P436Role of myocardial proteostasis in hypoxic tolerance: effect of chemical chaperones and er stress inducers
Jain K, Ganju L, Suryakumar G. P436Role of myocardial proteostasis in hypoxic tolerance: effect of chemical chaperones and er stress inducers. Cardiovascular Research 2014, 103: s80-s80. DOI: 10.1093/cvr/cvu091.115.Peer-Reviewed Original ResearchChemical chaperonesProtein modificationER stressStress inducersHypoxic toleranceRole of proteinsOxidative protein modificationsER stress inducersHeat shock protein expressionStress toleranceProtein homeostasisInhibition of apoptosisProtein misfoldingShock protein expressionEnvironmental stressHarsh environmental conditionsExpression analysisER stress activationChaperonesUPR markersGreater protein oxidationER stress markersBiochemical assaysEnvironmental conditionsProtein oxidation