2018
Applicability of the Curaçao Criteria for the Diagnosis of Hereditary Hemorrhagic Telangiectasia in the Pediatric Population
Pahl KS, Choudhury A, Wusik K, Hammill A, White A, Henderson K, Pollak J, Kasthuri RS. Applicability of the Curaçao Criteria for the Diagnosis of Hereditary Hemorrhagic Telangiectasia in the Pediatric Population. The Journal Of Pediatrics 2018, 197: 207-213. PMID: 29655863, DOI: 10.1016/j.jpeds.2018.01.079.Peer-Reviewed Original Research
2015
Hemorrhage Rates From Brain Arteriovenous Malformation in Patients With Hereditary Hemorrhagic Telangiectasia
Kim H, Nelson J, Krings T, terBrugge K, McCulloch C, Lawton M, Young W, Faughnan M, Chakinala M, Gossage J, Henderson K, Iyer V, Kasthuri R, Lin D, Mager J, McWilliams J, McDonald J, Pawlikowska L, Pollak J, Ratjen F, Swanson K, Vethanayagam D, White A, White R, Wilcox P. Hemorrhage Rates From Brain Arteriovenous Malformation in Patients With Hereditary Hemorrhagic Telangiectasia. Stroke 2015, 46: 1362-1364. PMID: 25858236, PMCID: PMC4415515, DOI: 10.1161/strokeaha.114.007367.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAneurysm, RupturedChildChild, PreschoolCohort StudiesFemaleHumansInfantInfant, NewbornIntracranial Arteriovenous MalformationsIntracranial HemorrhagesMaleMiddle AgedRecurrenceRetrospective StudiesSocioeconomic FactorsSurvival AnalysisTelangiectasia, Hereditary HemorrhagicYoung AdultConceptsHereditary hemorrhagic telangiectasiaBrain arteriovenous malformationsICH rateArteriovenous malformationsHemorrhage rateHemorrhagic telangiectasiaHigher ICH ratesIntracranial hemorrhage rateMajority of patientsICH presentationSymptomatic casesSystemic diseaseICH eventsMean ageAsymptomatic screeningMucocutaneous telangiectasiaHHT patientsHigh riskUnruptured casesPatientsMalformationsDiagnosisTelangiectasiaRehemorrhageEpistaxis
2012
Brain arteriovenous malformations associated with hereditary hemorrhagic telangiectasia: Gene–phenotype correlations
Nishida T, Faughnan ME, Krings T, Chakinala M, Gossage JR, Young WL, Kim H, Pourmohamad T, Henderson KJ, Schrum SD, James M, Quinnine N, Bharatha A, terBrugge KG, White RI. Brain arteriovenous malformations associated with hereditary hemorrhagic telangiectasia: Gene–phenotype correlations. American Journal Of Medical Genetics Part A 2012, 158A: 2829-2834. PMID: 22991266, PMCID: PMC3610331, DOI: 10.1002/ajmg.a.35622.Peer-Reviewed Original ResearchMeSH KeywordsActivin Receptors, Type IIAdolescentAdultAgedAntigens, CDArteriovenous FistulaChildChild, PreschoolEndoglinFemaleGenetic Association StudiesHumansInfantInfant, NewbornIntracellular Signaling Peptides and ProteinsIntracranial Arteriovenous MalformationsMaleMiddle AgedMutationReceptors, Cell SurfaceSmad4 ProteinTelangiectasia, Hereditary HemorrhagicYoung AdultConceptsBrain arteriovenous malformationsHereditary hemorrhagic telangiectasiaHistory of ICHIntracranial hemorrhageArteriovenous malformationsMean ageVascular malformationsHemorrhagic telangiectasiaMultiple brain arteriovenous malformationsAutosomal dominant genetic diseaseDominant genetic diseaseGenetic test resultsAVM characteristicsClinical manifestationsAVM diagnosisPatientsInitial examinationMultiple organsLarger studyACVRL1 mutationsENG mutationsMalformationsAgeSignificant differencesManifestations
2011
Reproducibility of Oxygen Saturation Monitoring During Six-Minute Walk Test and Exercise Stress Test in Patients with Pulmonary Arteriovenous Malformations Associated With Hereditary Hemorrhagic Telangiectasia
Li W, Niu B, Henderson K, Northrup V, Pollak JS, Trow T, Fahey J, White RI. Reproducibility of Oxygen Saturation Monitoring During Six-Minute Walk Test and Exercise Stress Test in Patients with Pulmonary Arteriovenous Malformations Associated With Hereditary Hemorrhagic Telangiectasia. Pediatric Cardiology 2011, 32: 590-594. PMID: 21336824, DOI: 10.1007/s00246-011-9917-8.Peer-Reviewed Original ResearchConceptsPulmonary arteriovenous malformationsHereditary hemorrhagic telangiectasiaOxygen saturationHeart rateWalk testArteriovenous malformationsHemorrhagic telangiectasiaSix-minute walk testOxygen saturation monitoringLowest oxygen saturationYears of ageHuman Investigation CommitteeStress testIntraclass correlation coefficientAnatomic subtypesExercise capacityMultiple complicationsPatientsAdjunct testSaturation monitoringAdequate restReproducible measureMalformationsTelangiectasiaBroad spectrum
2009
Results of Exercise Stress Testing in Patients with Diffuse Pulmonary Arteriovenous Malformations
Murphy J, Pierucci P, Chyun D, Henderson KJ, Pollak J, White RI, Fahey J. Results of Exercise Stress Testing in Patients with Diffuse Pulmonary Arteriovenous Malformations. Pediatric Cardiology 2009, 30: 978-984. PMID: 19636485, DOI: 10.1007/s00246-009-9491-5.Peer-Reviewed Original ResearchConceptsDiffuse pulmonary arteriovenous malformationsExercise stress testingPulmonary arteriovenous malformationsOxygen saturationMaximum exerciseArteriovenous malformationsRoom air oxygen saturationMean oxygen saturationStress testingCycle ergometer testNoncontrast chestBilateral involvementFrequent complicationComplete embolizationSerial studiesPatientsErgometer testOwn controlYoung adultsNoninvasive methodLimited experienceSignificant differencesMalformationsBaselineAge
2008
New Definition and Natural History of Patients With Diffuse Pulmonary Arteriovenous Malformations Twenty-Seven–Year Experience
Pierucci P, Murphy J, Henderson KJ, Chyun DA, White RI. New Definition and Natural History of Patients With Diffuse Pulmonary Arteriovenous Malformations Twenty-Seven–Year Experience. CHEST Journal 2008, 133: 653-661. PMID: 18198252, DOI: 10.1378/chest.07-1949.Peer-Reviewed Original ResearchConceptsDiffuse pulmonary arteriovenous malformationsPulmonary arteriovenous malformationsBilateral involvementArteriovenous malformationsOxygen saturationInitial oxygen saturationSegmental pulmonary arteriesHigh-risk groupOperative deathsLung transplantConsecutive patientsDuodenal ulcerPulmonary arterySignificant morbidityArtery originLiver necrosisFemale genderBrain hemorrhagePatientsMortality rateNatural historyYears' experienceHemoptysisHemorrhageDeath
2006
Clinical and Anatomic Outcomes after Embolotherapy of Pulmonary Arteriovenous Malformations
Pollak JS, Saluja S, Thabet A, Henderson KJ, Denbow N, White RI. Clinical and Anatomic Outcomes after Embolotherapy of Pulmonary Arteriovenous Malformations. Journal Of Vascular And Interventional Radiology 2006, 17: 35-45. PMID: 16415131, DOI: 10.1097/01.rvi.0000191410.13974.b6.Peer-Reviewed Original ResearchConceptsPulmonary AVMsResidual lesionsCollateral vesselsPulmonary arteriovenous malformation (PAVM) embolizationBronchial collateral vesselsPulmonary collateral vesselsOnset of symptomsPulmonary arteriovenous malformationsArteriovenous malformation embolizationHereditary hemorrhagic telangiectasiaHelical computed tomographyUnderwent embolizationAnatomic outcomesAsymptomatic eventsCerebral ischemiaRespiratory manifestationsAnatomic evaluationPhysiologic evaluationSymptomatic eventsArteriovenous malformationsAVM embolizationClinical assessmentHemorrhagic telangiectasiaComputed tomographyPatients
2004
Pulmonary arteriovenous malformations in children: Outcomes of transcatheter embolotherapy
Faughnan ME, Thabet A, Mei-Zahav M, Colombo M, MacLusky I, Hyland RH, Pugash RA, Chait P, Henderson KJ, White RI. Pulmonary arteriovenous malformations in children: Outcomes of transcatheter embolotherapy. The Journal Of Pediatrics 2004, 145: 826-831. PMID: 15580209, DOI: 10.1016/j.jpeds.2004.08.046.Peer-Reviewed Original ResearchConceptsPulmonary arteriovenous malformationsTranscatheter embolotherapyArteriovenous malformationsPleuritic chest painLife-threatening complicationsLong-term complicationsChest painNeurologic complicationsComplication rateMean ageComplicationsPatientsFurther complicationsEmbolotherapyAdult ratesChildrenMalformationsOutcomesHemoptysisCyanosisReperfusionPain
2000
Pulmonary arteriovenous malformations: cerebral ischemia and neurologic manifestations.
Moussouttas M, Fayad P, Rosenblatt M, Hashimoto M, Pollak J, Henderson K, Ma T, White R. Pulmonary arteriovenous malformations: cerebral ischemia and neurologic manifestations. Neurology 2000, 55: 959-64. PMID: 11061251, DOI: 10.1212/wnl.55.7.959.Peer-Reviewed Original ResearchConceptsMultiple pulmonary arteriovenous malformationsSingle pulmonary arteriovenous malformationPulmonary arteriovenous malformationsNeurologic manifestationsCortical infarctionParadoxical embolizationCerebral ischemiaRadiologic evidenceTreatment of PAVMsRetrospective cross-sectional studyCerebral imaging studiesNumber of PAVMsCross-sectional studyConsecutive patientsIschemic involvementPulmonary angiographyArtery diameterSubcortical infarctionAneurysmal sizeArteriovenous malformationsGreater oddsGreater prevalencePatientsInfarctionImaging studies