2013
Haplotype structure and positive selection at TLR1
Heffelfinger C, Pakstis AJ, Speed WC, Clark AP, Haigh E, Fang R, Furtado MR, Kidd KK, Snyder MP. Haplotype structure and positive selection at TLR1. European Journal Of Human Genetics 2013, 22: 551-557. PMID: 24002163, PMCID: PMC3953919, DOI: 10.1038/ejhg.2013.194.Peer-Reviewed Original ResearchConceptsToll-like receptor 2Toll-like receptor 1Missense variantsInnate immune systemReduced riskMedical conditionsReceptor 2Immune systemReceptor 1Cell surface receptorsSepsisSubsequent activationTLR1Surface receptorsBacterial lipoproteinsLeprosySurface traffickingDiseaseHuman healthRiskHealthMultiple functional allelesRs5743618TuberculosisLipoprotein
1987
Early Onset (Under Age 30 Years) and Panic Disorder as Markers for Etiologic Homogeneity in Major Depression
Price R, Kidd K, Weissman M. Early Onset (Under Age 30 Years) and Panic Disorder as Markers for Etiologic Homogeneity in Major Depression. JAMA Psychiatry 1987, 44: 434-440. PMID: 3472494, DOI: 10.1001/archpsyc.1987.01800170048008.Peer-Reviewed Original ResearchConceptsEarly onsetMajor depressionPanic disorderLate-onset depressionPrevalence of depressionElevation of riskFamilies of probandsYale Family StudyEtiologic homogeneityHigh riskPatterns of transmissionOlder age cohortsRestriction of analysisDepressionPopulation ratesFamily studiesProbandsOnsetDisordersAge cohortsRiskGenetic modelsSample sizeCohortPrevalence
1986
Understanding the Clinical Heterogeneity of Major Depression Using Family Data
Weissman M, Merikangas K, Priya W, Kidd K, Prusoff B, Leckman J, Pauls D. Understanding the Clinical Heterogeneity of Major Depression Using Family Data. JAMA Psychiatry 1986, 43: 430-434. PMID: 3964021, DOI: 10.1001/archpsyc.1986.01800050028003.Peer-Reviewed Original ResearchConceptsMajor depressionSymptom patternsHistory of hospitalizationClinical presentationClinical severityRecurrent depressionSecondary alcoholismClinical heterogeneitySuicidal ideationAnxiety disordersDepressionFamilial aggregationEarly ageDisordersCombination of criteriaAgeSubgroupsRiskOnsetPutative subgroupsHospitalization
1984
The Risk of Tourette's Syndrome and Chronic Multiple Tics among Relatives of Tourette's Syndrome Patients Obtained by Direct Interview
PAULS D, KRUGER S, LECKMAN J, COHEN D, KIDD K. The Risk of Tourette's Syndrome and Chronic Multiple Tics among Relatives of Tourette's Syndrome Patients Obtained by Direct Interview. Journal Of The American Academy Of Child & Adolescent Psychiatry 1984, 23: 134-137. PMID: 6585415, DOI: 10.1097/00004583-198403000-00003.Peer-Reviewed Original ResearchPsychopathology in the Children (Ages 6–18) of Depressed and Normal Parents
WEISSMAN M, PRUSOFF B, GAMMON G, MERIKANGAS K, LECKMAN J, KIDD K. Psychopathology in the Children (Ages 6–18) of Depressed and Normal Parents. Journal Of The American Academy Of Child & Adolescent Psychiatry 1984, 23: 78-84. PMID: 6693680, DOI: 10.1097/00004583-198401000-00011.Peer-Reviewed Original ResearchConceptsDSM-III diagnosesFirst-degree relativesMajor depressionPsychiatric disordersProbands' first-degree relativesChildren of probandsCommon psychiatric disordersDirect interview studyFamily history studyClinical statusPsychiatric illnessNormal controlsDepressed probandsPsychological symptomsSuicidal behaviorEarly onsetDiagnosisDepressionSignificant predictorsProbandsAttention deficitsChildrenRiskEmotional problemsNormal parents