2018
Convergence and Divergence of CRH Amacrine Cells in Mouse Retinal Circuitry
Park SJH, Pottackal J, Ke JB, Jun NY, Rahmani P, Kim IJ, Singer JH, Demb JB. Convergence and Divergence of CRH Amacrine Cells in Mouse Retinal Circuitry. Journal Of Neuroscience 2018, 38: 3753-3766. PMID: 29572434, PMCID: PMC5895998, DOI: 10.1523/jneurosci.2518-17.2018.Peer-Reviewed Original ResearchConceptsAlpha ganglion cellsGanglion cell typesAmacrine cellsGanglion cellsCRH cellsAlpha cellsGABAergic synapsesInhibitory interneuronsExcitation/inhibition balanceCorticotropin-releasing hormoneCre transgenic miceFire action potentialsTonic excitatory driveCell typesBalance of excitationGABA releaseExcitatory circuitsRetinal circuitryExcitatory driveInhibition balanceInhibitory inputsMammalian retinaMouse retinaAction potentialsOptogenetic analyses
2011
Delayed-Rectifier K Channels Contribute to Contrast Adaptation in Mammalian Retinal Ganglion Cells
Weick M, Demb JB. Delayed-Rectifier K Channels Contribute to Contrast Adaptation in Mammalian Retinal Ganglion Cells. Neuron 2011, 71: 166-179. PMID: 21745646, PMCID: PMC3134798, DOI: 10.1016/j.neuron.2011.04.033.Peer-Reviewed Original ResearchConceptsRetinal ganglion cellsGanglion cellsSubsequent depolarizationContrast adaptationOFF alpha ganglion cellsMammalian retinal ganglion cellsAlpha ganglion cellsGuinea pig retinaK channelsSuppress excitabilityPig retinaNa channel inactivationFiring responsesBrief depolarizationBrief hyperpolarizationRectifier K channelsVisual stimulationSomatic membrane patchesChannel inactivationDepolarizationPhysiological rangeIntrinsic mechanismHyperpolarizationCellsSalamander cells