Blood-based host biomarker diagnostics in active case finding for pulmonary tuberculosis: A diagnostic case-control study
Moreira F, Verma R, dos Santos P, Leite A, da Silva Santos A, de Araujo R, da Silva B, de Sá Queiroz J, Persing D, Södersten E, Gnanashanmugam D, Khatri P, Croda J, Andrews J. Blood-based host biomarker diagnostics in active case finding for pulmonary tuberculosis: A diagnostic case-control study. EClinicalMedicine 2021, 33: 100776. PMID: 33842866, PMCID: PMC8020164, DOI: 10.1016/j.eclinm.2021.100776.Peer-Reviewed Original ResearchCare C-reactive proteinXpert MTB/RIFMTB/RIFDiagnostic case-control studyXpert MTBCase-control studyTuberculosis casesTriage testSputum Xpert MTB/RIFHigh tuberculosis burden settingsActive casesSputum bacillary burdenC-reactive proteinHigh-burden populationsCulture-confirmed casesMass screening programCulture-negative controlsBacillary burdenTuberculosis symptomsPulmonary tuberculosisSputum cultureScreening program