2002
p53 Mutations as Tumor Markers in Fine Needle Aspirates of Palpable Breast Masses
Dillon DA, Hipolito E, Zheng K, Rimm DL, Costa JC. p53 Mutations as Tumor Markers in Fine Needle Aspirates of Palpable Breast Masses. Acta Cytologica 2002, 46: 841-847. PMID: 12365217, DOI: 10.1159/000327057.Peer-Reviewed Original ResearchMeSH KeywordsAbscessAdenocarcinomaAdultAgedAged, 80 and overAmino Acid SubstitutionBiomarkers, TumorBiopsy, NeedleBreast NeoplasmsCarcinoma, Ductal, BreastCodon, TerminatorCystsDNA Mutational AnalysisDNA, NeoplasmExonsFemaleFrameshift MutationGenes, p53GenotypeHumansMiddle AgedMutationPolymorphism, Single-Stranded ConformationalRetrospective StudiesConceptsFine needle aspiratesP53 exons 5Breast massesPolymerase chain reactionNeedle aspiratesP53 mutationsSingle-strand conformational polymorphism analysisSubsequent excisional biopsyPalpable breast massesPotential diagnostic utilityDefinitive cytologic diagnosisTumor cell markersExon 5Molecular diagnostic markersExcisional biopsyBenign cytologyBreast carcinomaSuspicious cytologyRetrospective analysisCytologic diagnosisTumor markersDiagnostic criteriaBiopsy tissueMorphologic diagnosisDiagnostic utility
1998
The Molecular Biology of Breast Cancer: Accelerating Clinical Applications
Dillon D, Howe C, Bosari S, Costa J. The Molecular Biology of Breast Cancer: Accelerating Clinical Applications. Critical Reviews™ In Oncogenesis 1998, 9: 125-140. PMID: 9973246, DOI: 10.1615/critrevoncog.v9.i2.30.Peer-Reviewed Original ResearchConceptsBreast cancerClinical applicationPreclinical disease modelsRegional oncology networkMolecular eventsOncology NetworkPractice guidelinesBRCA-1BRCA-2CancerGrowth factorTranslational researchDisease modelsPathogenesisCell deathBasic scienceCell cycle controlMetastasisClinicTherapyCycle controlMolecular biologyAbnormalitiesDiagnosis
1985
A randomized, prospective trial of adjuvant chemotherapy in adults with soft tissue sarcomas of the head and neck, breast, and trunk
Glenn J, Kinsella T, Glatstein E, Tepper J, Baker A, Sugarbaker P, Sindelar W, Roth J, Brennan M, Costa J, Seipp C, Wesley R, Young R, Rosenberg S. A randomized, prospective trial of adjuvant chemotherapy in adults with soft tissue sarcomas of the head and neck, breast, and trunk. Cancer 1985, 55: 1206-1214. PMID: 3882217, DOI: 10.1002/1097-0142(19850315)55:6<1206::aid-cncr2820550612>3.0.co;2-e.Peer-Reviewed Original ResearchConceptsDisease-free survivalActuarial disease-free survivalOverall actuarial survivalChemotherapy armAdjuvant chemotherapyOverall survivalActuarial survivalApparent congestive heart failureAggressive local treatmentUse of chemotherapyCongestive heart failureSubgroup of patientsHigh-grade sarcomaSoft tissue sarcomasPostoperative radiotherapyProspective trialComplete resectionHeart failureAdditional patientsTreatment armsGross tumorProspective studyTissue sarcomasLocal treatmentChemotherapy
1982
Histopathological features of rapidly progressing breast carcinoma in Tunisia: A study of 94 cases
Costa J, Webber B, Levine P, Muenz L, O'Conor G, Tabbane F, Belhassen S, Kamaraju L, Mourali N. Histopathological features of rapidly progressing breast carcinoma in Tunisia: A study of 94 cases. International Journal Of Cancer 1982, 30: 35-37. PMID: 6288578, DOI: 10.1002/ijc.2910300107.Peer-Reviewed Original ResearchConceptsHistological featuresCutaneous inflammatory infiltrateNuclear grade 3Breast carcinoma patientsCases of carcinomaPercentage of casesNumber of mitosesInflammatory carcinomaCarcinoma patientsHistopathological featuresInflammatory infiltrateTumor emboliNuclear gradeRapid progressionBreast carcinomaGrade 3Clinical classificationTumor typesBreast tissueCarcinomaPatientsCutaneous permeationBreastDermisPresent study
1981
Risk of subsequent contralateral breast carcinoma in a population of patients with in‐situ breast carcinoma
Webber B, Heise H, Neifeld J, Costa J. Risk of subsequent contralateral breast carcinoma in a population of patients with in‐situ breast carcinoma. Cancer 1981, 47: 2928-2932. PMID: 6266644, DOI: 10.1002/1097-0142(19810615)47:12<2928::aid-cncr2820471232>3.0.co;2-5.Peer-Reviewed Original ResearchConceptsBreast carcinomaContralateral carcinomaSubsequent cancerContralateral breast carcinomaMajority of patientsPopulation of patientsSecond breast cancerNoninvasive breast carcinomaSitu breast carcinomaContralateral tumorsOverall survivalContralateral breastHistological typeSurvival figuresLobular carcinomaOpposite breastBreast cancerSitu carcinomaCarcinomaS. womenCancerPatientsBreastWomenMastectomy