRadiation oncologyDose inhomogeneityACR websiteRadiation therapistsComprehensive updateTreatment planning systemOncologyPatient setupRotational techniqueAverage dose rateDose rateOngoing investigationOncologistsMedical physicists
2017
CNS Leukemia
An Y, Roberts K. CNS Leukemia. 2017, 311-333. DOI: 10.1007/978-3-319-55430-3_17.Peer-Reviewed Original ResearchAcute myeloid leukemiaAcute lymphoblastic leukemiaAllogeneic stem cell transplantCentral nervous system involvementPediatric acute lymphoblastic leukemiaInduction systemic therapyHigh-risk patientsNervous system involvementTotal body irradiationStem cell transplantUse of radiotherapyHigh cure ratesIntensity of therapyBlood-brain barrierCNS leukemiaCNS relapseCNS lymphomaPalliative therapySystemic therapyPrognostic factorsBody irradiationCell transplantRisk stratificationCure rateCommon cancer
2015
SU‐C‐BRD‐05: Non‐Invasive in Vivo Biodosimetry in Radiotherapy Patients Using Electron Paramagnetic Resonance (EPR) Spectroscopy
Bahar N, Roberts K, Stabile F, Mongillo N, Decker R, Wilson L, Husain Z, Contessa J, Williams B, Flood, Swartz H, Carlson D. SU‐C‐BRD‐05: Non‐Invasive in Vivo Biodosimetry in Radiotherapy Patients Using Electron Paramagnetic Resonance (EPR) Spectroscopy. Medical Physics 2015, 42: 3192-3193. DOI: 10.1118/1.4923800.Peer-Reviewed Original ResearchTotal body irradiationRadiotherapy patientsRadiation doseNeck radiotherapy patientsUpper central incisorsBiomedical Advanced ResearchBody irradiationFree radicalsFirst treatmentMedical interventionsEfficient triageCentral incisorsMedical countermeasuresPatientsDoseGyPreliminary dataHuman dataRetrospective biodosimetrySubsequent fractionsHuman ServicesInterventionLuminescent dosimetersMagnetic resonancePilot program
1999
Cyclophosphamide, cytosine arabinoside and TBI as a conditioning regimen for allogeneic bone marrow transplantation in patients with leukemia
Jillella A, Doria R, Khan K, Zelterman D, Ahmad Y, Smith B, Holmes W, Becker P, Roberts K, Rappeport J. Cyclophosphamide, cytosine arabinoside and TBI as a conditioning regimen for allogeneic bone marrow transplantation in patients with leukemia. Bone Marrow Transplantation 1999, 23: 1095-1100. PMID: 10382947, DOI: 10.1038/sj.bmt.1701786.Peer-Reviewed Original ResearchConceptsAllogeneic bone marrow transplantationTotal body irradiationBone marrow transplantationConditioning regimenMarrow transplantationMyeloablative regimenRelapse rateBody irradiationHematologic malignanciesAntileukemic effectGood prognosis diseaseHigh-dose cytosineHost disease (GVHD) prophylaxisShort-course methotrexateEvidence of diseaseOverall relapse rateHigh-dose AraPoor prognosis diseaseKaplan-Meier estimatesActuarial survivalConditioning regimensDisease prophylaxisMyeloablative regimensProspective studyRegimen