2022
Association between primary or booster COVID-19 mRNA vaccination and Omicron lineage BA.1 SARS-CoV-2 infection in people with a prior SARS-CoV-2 infection: A test-negative case–control analysis
Lind M, Robertson A, Silva J, Warner F, Coppi A, Price N, Duckwall C, Sosensky P, Di Giuseppe E, Borg R, Fofana M, Ranzani O, Dean N, Andrews J, Croda J, Iwasaki A, Cummings D, Ko A, Hitchings M, Schulz W. Association between primary or booster COVID-19 mRNA vaccination and Omicron lineage BA.1 SARS-CoV-2 infection in people with a prior SARS-CoV-2 infection: A test-negative case–control analysis. PLOS Medicine 2022, 19: e1004136. PMID: 36454733, PMCID: PMC9714718, DOI: 10.1371/journal.pmed.1004136.Peer-Reviewed Original ResearchConceptsSARS-CoV-2 infectionBooster vaccinationPrior infectionOmicron infectionPrimary vaccinationMRNA vaccinationOdds ratioAcute respiratory syndrome coronavirus 2 infectionSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infectionPrior SARS-CoV-2 infectionTest-negative case-control analysisYale New Haven Health SystemTest-negative case-control studyCOVID-19 mRNA vaccinationSyndrome coronavirus 2 infectionOmicron variant infectionPrior infection statusCoronavirus 2 infectionCase-control studyCase-control analysisOdds of infectionRisk of infectionRace/ethnicityBooster dosesDate of testEffectiveness of an inactivated Covid-19 vaccine with homologous and heterologous boosters against Omicron in Brazil
Ranzani OT, Hitchings MDT, de Melo RL, de França GVA, Fernandes CFR, Lind ML, Torres MSS, Tsuha DH, David LCS, Said RFC, Almiron M, de Oliveira RD, Cummings DAT, Dean NE, Andrews JR, Ko AI, Croda J. Effectiveness of an inactivated Covid-19 vaccine with homologous and heterologous boosters against Omicron in Brazil. Nature Communications 2022, 13: 5536. PMID: 36202800, PMCID: PMC9537178, DOI: 10.1038/s41467-022-33169-0.Peer-Reviewed Original Research
2021
Blood-based host biomarker diagnostics in active case finding for pulmonary tuberculosis: A diagnostic case-control study
Moreira F, Verma R, dos Santos P, Leite A, da Silva Santos A, de Araujo R, da Silva B, de Sá Queiroz J, Persing D, Södersten E, Gnanashanmugam D, Khatri P, Croda J, Andrews J. Blood-based host biomarker diagnostics in active case finding for pulmonary tuberculosis: A diagnostic case-control study. EClinicalMedicine 2021, 33: 100776. PMID: 33842866, PMCID: PMC8020164, DOI: 10.1016/j.eclinm.2021.100776.Peer-Reviewed Original ResearchCare C-reactive proteinXpert MTB/RIFMTB/RIFDiagnostic case-control studyXpert MTBCase-control studyTuberculosis casesTriage testSputum Xpert MTB/RIFHigh tuberculosis burden settingsActive casesSputum bacillary burdenC-reactive proteinHigh-burden populationsCulture-confirmed casesMass screening programCulture-negative controlsBacillary burdenTuberculosis symptomsPulmonary tuberculosisSputum cultureScreening program
2020
Risk factors for polymyxin-resistant carbapenemase-producing Enterobacteriaceae in critically ill patients: An epidemiological and clinical study
da Silva K, Baker S, Croda J, Nguyen T, Boinett C, Barbosa L, Tetila A, Simionatto S. Risk factors for polymyxin-resistant carbapenemase-producing Enterobacteriaceae in critically ill patients: An epidemiological and clinical study. International Journal Of Antimicrobial Agents 2020, 55: 105882. PMID: 31923570, DOI: 10.1016/j.ijantimicag.2020.105882.Peer-Reviewed Original ResearchConceptsRisk factorsPolymyxin-resistant strainsNeonatal patientsMortality rateNeonatal intensive care unitEnterobacteriaceae strainsOnly risk factorCentral venous cathetersIntensive care unitCase-control studyPotential risk factorsHigh mortality ratePolymyxin-susceptible strainsCarbapenemase-producing EnterobacteriaceaeCarbapenem exposureAdult patientsAminoglycoside useCarbapenem useRenal failureVenous cathetersIll patientsCare unitUnfavourable outcomePolymerase chain reactionUrinary catheterNeurosyphilis in Brazilian newborns: a health problem that could be avoided
da Costa Ribeiro A, de Sá Dan C, da Silva Santos A, Croda J, Simionatto S. Neurosyphilis in Brazilian newborns: a health problem that could be avoided. Revista Do Instituto De Medicina Tropical De São Paulo 2020, 62: e82. PMID: 33174978, PMCID: PMC7653815, DOI: 10.1590/s1678-9946202062082.Peer-Reviewed Original ResearchConceptsPregnant womenCongenital syphilisBrazilian newbornsHealth problemsLong bone radiographyPregnant Brazilian womenCerebrospinal fluid analysisLength of hospitalizationLow birth weightCase-control studyNon-treponemal testsCases of newbornsCases of neurosyphilisPublic health problemCentral nervous systemRisk of transmissionNeurosyphilis treatmentClinical complicationsPrenatal careBirth weightBone radiographyLate diagnosisPrenatal coverageNeurosyphilisNervous system
2018
A high mortality rate associated with multidrug-resistant Acinetobacter baumannii ST79 and ST25 carrying OXA-23 in a Brazilian intensive care unit
da Silva K, Maciel W, Croda J, Cayô R, Ramos A, de Sales R, Kurihara M, Vasconcelos N, Gales A, Simionatto S. A high mortality rate associated with multidrug-resistant Acinetobacter baumannii ST79 and ST25 carrying OXA-23 in a Brazilian intensive care unit. PLOS ONE 2018, 13: e0209367. PMID: 30592758, PMCID: PMC6310363, DOI: 10.1371/journal.pone.0209367.Peer-Reviewed Original ResearchMeSH KeywordsAcinetobacter baumanniiAcinetobacter InfectionsAdultAgedAged, 80 and overAnti-Bacterial AgentsBacterial ProteinsBeta-LactamasesBrazilCase-Control StudiesCross InfectionDrug Resistance, Multiple, BacterialFemaleHospital MortalityHumansIntensive Care UnitsMaleMicrobial Sensitivity TestsMiddle AgedConceptsOXA-23-producing A. baumanniiHigh mortality rateA. baumanniiMortality rateRisk factorsHealthcare-related risk factorsBrazilian intensive care unitsIntensive care unit patientsIntensive care unit settingCarbapenem-resistant Acinetobacter baumanniiISAba1 insertion sequenceA. baumannii infectionsCare unit patientsIntensive care unitBlaOXA-51 geneUse of cephalosporinsCase-control studyBaumannii infectionsUnit patientsCare unitNasogastric tubeTherapeutic optionsUnit settingNosocomial infectionsSuch infectionsAssessment of Validity of a Blood-Based 3-Gene Signature Score for Progression and Diagnosis of Tuberculosis, Disease Severity, and Treatment Response
Warsinske H, Rao A, Moreira F, Santos P, Liu A, Scott M, Malherbe S, Ronacher K, Walzl G, Winter J, Sweeney T, Croda J, Andrews J, Khatri P. Assessment of Validity of a Blood-Based 3-Gene Signature Score for Progression and Diagnosis of Tuberculosis, Disease Severity, and Treatment Response. JAMA Network Open 2018, 1: e183779. PMID: 30646264, PMCID: PMC6324428, DOI: 10.1001/jamanetworkopen.2018.3779.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAntitubercular AgentsBrazilChildCohort StudiesDisease ProgressionFemaleGenes, BacterialGenetic MarkersHumansLatent TuberculosisMaleMiddle AgedMolecular TypingMycobacterium tuberculosisReal-Time Polymerase Chain ReactionReproducibility of ResultsRNA, BacterialSeverity of Illness IndexTuberculosisYoung AdultConceptsTB scoreAdolescent cohort studyNegative predictive valueTreatment responseTB diseaseCohort studyTuberculosis infectionTriage testPositron emission tomography-computed tomography scanPredictive valueLatent M tuberculosis infectionLatent Mycobacterium tuberculosis infectionPrimary health care clinicsHigh negative predictive valueCulture-positive adultsM tuberculosis infectionWhole bloodMycobacterium tuberculosis infectionEnd of treatmentHealth care clinicsCase-control studyIndependent prospective cohortsDiagnosis of tuberculosisSlower treatment responseCase-control cohortSerum vitamin D levels and risk of prevalent tuberculosis, incident tuberculosis and tuberculin skin test conversion among prisoners
Maceda EB, Gonçalves C, Andrews JR, Ko AI, Yeckel CW, Croda J. Serum vitamin D levels and risk of prevalent tuberculosis, incident tuberculosis and tuberculin skin test conversion among prisoners. Scientific Reports 2018, 8: 997. PMID: 29343733, PMCID: PMC5772514, DOI: 10.1038/s41598-018-19589-3.Peer-Reviewed Original ResearchConceptsVitamin D levelsTuberculin skin test conversionPoor vitamin D statusSkin test conversionVitamin D statusActive tuberculosisRisk of progressionCase-control studyD levelsRisk factorsTST conversionD statusCigarette smokingTest conversionSerum vitamin D levelsSubnormal vitamin D levelsMultivariable conditional logistic regressionConditional logistic regressionConsequence of diseaseIncident tuberculosisActive diseaseLatent tuberculosisPrevalent tuberculosisVitamin DBlack race
2013
Sugar cane manufacturing is associated with tuberculosis in an indigenous population in Brazil
Sacchi FP, Croda MG, Estevan AO, Ko AI, Croda J. Sugar cane manufacturing is associated with tuberculosis in an indigenous population in Brazil. Transactions Of The Royal Society Of Tropical Medicine And Hygiene 2013, 107: 152-157. PMID: 23306443, DOI: 10.1093/trstmh/trs089.Peer-Reviewed Original ResearchConceptsCause of morbidityCase-control studySpecific epidemiological conditionsTB contactTB infectionTuberculosis infectionAnnual incidenceTuberculosis casesMale genderRisk factorsDisease surveillance programsMultivariate analysisTuberculosisDisease controlSurveillance programControl casesIndigenous populationsEpidemiological conditionsInfectionPotential relationshipPopulationNational disease surveillance programmeMorbidityMortalityIncidence