2022
Performance of IRBs in China: a survey on IRB employees and researchers’ experiences and perceptions
Liu X, Wu Y, Yang M, Li Y, Khoshnood K, Luo E, Li L, Wang X. Performance of IRBs in China: a survey on IRB employees and researchers’ experiences and perceptions. BMC Medical Ethics 2022, 23: 89. PMID: 36038889, PMCID: PMC9426015, DOI: 10.1186/s12910-022-00826-4.Peer-Reviewed Original ResearchKnowledge of mental health diagnosis among patients and their family members: an inpatient survey in China
Zhou W, Ouyang F, Yu Y, Li Y, Bi F, Xiao S, Khoshnood K. Knowledge of mental health diagnosis among patients and their family members: an inpatient survey in China. Journal Of Mental Health 2022, 32: 234-240. PMID: 35770867, DOI: 10.1080/09638237.2022.2091753.Peer-Reviewed Original ResearchConceptsMental health diagnosesNon-psychotic disordersNational Mental Health LawHealth diagnosisInpatient SurveyPsychotic disordersMental disordersSelf-reported mental health diagnosesFamily membersMajority of patientsMultivariate regression analysisRisk factorsCorrect diagnosisPatientsPsychiatric settingsPatient diagnosisLogistic regressionDiagnosisDiagnostic disclosureMental health lawDisordersGroup differencesRegression analysisHealth lawEthical Decision-making of Health Professionals Caring for People Living with HIV/AIDS in Hunan, China: A Qualitative Study
Lu X, Huang H, Khoshnood K, Koniak-Griffin D, Wang H, Yang M. Ethical Decision-making of Health Professionals Caring for People Living with HIV/AIDS in Hunan, China: A Qualitative Study. INQUIRY The Journal Of Health Care Organization Provision And Financing 2022, 59: 00469580221127789. PMID: 36444995, PMCID: PMC9716589, DOI: 10.1177/00469580221127789.Peer-Reviewed Original ResearchConceptsEthical dilemmasEthical judgmentsEthical decision-making (EDM) processReal ethical dilemmasNumerous ethical issuesEthical behaviorProfessional codesEthical issuesEthical motivationHealth professionalsHIV/AIDSProfessional caringDescriptive qualitative researchDilemmaClinical practiceQualitative researchJudgmentsPeople's interestHealth Professionals CaringMedical disputesImmunodeficiency syndromeProfessionalsIssuesDecision making processPractice
2021
Cross-cultural validation of the IRB Researcher Assessment Tool: Chinese Version
Liu X, Wu Y, Yang M, Li Y, Hahne J, Khoshnood K, Coleman L, Wang X. Cross-cultural validation of the IRB Researcher Assessment Tool: Chinese Version. BMC Medical Ethics 2021, 22: 133. PMID: 34583718, PMCID: PMC8479956, DOI: 10.1186/s12910-021-00699-z.Peer-Reviewed Original ResearchDeveloping Quality and Efficiency of Institutional Review Board Review Under a Human Research Protection Program at a Leading Hospital in Central Southern China: A Descriptive Analysis of the First Three Years
Wang X, Hahne J, Li L, Khoshnood K, Yang G, Yuan H, Liu X. Developing Quality and Efficiency of Institutional Review Board Review Under a Human Research Protection Program at a Leading Hospital in Central Southern China: A Descriptive Analysis of the First Three Years. Journal Of Empirical Research On Human Research Ethics 2021, 16: 280-289. PMID: 33729908, PMCID: PMC8238789, DOI: 10.1177/1556264621995656.Peer-Reviewed Original Research
2020
Interpersonal factors contributing to tension in the Chinese doctor–patient–family relationship: a qualitative study in Hunan Province
Xiao S, Wang L, Edelman EJ, Khoshnood K. Interpersonal factors contributing to tension in the Chinese doctor–patient–family relationship: a qualitative study in Hunan Province. BMJ Open 2020, 10: e040743. PMID: 33303452, PMCID: PMC7733169, DOI: 10.1136/bmjopen-2020-040743.Peer-Reviewed Original ResearchGender Differences in Attitudes Toward Death Among Chinese College Students and the Implications for Death Education Courses
Wang Y, Tang S, Hu X, Qin C, Khoshnood K, Sun M. Gender Differences in Attitudes Toward Death Among Chinese College Students and the Implications for Death Education Courses. OMEGA - Journal Of Death And Dying 2020, 85: 59-74. PMID: 32580650, DOI: 10.1177/0030222820934944.Peer-Reviewed Original Research
2019
Breaking bad news about cancer in China: Concerns and conflicts faced by doctors deciding whether to inform patients
Hahne J, Liang T, Khoshnood K, Wang X, Li X. Breaking bad news about cancer in China: Concerns and conflicts faced by doctors deciding whether to inform patients. Patient Education And Counseling 2019, 103: 286-291. PMID: 31455567, DOI: 10.1016/j.pec.2019.08.022.Peer-Reviewed Original Research
2018
Quality of life in HIV-infected Chinese women and their family caregivers:an intervention study
Chen WT, Shiu C, Yang JP, Wang K, Zhang L, Zhang J, Reynolds NR, Kennedy HP, Khoshnood K, Chen LC, Bao M, Zhao H, Lu H. Quality of life in HIV-infected Chinese women and their family caregivers:an intervention study. AIDS Care 2018, 30: 1572-1579. PMID: 30111163, PMCID: PMC6287628, DOI: 10.1080/09540121.2018.1510095.Peer-Reviewed Original ResearchConceptsChinese HIVIntervention armDepressive symptomatologyPhysical QoLFamily caregiversNumber of HIVQuality of lifeHigher physical QoLHIV managementMonth 3Large trialsNurse interventionistControl armMonths 1HIVIntervention studiesPreliminary effectsChinese womenChinese hospitalsWomenCaregiversSymptomatologyCounseling sessionsInterventionSelf-report surveyHIV-related stigma among people living with HIV/AIDS in rural Central China
Li Z, Morano JP, Khoshnood K, Hsieh E, Sheng Y. HIV-related stigma among people living with HIV/AIDS in rural Central China. BMC Health Services Research 2018, 18: 453. PMID: 29903006, PMCID: PMC6003113, DOI: 10.1186/s12913-018-3245-0.Peer-Reviewed Original ResearchConceptsHIV/AIDSRural PLWHAYoung PLWHAOpportunistic infectionsBerger HIV Stigma ScaleMethodsA cross-sectional studyMultivariable linear regression analysisBurden of HIVDisease-related factorsLevels of HIVCross-sectional studyHIV Stigma ScaleTotal HIVResultsA totalRural central ChinaPoor adherenceChinese PLWHAHIV stigmaHIVPLWHAChinese CenterStigma scoresLinear regression analysisStigma ScaleHigh levels
2017
The Ethical Sensitivity of Health Care Professionals Who Care For Patients Living With HIV Infection in Hunan, China: A Qualitative Study
Huang H, Ding Y, Wang H, Khoshnood K, Yang M. The Ethical Sensitivity of Health Care Professionals Who Care For Patients Living With HIV Infection in Hunan, China: A Qualitative Study. Journal Of The Association Of Nurses In AIDS Care 2017, 29: 266-274. PMID: 28967489, PMCID: PMC5816692, DOI: 10.1016/j.jana.2017.09.001.Peer-Reviewed Original ResearchConceptsEthical sensitivityEthical issuesHealth care professionalsEthical behaviorEthical principlesCare professionalsSuch professionalsCertain sensitivityHIV careHIV infectionEthicsHIVClinical practicePatientsProfessionalsDirect careQualitative descriptive studyIssuesDescriptive studyLawCareAttitudesQualitative studyPrinciplesInterview transcriptsNurse researchers’ perspectives on research ethics in China
Gu C, Ye M, Wang X, Yang M, Wang H, Khoshnood K. Nurse researchers’ perspectives on research ethics in China. Nursing Ethics 2017, 26: 798-808. PMID: 28812946, DOI: 10.1177/0969733017720848.Peer-Reviewed Original ResearchConceptsResearch ethicsEthical standardsResearchers' viewsInstitutional review board membersNursing researchersInstitutional review boardComprehensive ethical guidelinesEthics review processPerceptions of ethicsReview board membersReview boardQualitative research methodsEthical paradigmsEthical challengesEthical guidelinesEthical principlesEthicsFormal regulationsResearch contextChinese contextNurse researchersIntensive educational effortsInterviewees' responsesResearcher's perspectiveYale University
2016
Cross-cultural validation of the moral sensitivity questionnaire-revised Chinese version
Huang FF, Yang Q, Zhang J, Zhang QH, Khoshnood K, Zhang JP. Cross-cultural validation of the moral sensitivity questionnaire-revised Chinese version. Nursing Ethics 2016, 23: 784-793. PMID: 26002939, DOI: 10.1177/0969733015583183.Peer-Reviewed Original ResearchConceptsMoral Sensitivity QuestionnaireEthical sensitivitySensitivity QuestionnaireTranslation validity indexMoral responsibilityEthical issuesMoral burdenBest interestsResearch contextInstitutional review boardChinese nursesYale UniversityReview boardItem-total correlation valuesBrislin's modelDaily practiceChinese languageComplicated situationsMeaningful implicationsResponsibilityEmpirical studySenseNursesVersionIssuesChinese nurses’ perceived barriers and facilitators of ethical sensitivity
Huang FF, Yang Q, Zhang J, Khoshnood K, Zhang JP. Chinese nurses’ perceived barriers and facilitators of ethical sensitivity. Nursing Ethics 2016, 23: 507-522. PMID: 25825415, DOI: 10.1177/0969733015574925.Peer-Reviewed Original ResearchConceptsEthical sensitivityMoral Sensitivity QuestionnaireEthical issuesSensitivity QuestionnaireCultural environmentConvergent parallel mixed-methods research designEthical knowledgeParallel mixed-methods research designNurses' sensitivityResearch contextInstitutional review boardChinese nursesWorking attitudeEthicsYale UniversityReview boardIssuesPracticeOrganizational climateKey demographicsNurses' perceptionsVersion scoresExperienceNursesAttitudes
2015
Causes of Death among AIDS Patients after Introduction of Free Combination Antiretroviral Therapy (cART) in Three Chinese Provinces, 2010–2011
Wang L, Ge L, Wang L, Morano JP, Guo W, Khoshnood K, Qin Q, Ding Z, Sun D, Liu X, Luo H, Tillman J, Cui Y. Causes of Death among AIDS Patients after Introduction of Free Combination Antiretroviral Therapy (cART) in Three Chinese Provinces, 2010–2011. PLOS ONE 2015, 10: e0139998. PMID: 26506621, PMCID: PMC4624241, DOI: 10.1371/journal.pone.0139998.Peer-Reviewed Original ResearchConceptsCombination antiretroviral therapyCause of deathCells/mm3AIDS patientsCD4 countCombination anti-retroviral therapyDeceased AIDS patientsNational HIV RegistryAnti-retroviral therapyInjury-related deathsCross-sectional surveyCause of AIDSCART initiationHIV RegistryAntiretroviral therapyART-naïveHIV diagnosisDisease burdenMedical recordsChi-square analysisAverage agePatientsART statusLogistic regressionAIDSEvaluating the Impact of Test-and-Treat on the HIV Epidemic among MSM in China Using a Mathematical Model
Luo S, Han L, Lu H, Dou Z, Tao Q, Khoshnood K, Wu Z, Xu J. Evaluating the Impact of Test-and-Treat on the HIV Epidemic among MSM in China Using a Mathematical Model. PLOS ONE 2015, 10: e0126893. PMID: 26039075, PMCID: PMC4454496, DOI: 10.1371/journal.pone.0126893.Peer-Reviewed Original ResearchHuman Immunodeficiency Virus Infection-Associated Mortality during Pulmonary Tuberculosis Treatment in Six Provinces of China.
Lai YJ, Liu EY, Wang LM, Morano JP, Wang N, Khoshnood K, Zhou L, Cheng SM. Human Immunodeficiency Virus Infection-Associated Mortality during Pulmonary Tuberculosis Treatment in Six Provinces of China. Biomedical And Environmental Sciences 2015, 28: 421-8. PMID: 26177902, DOI: 10.3967/bes2015.059.Peer-Reviewed Original ResearchConceptsRisk factorsMiliary TBTB treatmentHuman immunodeficiency virus (HIV) infection epidemicSignificant mortality risk factorsAntiretroviral therapy administrationEarly TB diagnosisLow CD4 countSmear-negative TBTB treatment initiationTuberculosis-related deathsPulmonary TB patientsTB/HIVProspective cohort studyImmunodeficiency syndrome (AIDS) patientsTime of diagnosisMortality risk factorsPulmonary tuberculosis treatmentRisk of deathNumber of HIVStrong risk factorLogistic regression analysisYears of ageNon-Han ethnicityCD4 countKnowledge and perceptions of sexual and reproductive health and HIV among perinatally HIV-infected adolescents in rural China
Mu W, Zhao Y, Khoshnood K, Cheng Y, Sun X, Liu X, Xu W, Wang S, Ma Y, Zhang F. Knowledge and perceptions of sexual and reproductive health and HIV among perinatally HIV-infected adolescents in rural China. AIDS Care 2015, 27: 1137-1142. PMID: 25894204, DOI: 10.1080/09540121.2015.1032206.Peer-Reviewed Original ResearchConceptsHIV knowledgeReproductive healthDescriptive cross-sectional studyRural HIV clinicActive antiretroviral therapyHIV treatment programsMultivariable logistic regressionCross-sectional studyLong-term careAntiretroviral therapyHIV clinicHIV statusMedical visitsSRH servicesAdult careComprehensive carePuberty developmentEarly deathHIVPsychosocial supportTreatment programLogistic regressionVulnerable populationsMore childrenPHIVABridging the Epidemic: A Comprehensive Analysis of Prevalence and Correlates of HIV, Hepatitis C, and Syphilis, and Infection among Female Sex Workers in Guangxi Province, China
Chen Y, Shen Z, Morano JP, Khoshnood K, Wu Z, Lan G, Zhu Q, Zhou Y, Tang S, Liu W, Chen J, Tang Z. Bridging the Epidemic: A Comprehensive Analysis of Prevalence and Correlates of HIV, Hepatitis C, and Syphilis, and Infection among Female Sex Workers in Guangxi Province, China. PLOS ONE 2015, 10: e0115311. PMID: 25723548, PMCID: PMC4344209, DOI: 10.1371/journal.pone.0115311.Peer-Reviewed Original ResearchConceptsLow-tier female sex workersFemale sex workersSentinel surveillance dataHepatitis CSurveillance dataCorrelates of HIVIntravenous drug useHeterosexual HIV epidemicPrevalence of HIVSex workersHarm reduction campaignsLogistic regression analysisLow formal education levelLow-tier venuesSafer sex practicesHCV prevalencePrior STIHCV infectionSyphilis infectionSyphilis prevalenceRisk factorsHIV epidemicCondom distributionHCVHigh riskPrognosis-related factors in intensive care unit (ICU) patients with hematological malignancies: A retrospective cohort analysis in a Chinese population
Liu J, Cheng Q, Yang Q, Li X, Shen X, Zhang L, Liu Z, Khoshnood K. Prognosis-related factors in intensive care unit (ICU) patients with hematological malignancies: A retrospective cohort analysis in a Chinese population. Hematology 2015, 20: 494-503. PMID: 25585045, DOI: 10.1179/1607845414y.0000000216.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overAntineoplastic AgentsAPACHEChinaFemaleHematologic NeoplasmsHospitals, UniversityHumansIntensive Care UnitsMaleMiddle AgedPrognosisRespiration, ArtificialRespiratory InsufficiencyRetrospective StudiesRisk FactorsSeverity of Illness IndexSurvival AnalysisConceptsSequential Organ Failure AssessmentInvasive mechanical ventilationHematological malignanciesUse of IMVDetailed retrospective chart reviewIntensive care unit admissionIntensive care unit patientsLong-term mortality ratesCare unit admissionChronic Health EvaluationOrgan Failure AssessmentRetrospective chart reviewRetrospective cohort analysisCare unit patientsPrognosis-related factorsUniversity-affiliated hospitalIntensive care resourcesStrong predictive valuePanel of parametersAcute PhysiologyAdverse predictorsIMV useSOFA scoreUnit admissionICU mortality