2001
Physiologic characteristics of canine skeletal muscle: implications for timing skeletal muscle cardiac assist devices
Letsou G, Hogan J, Bsee, Miller C, Elefteriades J, Francischelli D, Baldwin J, Safi H. Physiologic characteristics of canine skeletal muscle: implications for timing skeletal muscle cardiac assist devices. The Annals Of Thoracic Surgery 2001, 72: 1336-1342. PMID: 11603457, DOI: 10.1016/s0003-4975(01)02994-0.Peer-Reviewed Original Research
2000
Right ventricle-sparing heart transplant: promising new technique for recipients with pulmonary hypertension
Elefteriades J, Lovoulos C, Tellides G, Goldstein L, Rocco E, Condos S, Kopf G. Right ventricle-sparing heart transplant: promising new technique for recipients with pulmonary hypertension. The Annals Of Thoracic Surgery 2000, 69: 1858-1863. PMID: 10892937, DOI: 10.1016/s0003-4975(00)01318-7.Peer-Reviewed Original ResearchConceptsRight heart failurePulmonary hypertensionRight heartHeart transplantationHeart failureLeft ventricleOrthotopic heart transplantationSevere pulmonary hypertensionStable sinus rhythmNative aortic valveUnsolved clinical problemPulmonary arterial connectionCardiac transplantationCardiopulmonary bypassArterial connectionsSinus rhythmAortic valveHypertensionClinical problemHeterotopic transplantationTransplantationVentricleEarly causeHeartRecipients
1998
Experimental confirmation of effectiveness of fenestration in acute aortic dissection
Morales D, Quin J, Braxton J, Hammond G, Gusberg R, Elefteriades J. Experimental confirmation of effectiveness of fenestration in acute aortic dissection. The Annals Of Thoracic Surgery 1998, 66: 1679-1683. PMID: 9875771, DOI: 10.1016/s0003-4975(98)00901-1.Peer-Reviewed Original ResearchConceptsRenal arterial flowFemoral blood pressureAortic dissectionBlood pressureAortic fenestrationAortic distensibilityCarotid pressureArterial flowAcute aortic dissectionML/minSubsequent fenestrationOrgan ischemiaRenal flowInfrarenal aortaContinued clinical applicationBlood flowAnimal modelsFenestrationDissectionClinical applicationT-testDistensibilityMinIschemiaAortaDiaphragm pacing.
Elefteriades J, Quin J. Diaphragm pacing. Thoracic Surgery Clinics 1998, 8: 331-57. PMID: 9619308.Peer-Reviewed Original ResearchConceptsPhrenic nerve functionNerve functionUpper motor neuron injuryMotor neuron injuryCareful patient evaluationAdequate psychosocial supportDiaphragm pacingTube complicationsNeuron injuryPatient evaluationPsychosocial supportSuccessful pacingEstablished modePacingElectrode placementDiaphragmComplicationsPatientsInjury
1996
Skeletal Muscle Ventricles in Continuity with the Bloodstream
Ukoha O, Braxton J, Letsou G, Hogan J, Ariyan S, Elefteriades J. Skeletal Muscle Ventricles in Continuity with the Bloodstream. Journal Of Cardiac Surgery 1996, 11: 271-279. PMID: 8902641, DOI: 10.1111/j.1540-8191.1996.tb00050.x.Peer-Reviewed Original ResearchConceptsAverage systolic pressureDegree of augmentationSystolic pressureDiastolic augmentationBlood flowCanine modelEnd-stage congestive heart failureOutflow conduitIntra-aortic balloon pumpStimulation delayCongestive heart failureLatissimus dorsi muscleSkeletal muscle ventriclesSMV ruptureSMV stimulationThoracodorsal nerveTiming of stimulationArterial pressureRespiratory insufficiencyBalloon pumpHeart failureProlonged anticoagulationValved conduitIntraoperative instabilityProsthetic valves
1995
Dynamic Cardiomyoplasty
Letsou G, Austin L, Grandjean P, Braxton J, Elefteriades J. Dynamic Cardiomyoplasty. Cardiology Clinics 1995, 13: 121-124. PMID: 7796426, DOI: 10.1016/s0733-8651(18)30068-7.Peer-Reviewed Original ResearchConceptsSystolic performanceNYHA class III heart failureClass III heart failureProgressive left ventricular dilatationLeft ventricular dilatationRandomized clinical trialsMechanism of actionOperative riskSymptomatic improvementHeart failureVentricular dilatationDynamic cardiomyoplastyClinical trialsObjective improvementSurvival advantageLeft ventriclePromising new techniqueDefinitive answerPatientsCardiomyoplastyDilatationVentricleTrialsSkeletal Muscle for Cardiac Assist
Letsou G, Braxton J, Elefteriades J, Ariyan S. Skeletal Muscle for Cardiac Assist. Cardiology Clinics 1995, 13: 125-135. PMID: 7796427, DOI: 10.1016/s0733-8651(18)30069-9.Peer-Reviewed Original Research
1994
Latency of Skeletal Muscle Contraction after Pulse Train Stimulation: An Important Factor in Correct Timing of Skeletal Muscle Cardiac Assist Devices
Letsou G, Zarif A, Smith A, Hogan J, Lee P, Ariyan S, Baldwin J, Elefteriades J. Latency of Skeletal Muscle Contraction after Pulse Train Stimulation: An Important Factor in Correct Timing of Skeletal Muscle Cardiac Assist Devices. Journal Of Surgical Research 1994, 57: 672-676. PMID: 7996844, DOI: 10.1006/jsre.1994.1199.Peer-Reviewed Original ResearchConceptsPeak tensionSkeletal muscle contractionSkeletal muscleAssist deviceEnd-stage cardiac failureMuscle contractionCanine latissimus dorsi musclePulse train stimulationLatissimus dorsi muscleCanine heart rateContraction/relaxation cycleCardiac assist devicesCardiac augmentationConditioning regimensCardiac failureTrain stimulationHeart rateCardiac assistanceContraction timingOptimal timingMuscleDorsi muscleCardiac cycleContractionCorrect timing
1992
Comparison of 180-degree and 360-degree skeletal muscle nerve cuff electrodes
Letsou G, Hogan J, Lee P, Kim J, Ariyan S, Dewar M, Baldwin J, Elefteriades J. Comparison of 180-degree and 360-degree skeletal muscle nerve cuff electrodes. The Annals Of Thoracic Surgery 1992, 54: 925-931. PMID: 1417288, DOI: 10.1016/0003-4975(92)90651-j.Peer-Reviewed Original ResearchConceptsNerve cuff electrodesThoracodorsal nerveCuff electrodeLatissimus dorsiEnd-stage cardiac failureNearby nerve fibersSkeletal muscleLatissimus dorsi muscleSkeletal muscle stimulationCardiac augmentationCardiac failureAcute evaluationHistologic characteristicsHistologic examinationNerve fibersClinical practiceI fibersMuscle stimulationNerveElectrode stimulationMuscle fibersMuscleMonthsSignificant differencesStimulation