Synthesis, in vitro Antiproliferative and Anti-Mycobacterium tuberculosis Activities of Novel β-Carboline Derivatives
Moreira F, Croda J, Sarragiotto M, Foglio M, Ruiz A, Carvalho J, Formagio A. Synthesis, in vitro Antiproliferative and Anti-Mycobacterium tuberculosis Activities of Novel β-Carboline Derivatives. Journal Of The Brazilian Chemical Society 2016, 27: 1398-1405. DOI: 10.5935/0103-5053.20160062.Peer-Reviewed Original ResearchM. tuberculosisNCI/ADRNCI/ADR cellsCell linesAnti-Mycobacterium tuberculosis activityCancer cell linesHuman cancer cell linesAnti-Mycobacterium tuberculosisΒ-carbolinesTumor cell linesGrowth inhibitory activityADR cellsTuberculosis activityOral bioavailabilityHuman tumor cell linesTerminal guanidine groupTuberculosisΒ-carboline derivativesInhibitory activityAntiproliferative activitySignificant activityGreater activityNovel β-carboline derivativesSilico studiesGroup