2024
Serial Mass Screening for Tuberculosis Among Incarcerated Persons in Brazil
de Araujo R, Martinez L, da Silva Santos A, Lemos E, de Oliveira R, Croda M, Silva D, Lemes I, Cunha E, Gonçalves T, dos Santos P, da Silva B, Gonçalves C, Andrews J, Croda J. Serial Mass Screening for Tuberculosis Among Incarcerated Persons in Brazil. Clinical Infectious Diseases 2024, 78: 1669-1676. PMID: 38324908, PMCID: PMC11175667, DOI: 10.1093/cid/ciae055.Peer-Reviewed Original ResearchScreening roundsIncarcerated personsMass screeningIndividual prisonersIncarcerated peoplePrison populationBrazilian prisonsCases of pulmonary tuberculosisHigh-risk populationPrisonHealth QuestionnaireChest X-rayImprove case detectionPrevalence of tuberculosisRate of tuberculosisTB screeningMedian scoreHyperendemic settingsPulmonary tuberculosisXpert MTB/RIFTB scoreTuberculosis casesTuberculosis burdenCase detectionTuberculosis
2023
Global, regional, and national estimates of tuberculosis incidence and case detection among incarcerated individuals from 2000 to 2019: a systematic analysis
Martinez L, Warren J, Harries A, Croda J, Espinal M, Olarte R, Avedillo P, Lienhardt C, Bhatia V, Liu Q, Chakaya J, Denholm J, Lin Y, Kawatsu L, Zhu L, Horsburgh C, Cohen T, Andrews J. Global, regional, and national estimates of tuberculosis incidence and case detection among incarcerated individuals from 2000 to 2019: a systematic analysis. The Lancet Public Health 2023, 8: e511-e519. PMID: 37393090, PMCID: PMC10323309, DOI: 10.1016/s2468-2667(23)00097-x.Peer-Reviewed Original ResearchConceptsTuberculosis incidenceCase detection ratioIncidence rateCase detectionHigh tuberculosis incidence ratesGlobal tuberculosis control effortsIncident tuberculosis casesTuberculosis incidence rateIncarcerated individualsTuberculosis control effortsTuberculosis case detectionTuberculosis casesNotification ratesNational incidenceTuberculosis notificationsGlobal incidenceHigh riskPrevalence estimatesNational estimatesWHO regionsIncidenceStudy periodMeta-regression frameworkTuberculosisNational InstituteScaling up evidence-based approaches to tuberculosis screening in prisons
Charalambous S, Velen K, Rueda Z, Croda J, Herce M, Shenoi S, Altice F, Muyoyeta M, Telisinghe L, Grandjean L, Keshavjee S, Andrews J. Scaling up evidence-based approaches to tuberculosis screening in prisons. The Lancet Public Health 2023, 8: e305-e310. PMID: 36780916, DOI: 10.1016/s2468-2667(23)00002-6.Commentaries, Editorials and LettersConceptsIncidence of tuberculosisCase-finding strategyHigh tuberculosis burdenMinistry of HealthEvidence-based approachTuberculosis burdenTreatment cascadeTuberculosis screeningTuberculosis notificationsTuberculosis diagnosisGeneral populationCare programDiagnostic strategiesTuberculosisEvidence baseSystematic screeningHigh rateIncidenceScreeningSettingSpread of Mycobacterium tuberculosis in Southern Brazilian persons deprived of liberty: a molecular epidemiology study
Busatto C, Possuelo L, Bierhals D, de Oliveira C, de Souza M, Fanfa D, Barreto É, Schwarzbold P, Von Groll A, Portugal I, Perdigão J, Croda J, Andrews J, da Silva P, Ramis I. Spread of Mycobacterium tuberculosis in Southern Brazilian persons deprived of liberty: a molecular epidemiology study. European Journal Of Clinical Microbiology & Infectious Diseases 2023, 42: 297-304. PMID: 36701032, DOI: 10.1007/s10096-023-04546-4.Peer-Reviewed Original ResearchConceptsAnti-TB drug resistanceM. tuberculosisTB control programsCross-sectional studyM. tuberculosis strainsMolecular epidemiology studiesTB burdenLAM strainsTuberculosis strainsEpidemiology studiesDrug resistanceMycobacterium tuberculosisCentral laboratoryTranslational researchTuberculosisCommon strainControl programsPDLMolecular characterizationHaarlemImproved strategiesPersonsPhylogeography and transmission of Mycobacterium tuberculosis spanning prisons and surrounding communities in Paraguay
Sanabria G, Sequera G, Aguirre S, Méndez J, dos Santos P, Gustafson N, Godoy M, Ortiz A, Cespedes C, Martínez G, García-Basteiro A, Andrews J, Croda J, Walter K. Phylogeography and transmission of Mycobacterium tuberculosis spanning prisons and surrounding communities in Paraguay. Nature Communications 2023, 14: 303. PMID: 36658111, PMCID: PMC9849832, DOI: 10.1038/s41467-023-35813-9.Peer-Reviewed Original ResearchConceptsIncident tuberculosis casesTB control programsTuberculosis casesRecent transmissionTransmission clustersNew infectionsProspective genomic surveillanceTransmission riskM. tuberculosisMycobacterium tuberculosisGenomic surveillanceMycobacterium tuberculosis complex genomeTuberculosisOutside prisonTransmission linkageControl programsInfectionIncidence
2022
Tuberculosis in prison inmates in Southern Brazil: investigating the epidemiological and operational indicators
Busatto C, Mespaque J, Schwarzbold P, de Souza C, Jarczewski C, Meucci R, Andrews J, Croda J, da Silva P, Ramis I, Possuelo L. Tuberculosis in prison inmates in Southern Brazil: investigating the epidemiological and operational indicators. Revista Da Sociedade Brasileira De Medicina Tropical 2022, 55: e0052-2022. PMID: 36287468, PMCID: PMC9592108, DOI: 10.1590/0037-8682-0052-2022.Peer-Reviewed Original ResearchConceptsPulmonary tuberculosis casesTuberculosis casesPulmonary tuberculosisLaboratory confirmationNew casesNew pulmonary tuberculosis casesRetreatment pulmonary tuberculosis casesWorldwide public health problemNotifiable Diseases Information SystemNew TB casesPublic health problemPublic health measuresTB casesHIV testingTuberculosis controlLaboratory criteriaTuberculosis incidenceIncidence rateObservational studyHealth problemsHealth measuresTuberculosisSpecific populationsHIVInvestigation rates
2020
Oral swab testing by Xpert® MTB/RIF Ultra for mass tuberculosis screening in prisons
Lima F, Santos A, Oliveira R, Silva C, Gonçalves C, Andrews J, Croda J. Oral swab testing by Xpert® MTB/RIF Ultra for mass tuberculosis screening in prisons. Journal Of Clinical Tuberculosis And Other Mycobacterial Diseases 2020, 19: 100148. PMID: 32099908, PMCID: PMC7031315, DOI: 10.1016/j.jctube.2020.100148.Peer-Reviewed Original ResearchNucleic acid amplification testsOral swabsPulmonary tuberculosisSwab testingAmplification testsMTB/RIF UltraMass screening studyOral swab samplingCourse of illnessScreening studySputum cultureXpert testingBacillary loadMycobacterial loadCase findingSputumXpertSwabsTuberculosisFurther studiesSwab samplingParticipantsComparable sensitivityPrison inmatesIndividualsCost-effectiveness of a Pharmacogenomic Test for Stratified Isoniazid Dosing in Treatment of Active Tuberculosis
Rens N, Groot C, Goldhaber-Fiebert J, Croda J, Andrews J. Cost-effectiveness of a Pharmacogenomic Test for Stratified Isoniazid Dosing in Treatment of Active Tuberculosis. Clinical Infectious Diseases 2020, 71: 3136-3143. PMID: 31905381, PMCID: PMC7819527, DOI: 10.1093/cid/ciz1212.Peer-Reviewed Original ResearchConceptsDrug-susceptible tuberculosisIncremental cost-effectiveness ratioSlow NAT2 acetylatorsWeight-based dosingOne-way sensitivity analysesCost-effectiveness ratioN-acetyltransferase 2 geneEffectiveness of drugsProbabilistic sensitivity analysesPotential clinical impactGeneXpert testActive tuberculosisNAT2 acetylatorsTreatment failurePharmacokinetic variabilityRapid acetylatorsTuberculosis treatmentClinical impactMAIN OUTCOMEPharmacogenomic testsHealth outcomesIsoniazid toxicityInterindividual variabilityPatientsTuberculosis
2019
A fieldable electrostatic air sampler enabling tuberculosis detection in bioaerosols
de Sousa N, Sandström N, Shen L, Håkansson K, Vezozzo R, Udekwu K, Croda J, Rothfuchs A. A fieldable electrostatic air sampler enabling tuberculosis detection in bioaerosols. Tuberculosis 2019, 120: 101896. PMID: 32090857, PMCID: PMC7049907, DOI: 10.1016/j.tube.2019.101896.Peer-Reviewed Original ResearchConceptsTB hotspotsM. tuberculosisActive pulmonary diseaseAirborne M. tuberculosisElectrostatic air samplerInhalation of aerosolsViable Mycobacterium tuberculosisPulmonary diseaseTB controlTB transmissionM. bovis BCGTuberculosisInfectious diseasesMycobacterium tuberculosisBovis BCGTuberculosis detectionMore human livesMolecular signaturesDiseaseCoughPatientsWorld populationInhalationBCGImportant roleGenetic Diversity and Molecular Epidemiology of Mycobacterium tuberculosis in Roraima State, Brazil.
Tatara M, Perdigão J, Viveiros M, Kritski A, Silva K, Sacchi F, de Lima C, Dos Santos P, Diniz J, Almeida Silva P, Gomes P, Gomes M, Cunha E, Lapa E Silva J, Portugal I, Croda J, Andrade M. Genetic Diversity and Molecular Epidemiology of Mycobacterium tuberculosis in Roraima State, Brazil. American Journal Of Tropical Medicine And Hygiene 2019, 101: 774-779. PMID: 31392954, PMCID: PMC6779181, DOI: 10.4269/ajtmh.19-0324.Peer-Reviewed Original ResearchConceptsPopulation-based prospective studyDrug resistanceMolecular epidemiologyResistance profilesRepetitive units-variable numberMTB/RIFDrug susceptibility testDrug resistance profilesTransmission of MtbPublic health policyPhenotypic resistance profilesIsoniazid monoTB preventionProspective studyNew strain typesTB epidemiologyPrimary resistanceHigh prevalenceMTB isolatesProportion methodHealth policyMycobacterium tuberculosisSusceptibility testsTuberculosisVulnerable populationsDetection, survival and infectious potential of Mycobacterium tuberculosis in the environment: a review of the evidence and epidemiological implications
Martinez L, Verma R, Croda J, Horsburgh C, Walter K, Degner N, Middelkoop K, Koch A, Hermans S, Warner D, Wood R, Cobelens F, Andrews J. Detection, survival and infectious potential of Mycobacterium tuberculosis in the environment: a review of the evidence and epidemiological implications. European Respiratory Journal 2019, 53: 1802302. PMID: 31048345, PMCID: PMC6753378, DOI: 10.1183/13993003.02302-2018.Peer-Reviewed Original ResearchConceptsInfectious tuberculosis patientsTuberculosis patientsTB transmissionCongregate settingsMouse modelGuinea pigsInfectious threatsMycobacterium tuberculosisDroplet nucleiConsistent findingScientific evidenceInfectious potentialEpidemiological implicationsPrimary routeFurther investigationSeminal experimental studiesRecent studiesHuman sourcesEvidencePatientsTuberculosisFindingsStudyInfectiousnessViabilityCorrection: Evaluating strategies for control of tuberculosis in prisons and prevention of spillover into communities: An observational and modeling study from Brazil
Mabud TS, de Lourdes Delgado Alves M, Ko AI, Basu S, Walter KS, Cohen T, Mathema B, Colijn C, Lemos E, Croda J, Andrews JR. Correction: Evaluating strategies for control of tuberculosis in prisons and prevention of spillover into communities: An observational and modeling study from Brazil. PLOS Medicine 2019, 16: e1002764. PMID: 30822314, PMCID: PMC6396896, DOI: 10.1371/journal.pmed.1002764.Peer-Reviewed Original ResearchControl of tuberculosisTuberculosis
2018
Building capacity for advances in tuberculosis research; proceedings of the third RePORT international meeting
van der Heijden Y, Abdullah F, Andrade B, Andrews J, Christopher D, Croda J, Ewing H, Haas D, Hatherill M, Horsburgh C, Mave V, Nakaya H, Rolla V, Srinivasan S, Sugiyono R, Ugarte-Gil C, Hamilton C. Building capacity for advances in tuberculosis research; proceedings of the third RePORT international meeting. Tuberculosis 2018, 113: 153-162. PMID: 30514497, PMCID: PMC6349374, DOI: 10.1016/j.tube.2018.09.009.Peer-Reviewed Original ResearchConceptsType 2 diabetes mellitusTuberculosis researchActive pulmonary tuberculosisHigh-risk populationEnrollment of participantsContext of HIVUnderstanding of tuberculosisHousehold contactsActive tuberculosisObservational cohortPulmonary tuberculosisDiabetes mellitusTuberculosis transmissionClinical dataIncipient tuberculosisNovel biomarkersTB participantsHost immunityStandardized research protocolsTuberculosisResearch capacity developmentHIVResearch protocolBiomarker identificationInternational meetingsThe role of the Brazilian Tuberculosis Research Network in national and international efforts to eliminate tuberculosis
Kritski A, Dalcolmo M, Mello F, Carvalho A, Silva D, Oliveira M, Croda J. The role of the Brazilian Tuberculosis Research Network in national and international efforts to eliminate tuberculosis. Jornal Brasileiro De Pneumologia 2018, 44: 77-81. PMID: 29791548, PMCID: PMC6044657, DOI: 10.1590/s1806-37562017000000435.Peer-Reviewed Original Research
2017
Genetic Clustering of Tuberculosis in an Indigenous Community of Brazil.
Correia Sacchi F, Tatara M, Camioli de Lima C, Ferreia da Silva L, Cunha E, Simonsen V, Ferrazoli L, Gomes H, Gonçalves Vasconcellos S, Suffys P, Andrews J, Croda J. Genetic Clustering of Tuberculosis in an Indigenous Community of Brazil. American Journal Of Tropical Medicine And Hygiene 2017, 98: 372-375. PMID: 29210353, PMCID: PMC5929193, DOI: 10.4269/ajtmh.17-0480.Peer-Reviewed Original ResearchCystic fibrosis carriership and tuberculosis: hints toward an evolutionary selective advantage based on data from the Brazilian territory
Bosch L, Bosch B, De Boeck K, Nawrot T, Meyts I, Vanneste D, Le Bourlegat C, Croda J, da Silva Filho L. Cystic fibrosis carriership and tuberculosis: hints toward an evolutionary selective advantage based on data from the Brazilian territory. BMC Infectious Diseases 2017, 17: 340. PMID: 28499359, PMCID: PMC5429554, DOI: 10.1186/s12879-017-2448-z.Peer-Reviewed Original ResearchConceptsCystic fibrosisCommon fatal genetic diseaseMellitus type 2Mycobacterium tuberculosis infectionAIDS incidence ratesTuberculosis infectionTB incidenceMtb infectionTuberculosis incidenceIncidence rateSmoking dataType 2Fatal genetic diseaseRelative protectionCF carriersConfoundersMonthly incomeInfectionIncidenceNegative correlationSpatial epidemiologyGenetic diseasesFibrosisEvolutionary selective advantageTuberculosis
2016
Epidemiological study of hepatitis B virus among prisoners with active tuberculosis in Central Brazil.
Iglecias L, Puga M, Pompílio M, Teles S, Croda J, Lima L, Lago B, Martins R, Motta-Castro A. Epidemiological study of hepatitis B virus among prisoners with active tuberculosis in Central Brazil. The International Journal Of Tuberculosis And Lung Disease 2016, 20: 1509-1515. PMID: 27776593, DOI: 10.5588/ijtld.15.0743.Peer-Reviewed Original ResearchConceptsHepatitis B virusActive tuberculosisHBV infectionB virusRisk factorsHBV surface antigen prevalenceImportant public health concernCo-infection prevalenceHBsAg-positive samplesCross-sectional studyInfection prevalence ratePublic health concernHBV DNASerological markersOverall prevalenceAntigen prevalencePrevalence ratesEffective treatmentEpidemiological studiesGenotype distributionMultivariate analysisPrison inmatesTuberculosisHealth concernInfectionSynthesis, in vitro Antiproliferative and Anti-Mycobacterium tuberculosis Activities of Novel β-Carboline Derivatives
Moreira F, Croda J, Sarragiotto M, Foglio M, Ruiz A, Carvalho J, Formagio A. Synthesis, in vitro Antiproliferative and Anti-Mycobacterium tuberculosis Activities of Novel β-Carboline Derivatives. Journal Of The Brazilian Chemical Society 2016, 27: 1398-1405. DOI: 10.5935/0103-5053.20160062.Peer-Reviewed Original ResearchM. tuberculosisNCI/ADRNCI/ADR cellsCell linesAnti-Mycobacterium tuberculosis activityCancer cell linesHuman cancer cell linesAnti-Mycobacterium tuberculosisΒ-carbolinesTumor cell linesGrowth inhibitory activityADR cellsTuberculosis activityOral bioavailabilityHuman tumor cell linesTerminal guanidine groupTuberculosisΒ-carboline derivativesInhibitory activityAntiproliferative activitySignificant activityGreater activityNovel β-carboline derivativesSilico studiesGroup
2015
Prisons as Reservoir for Community Transmission of Tuberculosis, Brazil - Volume 21, Number 3—March 2015 - Emerging Infectious Diseases journal - CDC
Sacchi FP, Praça RM, Tatara MB, Simonsen V, Ferrazoli L, Croda MG, Suffys PN, Ko AI, Andrews JR, Croda J. Prisons as Reservoir for Community Transmission of Tuberculosis, Brazil - Volume 21, Number 3—March 2015 - Emerging Infectious Diseases journal - CDC. Emerging Infectious Diseases 2015, 21: 452-455. PMID: 25642998, PMCID: PMC4344267, DOI: 10.3201/eid2103.140896.Peer-Reviewed Original Research
2013
Impact of Latent Infection Treatment in Indigenous Populations
Yuhara L, Sacchi F, Croda J. Impact of Latent Infection Treatment in Indigenous Populations. PLOS ONE 2013, 8: e71201. PMID: 23936264, PMCID: PMC3729554, DOI: 10.1371/journal.pone.0071201.Peer-Reviewed Original ResearchConceptsSmear-positive index casesTuberculin skin testActive tuberculosisLatent infectionIndex caseInfection treatmentLatent tuberculosisActive diseaseTuberculosis contactsRetrospective studySkin testClinical recordsRisk factorsNotification databaseMultidisciplinary teamClose contactTuberculosisInfectionTreatmentAgeEstimated numberPresent studyMorbidityIndigenous BraziliansCases