1993
Functional CD4 T cell subset interplay in an intact immune system.
Murray J, Madri J, Pasqualini T, Bottomly K. Functional CD4 T cell subset interplay in an intact immune system. The Journal Of Immunology 1993, 150: 4270-6. PMID: 8097751, DOI: 10.4049/jimmunol.150.10.4270.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCD4-Positive T-LymphocytesCollagenHistocompatibility Antigens Class IIInterferon-gammaLymphocyte ActivationMiceMice, Inbred StrainsT-Lymphocyte SubsetsT-Lymphocytes, Helper-InducerConceptsCD4 T cellsTh-2 cellsT cellsIL-5Antibody formationIFN-gammaTh-2-like cellsF1 hybrid T cellsIntact immune systemTh-1 cellsGood proliferative responsesCollagen IVCell primingProliferative responseImmune systemTh-1Hybrid miceMiceGamma treatmentAdditional studiesHuman collagen IVImmunizationSelective activationVivoCells
1992
Major histocompatibility complex (MHC) control of CD4 T cell subset activation. II. A single peptide induces either humoral or cell‐mediated responses in mice of distinct MHC genotype
Murray J, Pfeiffer C, Madri J, Bottomly K. Major histocompatibility complex (MHC) control of CD4 T cell subset activation. II. A single peptide induces either humoral or cell‐mediated responses in mice of distinct MHC genotype. European Journal Of Immunology 1992, 22: 559-565. PMID: 1347015, DOI: 10.1002/eji.1830220239.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAnimalsAntibody FormationAntigen-Presenting CellsCD4-Positive T-LymphocytesCollagenGenes, MHC Class IIHaptensHumansImmunity, CellularImmunologic MemoryLymph NodesLymphocyte ActivationLymphocyte CooperationMajor Histocompatibility ComplexMiceMolecular Sequence DataPeptidesT-Lymphocytes, Helper-Inducer
1991
Selective Activation of Th1‐ and Th2‐like Cells in vivo– Response to Human Collagen IV
Pfeiffer C, Murray J, Madri J, Bottomly K. Selective Activation of Th1‐ and Th2‐like Cells in vivo– Response to Human Collagen IV. Immunological Reviews 1991, 123: 65-84. PMID: 1684784, DOI: 10.1111/j.1600-065x.1991.tb00606.x.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCD4-Positive T-LymphocytesClone CellsCollagenGenotypeHumansImmunodominant EpitopesLymphocyte ActivationMajor Histocompatibility ComplexT-Lymphocytes, Helper-InducerConceptsT cell proliferative responsesTh2 responsesProliferative responseTh2 cellsT cellsT cell IL-4Collagen IVClass of immunityMHC class II moleculesT cell responsesActivation of Th1IFN-gamma releaseClass II MHC moleculesIL-5 releaseTypes of CD4Th2-like cellsClass II genotypesClass II moleculesMHC class II genotypeII MHC moleculesType of responseT cell ligandsMHC genotypeTh1 responseGamma release