2022
Benefits of weight loss of 10% or more in patients with overweight or obesity: A review
Tahrani AA, Morton J. Benefits of weight loss of 10% or more in patients with overweight or obesity: A review. Obesity 2022, 30: 802-840. PMID: 35333446, DOI: 10.1002/oby.23371.Peer-Reviewed Original ResearchConceptsObesity-related complicationsModest weight lossWeight lossBariatric surgeryLarge weight lossReduced cancer riskWeight-related complicationsCardiovascular risk factorsHealth-related qualityWeight management programType 2 diabetesGreater weight lossMain treatment targetsCost-effective interventionLifestyle modificationLifestyle interventionSevere obesityKnee osteoarthritisSleep apneaRisk factorsCancer riskGlucose metabolismPatientsOverweightTreatment targets
2019
1768-P: Inflammation in Visceral and Subcutaneous Fat and Human Insulin Resistance
MCLAUGHLIN T, ZANLEY E, PETLURA C, TOLENTINO L, CHOI O, CHUANG J, XU Y, MORTON J, ENGLEMAN E. 1768-P: Inflammation in Visceral and Subcutaneous Fat and Human Insulin Resistance. Diabetes 2019, 68 DOI: 10.2337/db19-1768-p.Peer-Reviewed Original ResearchVisceral adipose tissueInsulin resistanceWhole-body insulin sensitivityBariatric surgery patientsImmune cell profilesSystemic insulin resistanceTotal fat massAmerican Heart AssociationPlasma glucose testSystemic glucose metabolismHuman insulin resistanceSurgery patientsInflammation contributesHeart AssociationCytokine releaseImmune cellsInsulin sensitivityMacrophage numbersFat massBacterial antigensAdipocyte stressGlucose testGlucose metabolismHuman studiesAdipose tissue