2010
Angiogenesis, the Neurovascular Niche and Neuronal Reintegration After Injury
Lavik E, Madri J. Angiogenesis, the Neurovascular Niche and Neuronal Reintegration After Injury. 2010, 145-167. DOI: 10.1007/978-90-481-9495-7_7.Peer-Reviewed Original ResearchCell-matrix interactionsCentral nervous systemNeurogenic zonesCell biologyClinical improvementAffected individualsExtracellular matrixStem cellsCell proliferationNeuro-genesisNervous systemNeurodegenerative diseasesRepair processNicheTissue cultureSpinal cord injuryNeurovascular nicheComplete understandingDisease states
2009
Proteomic-Based Detection of a Protein Cluster Dysregulated during Cardiovascular Development Identifies Biomarkers of Congenital Heart Defects
Nath AK, Krauthammer M, Li P, Davidov E, Butler LC, Copel J, Katajamaa M, Oresic M, Buhimschi I, Buhimschi C, Snyder M, Madri JA. Proteomic-Based Detection of a Protein Cluster Dysregulated during Cardiovascular Development Identifies Biomarkers of Congenital Heart Defects. PLOS ONE 2009, 4: e4221. PMID: 19156209, PMCID: PMC2626248, DOI: 10.1371/journal.pone.0004221.Peer-Reviewed Original ResearchConceptsCardiovascular developmentMass spectrometry-based proteomicsSpectrometry-based proteomicsNormal cardiovascular developmentAdhesion/migrationHuman CHDsProteomic datasetsHeart developmentProtein clustersMurine embryosProtein pathwayMolecular pathwaysFunctional roleProteinEmbryonic survivalYolk sacProtein levelsIdentifies biomarkersCardiovascular defectsWestern blottingPathwayNovel avenuesEmbryosComplete understandingProtein biomarkers