Featured Publications
Full facial retransplantation in a female patient—Technical, immunologic, and clinical considerations
Kauke M, Panayi AC, Safi A, Haug V, Perry B, Kollar B, Nizzi M, Broyles J, Annino DJ, Marty FM, Sinha I, Lian CG, Murphy GF, Chandraker A, Pomahac B. Full facial retransplantation in a female patient—Technical, immunologic, and clinical considerations. American Journal Of Transplantation 2021, 21: 3472-3480. PMID: 34033210, DOI: 10.1111/ajt.16696.Peer-Reviewed Original ResearchConceptsChronic antibody-mediated rejectionPatient underwent retransplantationRecurrent cellular rejectionAntibody-mediated rejectionImmediate postoperative phaseInterposition vein graftAllograft lossCellular rejectionFirst allograftOlder allograftsRejection episodesUnderwent retransplantationSecond transplantationFirst transplantPostoperative outcomesAllotransplant recipientsPostoperative phaseVein graftsHyperacute rejectionFacial nerveOutcomes 6Arterial anastomosisRetransplantationSurgical techniquePsychosocial management
2024
Risk Factors and Outcomes after Surgery for Malignant Neoplasm of the Parotid Gland: An ACS-NSQIP Study
Knoedler L, Knoedler S, Hoch C, Safi A, Wollenberg B, Alfertshofer M, Pomahac B, Kauke-Navarro M, Clune J. Risk Factors and Outcomes after Surgery for Malignant Neoplasm of the Parotid Gland: An ACS-NSQIP Study. Journal Of Plastic Reconstructive & Aesthetic Surgery 2024 PMID: 39448324, DOI: 10.1016/j.bjps.2024.09.067.Peer-Reviewed Original ResearchBlood urea nitrogenRisk factorsRenal failureParotid glandMalignant neoplasmsAmerican College of Surgeons National Surgical Quality Improvement Program databaseSurgeons National Surgical Quality Improvement Program databaseAssociated with higher creatinineNational Surgical Quality Improvement Program databaseMicrosurgical proceduresPre-operative risk factorsQuality Improvement Program databaseRisk of postoperative adverse eventsBlood urea nitrogen levelsHigher ASA classPostoperative adverse eventsOccurrence of complicationsPost-surgical outcomesTumor resectionComplication rateFlap surgeryPostoperative outcomesACS-NSQIPASA classHigher creatinineThe impact of age on outcomes after breast reduction surgery – A multi-institutional data analysis of 40,958 cases
Knoedler S, Perozzo F, Jiang J, Kosyk M, Alfertshofer M, Schenck T, Kern B, Sofo G, Knoedler L, Panayi A, Pomahac B, Kauke-Navarro M, Kim B. The impact of age on outcomes after breast reduction surgery – A multi-institutional data analysis of 40,958 cases. Journal Of Plastic Reconstructive & Aesthetic Surgery 2024, 98: 318-330. PMID: 39321535, DOI: 10.1016/j.bjps.2024.09.027.Peer-Reviewed Original ResearchReduction mammoplastyFemale patientsMedical complicationsImpact of ageAmerican College of Surgeons National Surgical Quality Improvement ProgramSurgeons National Surgical Quality Improvement ProgramNational Surgical Quality Improvement ProgramSurgical Quality Improvement ProgramPatients aged <Patients aged >Breast reduction surgeryAdult female patientsQuality Improvement ProgramPostoperative morbiditySurgical complicationsPostoperative outcomesPatient ageReduction surgeryDeterminants of riskMultivariate analysisAmerican CollegeComplicationsLow riskPatientsMammoplastyTurn Your Vision into Reality—AI-Powered Pre-operative Outcome Simulation in Rhinoplasty Surgery
Knoedler S, Alfertshofer M, Simon S, Panayi A, Saadoun R, Palackic A, Falkner F, Hundeshagen G, Kauke-Navarro M, Vollbach F, Bigdeli A, Knoedler L. Turn Your Vision into Reality—AI-Powered Pre-operative Outcome Simulation in Rhinoplasty Surgery. Aesthetic Plastic Surgery 2024, 1-6. PMID: 38777929, DOI: 10.1007/s00266-024-04043-9.Peer-Reviewed Original ResearchRhinoplasty surgeryRhinoplasty outcomesLevel of Evidence IIIThis journalEvidence-Based Medicine ratingsStudy participantsEvidence IIIThis journalLevel of evidencePre-operative consultationManaging patient expectationsResultsThe study sampleFemale study participantsPostoperative imagingPostoperative outcomesPatient photographsRhinoplasty patientsMale study participantsRhinoplastyPatient imagesPatient expectationsSurgeryGAN-generated imagesEffective doctor-patient communicationOnline InstructionsOutcomesDoctor-patient communicationIsolated and combined breast augmentation in transgender patients: Multi-institutional insights into early outcomes and risk factors
Knoedler S, Knoedler L, Geldner B, Ghanad I, Kim B, Alfertshofer M, Machens H, Broer P, Pomahac B, Kauke-Navarro M, Paik A. Isolated and combined breast augmentation in transgender patients: Multi-institutional insights into early outcomes and risk factors. Journal Of Plastic Reconstructive & Aesthetic Surgery 2024, 90: 149-160. PMID: 38367411, DOI: 10.1016/j.bjps.2024.01.026.Peer-Reviewed Original ResearchBreast augmentation surgeryNational Surgical Quality Improvement ProgramBody mass indexGender-affirming surgeryAmerican College of SurgeonsAdverse eventsAmerican Society of Anesthesiology class 1Advanced ageEvaluate 30-day outcomesRisk factorsSurgical Quality Improvement ProgramPositive safety profileSurgical decision-makingNo adverse eventsIncidence of mortalityIdentified risk factorsCombined surgeryQuality Improvement ProgramGenitourinary proceduresGenitourinary surgeryNicotine abuseAugmentation surgeryBreast augmentationComplication ratePostoperative outcomes
2023
Surgical management of breast fat necrosis: Multi-institutional data analysis of early outcomes and risk factors for complications
Knoedler S, Knoedler L, Patel H, Diatta F, Camacho J, Sofo G, Perozzo F, Evans B, Mookerjee V, Ayyala H, Pomahac B, Kauke-Navarro M. Surgical management of breast fat necrosis: Multi-institutional data analysis of early outcomes and risk factors for complications. Journal Of Plastic Reconstructive & Aesthetic Surgery 2023, 88: 292-295. PMID: 38029475, DOI: 10.1016/j.bjps.2023.11.015.Peer-Reviewed Original ResearchConceptsBreast fat necrosisChronic heart failureRisk factorsAdverse eventsHeart failureFemale patientsSurgical managementFat necrosisNational Surgical Quality Improvement ProgramSurgical Quality Improvement ProgramHigher wound classPostoperative adverse eventsNon-cancerous conditionsOutcomes of interestQuality Improvement ProgramMajority of casesPerioperative algorithmWound classComplication occurrenceComplication ratePostoperative outcomesSurgical complicationsMedical complicationsSurgical treatmentMultivariable analysisAn ACS-NSQIP Data Analysis of 30-Day Outcomes Following Surgery for Bell’s Palsy
Knoedler S, Knoedler L, Hoch C, Kauke-Navarro M, Kehrer A, Friedman L, Prantl L, Machens H, Orgill D, Panayi A. An ACS-NSQIP Data Analysis of 30-Day Outcomes Following Surgery for Bell’s Palsy. Journal Of Craniofacial Surgery 2023, 35: 23-28. PMID: 37695075, PMCID: PMC10841222, DOI: 10.1097/scs.0000000000009739.Peer-Reviewed Original ResearchBell's palsyHospital stayPostoperative outcomesSurgeons National Surgical Quality Improvement Program databaseNational Surgical Quality Improvement Program databaseFuture large-scale prospective studiesDiagnosis of BPQuality Improvement Program databaseLarge-scale prospective studiesImprovement Program databasePoor postoperative outcomesRoutine laboratory valuesOutcome of surgeryMulti-institutional analysisBlood urea nitrogenMulti-institutional databaseMajority of proceduresMulti-institutional studyQuality of careCommon comorbiditiesFrequent complicationPerioperative protocolComplication rateMedical complicationsPreoperative evaluationImpact of sarcopenia on outcomes in surgical patients: a systematic review and meta-analysis
Knoedler S, Schliermann R, Knoedler L, Wu M, Hansen F, Matar D, Obed D, Vervoort D, Haug V, Hundeshagen G, Paik A, Kauke-Navarro M, Kneser U, Pomahac B, Orgill D, Panayi A. Impact of sarcopenia on outcomes in surgical patients: a systematic review and meta-analysis. International Journal Of Surgery 2023, 109: 4238-4262. PMID: 37696253, PMCID: PMC10720826, DOI: 10.1097/js9.0000000000000688.Peer-Reviewed Original ResearchImpact of sarcopeniaPostoperative outcomesComplication occurrenceSurgical patientsSystematic reviewHospital stayPrognostic valueSubgroup analysisSurvival rateClavien-Dindo classification systemImportance of sarcopeniaFrequency of complicationsPoor postoperative outcomesInflammatory bowel diseaseSignificant predictorsHigh-quality studiesMeta-Analyses (PRISMA) guidelinesProspective study designPubMed/MEDLINESkeletal muscle massPreferred Reporting ItemsLength of operationLower survival rateSarcopenic patientsPerioperative riskIncidence and Risk Factors of Postoperative Complications After Rhinoplasty: A Multi-Institutional ACS-NSQIP Analysis
Knoedler S, Knoedler L, Wu M, Haug V, Broer P, Kauke-Navarro M, Hundeshagen G, Prantl L, Orgill D, Panayi A. Incidence and Risk Factors of Postoperative Complications After Rhinoplasty: A Multi-Institutional ACS-NSQIP Analysis. Journal Of Craniofacial Surgery 2023, 34: 1722-1726. PMID: 37487058, DOI: 10.1097/scs.0000000000009553.Peer-Reviewed Original ResearchConceptsLow serum albuminSurgical adverse eventsAdverse eventsRisk factorsPostoperative outcomesASA scoreComplication rateMale sexSurgeons National Surgical Quality Improvement Program databaseNational Surgical Quality Improvement Program databaseQuality Improvement Program databasePreoperative nutritional optimizationSuperficial incisional infectionAverage patient ageHigher ASA scoreImprovement Program databasePreoperative laboratory valuesACS-NSQIP AnalysisMulti-institutional analysisSingle-institution reportsIncisional infectionPostoperative complicationsPreoperative albuminComplication occurrenceMost patients
2022
30-Day Postoperative Outcomes in Adults with Obstructive Sleep Apnea Undergoing Upper Airway Surgery
Knoedler S, Knoedler L, Baecher H, Kauke-Navarro M, Obed D, Hoch C, Diehm Y, Vosler P, Harréus U, Kneser U, Panayi A. 30-Day Postoperative Outcomes in Adults with Obstructive Sleep Apnea Undergoing Upper Airway Surgery. Journal Of Clinical Medicine 2022, 11: 7371. PMID: 36555986, PMCID: PMC9783895, DOI: 10.3390/jcm11247371.Peer-Reviewed Original ResearchObstructive sleep apneaOSA surgeryPostoperative outcomesMedical complicationsSleep apneaSurgeons National Surgical Quality Improvement Program databaseNational Surgical Quality Improvement Program databaseMulti-institutional national databaseQuality Improvement Program databaseUpper airway surgeryTotal complication rateHistory of diabetesImprovement Program databasePositive safety profileAlkaline phosphatasePostoperative complicationsComplication ratePostoperative periodAirway surgeryFrequent comorbiditiesMale sexSafety profileUpper airwaySurgery outcomesChronic disordersPerioperative Outcomes and Risk Profile of 4730 Cosmetic Breast Surgery Cases in Academic Institutions: An ACS-NSQIP Analysis
Knoedler S, Kauke-Navarro M, Haug V, Broer P, Pomahac B, Knoedler L, Panayi A. Perioperative Outcomes and Risk Profile of 4730 Cosmetic Breast Surgery Cases in Academic Institutions: An ACS-NSQIP Analysis. Aesthetic Surgery Journal 2022, 43: 433-451. PMID: 36472232, DOI: 10.1093/asj/sjac320.Peer-Reviewed Original ResearchConceptsChronic obstructive pulmonary diseaseCosmetic breast surgeryObstructive pulmonary diseaseRisk factorsSurgical complicationsPulmonary diseaseSurgeons National Surgical Quality Improvement Program databaseNational Surgical Quality Improvement Program databaseMulti-institutional national databaseMultiple proceduresQuality Improvement Program databaseImprovement Program databaseIndependent risk factorCongestive heart failurePositive safety profileObesity class 1ACS-NSQIP AnalysisAnesthesiology scoreBreast surgery casesPerioperative outcomesPerioperative protocolPostoperative outcomesClinical patternHeart failureFemale patientsThe modified 5-item frailty index is a predictor of perioperative risk in breast reconstruction: An analysis of 40,415 cases
Panayi AC, Foroutanjazi S, Parikh N, Haug V, Kauke-Navarro M, Diehm YF, Pomahac B. The modified 5-item frailty index is a predictor of perioperative risk in breast reconstruction: An analysis of 40,415 cases. Journal Of Plastic Reconstructive & Aesthetic Surgery 2022, 75: 2941-2954. PMID: 35599223, DOI: 10.1016/j.bjps.2022.04.035.Peer-Reviewed Original ResearchConceptsImplant-based reconstructionBreast reconstructionMFI-5Unplanned readmissionPostoperative outcomesSurgical complicationsMedical complicationsMFI scoreRisk predictorsSurgeons National Surgical Quality Improvement Program databaseNational Surgical Quality Improvement Program databaseQuality Improvement Program databaseBreast reconstruction patientsFrailty index-5Powerful risk predictorImprovement Program databasePreoperative risk stratificationStrong risk predictorAutologous breast reconstructionAdverse surgical outcomesType of reconstructionHigh rateFrail patientsHospital stayPerioperative riskRacial disparities in short-term outcomes after breast reduction surgery–A National Surgical Quality Improvement Project Analysis with 23,268 patients using Propensity Score Matching
Haug V, Kadakia N, Wang AT, Dorante MI, Panayi AC, Kauke-Navarro M, Hundeshagen G, Diehm YF, Fischer S, Hirche C, Kneser U, Pomahac B. Racial disparities in short-term outcomes after breast reduction surgery–A National Surgical Quality Improvement Project Analysis with 23,268 patients using Propensity Score Matching. Journal Of Plastic Reconstructive & Aesthetic Surgery 2022, 75: 1849-1857. PMID: 35131191, DOI: 10.1016/j.bjps.2022.01.001.Peer-Reviewed Original ResearchConceptsBreast reduction surgeryPropensity scoreSurgical complicationsPreoperative variablesReduction surgerySurgeons National Surgical Quality Improvement Program databaseNational Surgical Quality Improvement Program databaseQuality Improvement Program databaseMajor surgical complicationsImprovement Program databaseMinor surgical complicationsShort-term outcomesNon-white patientsNumber of patientsEthnic health inequalitiesNon-white cohortsPostoperative outcomesDiabetes mellitusMajor complicationsMedical complicationsSurgical outcomesPatient ethnicityProgram databaseInclusion criteriaSurgical care
2021
The Impact of Metabolic Syndrome on Microvascular Head and Neck Reconstruction: An ACS-NSQIP data analysis
Panayi AC, Haug V, Kauke-Navarro M, Diehm YF, Pomahac B. The Impact of Metabolic Syndrome on Microvascular Head and Neck Reconstruction: An ACS-NSQIP data analysis. Journal Of Plastic Reconstructive & Aesthetic Surgery 2021, 75: 1360-1371. PMID: 34955390, DOI: 10.1016/j.bjps.2021.11.074.Peer-Reviewed Original ResearchConceptsSuperficial incisional infectionSeptic shockMedical complicationsNeck microvascular reconstructionMetS patientsMicrovascular reconstructionIncisional infectionPostoperative outcomesMetS groupMetabolic syndromeSurgical outcomesHigh rateOrgan space infectionPostoperative medical complicationsOccurrence of sepsisAverage operative timeImpact of MetSMicrovascular flap reconstructionPoor surgical outcomesSkilled care facilitySite of surgeryFree skin flapsType of flapTerms of demographicsHospital stayThe modified 5-item frailty index is a predictor of perioperative risk in head and neck microvascular reconstruction: An analysis of 3795 cases
Panayi AC, Haug V, Kauke-Navarro M, Foroutanjazi S, Diehm YF, Pomahac B. The modified 5-item frailty index is a predictor of perioperative risk in head and neck microvascular reconstruction: An analysis of 3795 cases. American Journal Of Otolaryngology 2021, 42: 103121. PMID: 34171698, DOI: 10.1016/j.amjoto.2021.103121.Peer-Reviewed Original ResearchMeSH KeywordsAgedAnastomosis, SurgicalDiabetes MellitusFemaleForecastingFrailtyHeadHeart FailureHumansHypertensionLength of StayMaleMicrovesselsMiddle AgedNeckOperative TimePlastic Surgery ProceduresPostoperative ComplicationsPulmonary Disease, Chronic ObstructiveSeverity of Illness IndexSurgical FlapsTreatment OutcomeConceptsNeck microvascular reconstructionMFI-5Microvascular reconstructionMFI scoreSubgroup analysisNational Surgical Quality Improvement Program databaseQuality Improvement Program databaseChronic obstructive pulmonary diseaseFrailty index-5Non-home dischargeImprovement Program databaseAverage operative timeCongestive heart failureObstructive pulmonary diseasePost-operative outcomesPre-operative identificationPost-operative supportTerms of demographicsHospital stayPerioperative riskUnplanned readmissionHome dischargePostoperative outcomesYounger patientsFrailty index