2019
Somatic PRKAR1A mutation in sporadic atrial myxoma with cerebral parenchymal metastases: a case report
Roque A, Kimbrough T, Traner C, Baehring JM, Huttner A, Adams J, Canosa S, Sklar J, Madri JA. Somatic PRKAR1A mutation in sporadic atrial myxoma with cerebral parenchymal metastases: a case report. Journal Of Medical Case Reports 2019, 13: 389. PMID: 31874650, PMCID: PMC6930684, DOI: 10.1186/s13256-019-2317-z.Peer-Reviewed Original ResearchMeSH KeywordsBrain NeoplasmsCarney ComplexChemoradiotherapyCyclic AMP-Dependent Protein Kinase RIalpha SubunitDopamine AgentsExome SequencingFemaleGene Expression Regulation, NeoplasticGenes, Tumor SuppressorGerm-Line MutationHeart NeoplasmsHumansIntracranial HemorrhagesMemantineMiddle AgedMyxomaTreatment OutcomeConceptsAtrial myxomaSporadic tumorsExtra-cardiac complicationsMetastatic cardiac myxomaMajority of tumorsDissemination of tumorsIntracranial hemorrhagic lesionsWhole-exome sequencingAutosomal dominant conditionConclusionsOur patientsSporadic myxomasInvasive tumor cellsParenchymal metastasesCardiac myxomaCase reportClinical behaviorHemorrhagic lesionsAneurysm formationBenign neoplasmsMyxomaSporadic lesionsVascular wallCarney complexTumorsGermline mutations
1993
Differential induction of VCAM-1 on human iliac venous and arterial endothelial cells and its role in adhesion.
Hauser I, Johnson D, Madri J. Differential induction of VCAM-1 on human iliac venous and arterial endothelial cells and its role in adhesion. The Journal Of Immunology 1993, 151: 5172-85. PMID: 7693806, DOI: 10.4049/jimmunol.151.10.5172.Peer-Reviewed Original ResearchMeSH KeywordsAdultCell AdhesionCell Adhesion MoleculesCells, CulturedE-SelectinEndothelium, VascularFemaleHumansIliac ArteryIliac VeinIntercellular Adhesion Molecule-1Lymphocyte Function-Associated Antigen-1Middle AgedReceptors, Very Late AntigenRNA, MessengerTetradecanoylphorbol AcetateTumor Necrosis Factor-alphaVascular Cell Adhesion Molecule-1ConceptsArterial endothelial cellsICAM-1VCAM-1Venous endothelial cellsEndothelial cellsTNF-alphaU937 cell adhesionELAM-1VCAM-1 cell surface expressionTNF-alpha-induced VCAM-1 expressionAdhesion molecules VCAM-1ICAM-2U937 cellsAdhesion molecules ICAM-1TNF-alpha-induced expressionLate activation AgVCAM-1 expressionMolecules ICAM-1VCAM-1/VLAMonocyte-like cell line U937TNF-alpha treatmentVessel endothelial cellsAdhesion of PMALarge vessel endothelial cellsEC types
1984
Bronchial Lavage Proteins as Correlates of Histopathologic Airway Changes in Healthy Smokers and Patients with Pulmonary Carcinoma1–4
Merrill W, Barwick K, Madri J, Strober W, Matthay R, Olchowski J, Naegel G, Reynolds H. Bronchial Lavage Proteins as Correlates of Histopathologic Airway Changes in Healthy Smokers and Patients with Pulmonary Carcinoma1–4. American Journal Of Respiratory And Critical Care Medicine 1984, 130: 905-9. PMID: 6208835, DOI: 10.1164/arrd.1984.130.5.905.Peer-Reviewed Original ResearchConceptsFree secretory componentSymptomatic smokersCarcinoma patientsAsymptomatic smokersLavage fluidLung diseaseCancer patientsSmoking-associated lung diseasePacks/yearHigh-risk subgroupsImportant etiologic factorNumber of smokersAirway changesAirway injuryGroups of subjectsHealthy smokersSmoking historyNormal nonsmokersLavage levelsCigarette smokingSmoking populationEtiologic factorsLavage proteinImmunohistochemical evidenceLung sections
1982
An immunohistochemical study of adenomatoid tumors utilizing keratin and factor VIII antibodies. Evidence for a mesothelial origin.
Barwick K, Madri J. An immunohistochemical study of adenomatoid tumors utilizing keratin and factor VIII antibodies. Evidence for a mesothelial origin. Laboratory Investigation 1982, 47: 276-80. PMID: 6180248.Peer-Reviewed Original ResearchConceptsAdenomatoid tumorMesothelial originAntigen antibodiesKeratin antibodiesFactor VIII antibodiesImmunohistochemical studyAdenoid cellsVIII antibodiesAdenoid structuresEndothelial originFactor VIIIParaffin blocksTumorsCases tissueAntibodiesHistochemical dataAntibody probesImmunoelectron microscopyAdditional evidenceCellsAntigenKeratin
1980
Collagen polymorphism in the lung An immunochemical study of pulmonary fibrosis
Madri J, Furthmayr H. Collagen polymorphism in the lung An immunochemical study of pulmonary fibrosis. Human Pathology 1980, 11: 353-366. PMID: 6997183, DOI: 10.1016/s0046-8177(80)80031-1.Peer-Reviewed Original ResearchConceptsPerivascular localizationLung samplesFibrotic human lungSmooth muscle cell proliferationType IIndirect immunofluorescence techniqueLung type IMuscle cell proliferationType VType IIICapillary basement membranePulmonary fibrosisFibrotic processAlveolar septaType IV collagenImmunofluorescence techniqueHuman lungCell proliferationInterstitiumMarked increaseType IVBasement membraneImmunochemical studiesIrregular localizationIV collagen
1978
Amyloid deposition in immunoblastic lymphadenopathy
Madri J, Fromowitz F. Amyloid deposition in immunoblastic lymphadenopathy. Human Pathology 1978, 9: 157-162. PMID: 640641, DOI: 10.1016/s0046-8177(78)80106-3.Peer-Reviewed Original Research