2022
The effect of incarceration on TB treatment outcomes
O Marr J, Gonçalves C, Arakaki-Sanchez D, Pelissari D, Costa F, Croda J, Walter K, Andrews J. The effect of incarceration on TB treatment outcomes. The International Journal Of Tuberculosis And Lung Disease 2022, 26: 252-258. PMID: 35197165, DOI: 10.5588/ijtld.21.0449.Peer-Reviewed Original ResearchConceptsNon-incarcerated individualsTreatment successTreatment outcomesDrug-susceptible TB casesImproved treatment successTB treatment outcomesTB treatment successClinical risk factorsIncarcerated individualsMultivariate logistic regressionGreater treatment successTB casesClinical factorsObserved therapyPoor outcomeTB notificationsRisk factorsElevated riskGreater efficacyLogistic regressionNotifiable diseaseOutcomesIncarcerated populationsVulnerable individualsUse of DOT
2020
Primary Prophylaxis to Prevent Tuberculosis Infection in Prison Inmates: A Randomized, Double-Blind, Placebo-Controlled Trial.
Dias de Oliveira R, da Silva Santos A, Reis C, de Cássia Leite A, Correia Sacchi F, de Araujo R, Dos Santos P, Rolla V, Martinez L, Andrews J, Croda J. Primary Prophylaxis to Prevent Tuberculosis Infection in Prison Inmates: A Randomized, Double-Blind, Placebo-Controlled Trial. American Journal Of Tropical Medicine And Hygiene 2020, 103: 1466-1472. PMID: 32876010, PMCID: PMC7543866, DOI: 10.4269/ajtmh.20-0110.Peer-Reviewed Original ResearchConceptsQFT conversionTB infectionSecondary outcomesPlacebo-controlled trialQuantiFERON-TB GoldFuture clinical trialsPrimary prophylaxisMiddle-income countriesPrimary outcomeTuberculosis infectionIntervention armTuberculosis incidenceControl armTrial protocolClinical trialsElevated riskInterim analysisLatent infectionCutoff pointInfectionTrialsHigher cutoffSustained conversionInternational unitsLower rates