1993
Prognostic significance of K-ras mutations in colorectal carcinoma
Benhattar J, Losi L, Chaubert P, Givel J, Costa J. Prognostic significance of K-ras mutations in colorectal carcinoma. Gastroenterology 1993, 104: 1044-1048. PMID: 8462792, DOI: 10.1016/0016-5085(93)90272-e.Peer-Reviewed Original ResearchConceptsK-ras mutationsPrognostic significanceColorectal carcinomaK-ras geneRecurrent diseaseCodon 12Good prognostic factorAdvanced colorectal carcinomaPossible prognostic significanceHuman colorectal carcinomaPolymerase chain reaction-based techniquesDukes' BPrognostic factorsColorectal cancerPrimary tumorOverall prevalenceHigh riskPatientsRas mutationsCarcinomaHuman tumorsTumorsDiseasePrevalenceGGT
1988
Interdisciplinary detection of soft tissue sarcomas. Diagnosis, grading and staging.
Leyvraz S, Costa J. Interdisciplinary detection of soft tissue sarcomas. Diagnosis, grading and staging. Die Orthopädie 1988, 17: 121-7. PMID: 3290794.Peer-Reviewed Original ResearchConceptsSoft tissue sarcomasTissue sarcomasDifferent prognostic factorsManagement of patientsStratification of patientsPrognostic factorsSimilar prognosisSurgical marginsHistological diagnosisStaging systemClinical aspectsOptimal diagnosisTumorsPatientsDiagnosisPrognosisSarcomaStagingCliniciansPathologistsGradingThe Pathological Staging of Sarcomas
Costa J, Leyvraz S. The Pathological Staging of Sarcomas. Developments In Oncology 1988, 18-21. DOI: 10.1007/978-94-009-2691-2_4.Peer-Reviewed Original Research
1977
Prognostic Factors in Patients Undergoing Lymphadenectomy of Malignant Melanoma
COHEN A, KETCHAM A, FELIX E, LI S, tOMASZEWSKI M, COSTA J, RABSON A, SIMON R, ROSENBERG S. Prognostic Factors in Patients Undergoing Lymphadenectomy of Malignant Melanoma. Annals Of Surgery 1977, 186: 635-642. PMID: 921357, PMCID: PMC1396308, DOI: 10.1097/00000658-197711000-00016.Peer-Reviewed Original ResearchConceptsNode dissectionLevel of invasionSite of melanomaPositive nodesLymph nodesPrognostic factorsExtremity melanomaMelanoma patientsPrognostic discriminationPreoperative assessmentSame pathologistMalignant melanomaMelanoma thicknessPatientsMelanomaYears' experienceDissectionSurvivalImportant factorInvasionMultivariate evaluationAspatientsFourpatientsPrognosticfactorsThesurgeon