2009
Effects of recombinant human bone morphogenetic protein 2 on surgical infections in a rabbit posterolateral lumbar fusion model.
Miller CP, Simpson AK, Whang PG, Erickson BP, Waked WR, Lawrence JP, Grauer JN. Effects of recombinant human bone morphogenetic protein 2 on surgical infections in a rabbit posterolateral lumbar fusion model. The American Journal Of Orthopedics 2009, 38: 578-84. PMID: 20049353.Peer-Reviewed Original ResearchConceptsLocal infectionRecombinant human bone morphogenetic proteinEarly deathRabbit posterolateral lumbar fusion modelPosterolateral lumbar fusion modelRhBMP-2Postoperative infectionSurgical infectionsSpine surgeryAutograft groupSpinal arthrodesisSterile salineFusion rateAutograftRecombinant human bone morphogenetic protein-2InfectionHuman bone morphogenetic proteinHuman bone morphogenetic protein-2Bone formationProtein 2Staphylococcus aureusRabbitsBone morphogenetic protein-2Bone morphogenetic proteinMorphogenetic protein-2
2007
The Effect of rhBMP-2 on the Incidence and Severity of Postoperative Infections in a Rabbit Posterolateral Lumbar Fusion Model ♦
Miller C, Simpson A, Whang P, Erickson B, Waked W, Lawrence J, Grauer J. The Effect of rhBMP-2 on the Incidence and Severity of Postoperative Infections in a Rabbit Posterolateral Lumbar Fusion Model ♦. Spine: Affiliated Society Meeting Abstracts 2007, &NA;: 38-40. DOI: 10.1097/01.brs.0000317724.54762.b9.Peer-Reviewed Original ResearchRabbit posterolateral lumbar fusion modelPosterolateral lumbar fusion modelPostoperative infectionRhBMP-2
2004
Posterolateral lumbar fusions in athymic rats: characterization of a model
Grauer JN, Bomback DA, Lugo R, Troiano NW, Patel TC, Friedlaender GE. Posterolateral lumbar fusions in athymic rats: characterization of a model. The Spine Journal 2004, 4: 281-286. PMID: 15125850, DOI: 10.1016/j.spinee.2003.10.001.Peer-Reviewed Original ResearchConceptsPosterolateral lumbar fusion modelAthymic ratsManual palpationPosterolateral lumbar fusionL4-L5 levelSmall animal modelsPotential inflammatory responseLumbar fusionInflammatory responseSpinal fusionHistology resultsAutograft fusionAnimal modelsFusion rateOsteoinductive productsRatsIntertransverse fusionPalpationSurvival surgeryGraftWeeksComparison of FusionSpontaneous fusionLimited utilityXenogenic proteins
2001
Osteogenic Protein-1 Overcomes the Inhibitory Effect of Nicotine on Posterolateral Lumbar Fusion
Patel T, Erulkar J, Grauer J, Troiano N, Panjabi M, Friedlaender G. Osteogenic Protein-1 Overcomes the Inhibitory Effect of Nicotine on Posterolateral Lumbar Fusion. Spine 2001, 26: 1656-1661. PMID: 11474350, DOI: 10.1097/00007632-200108010-00004.Peer-Reviewed Original ResearchConceptsPosterolateral lumbar fusionOsteogenic protein-1Inhibitory effectProtein 1Lumbar fusionRabbit posterolateral lumbar fusion modelRabbit posterolateral spine fusion modelFusion massRabbit modelSubcutaneous mini-osmotic pumpsPosterolateral lumbar fusion modelMini-osmotic pumpsNew Zealand white rabbitsNew Zealand white rabbit modelZealand white rabbitsPosterolateral spine fusionSpine fusion modelPosterolateral intertransverse process fusionWhite rabbit modelPresence of nicotineIntertransverse process fusionBone graft alternativesBony fusionBACKGROUND DATASpine fusion