1978
Afferent projections to the rat locus coeruleus as determined by a retrograde tracing technique
Cedarbaum J, Aghajanian G. Afferent projections to the rat locus coeruleus as determined by a retrograde tracing technique. The Journal Of Comparative Neurology 1978, 178: 1-15. PMID: 632368, DOI: 10.1002/cne.901780102.Peer-Reviewed Original ResearchConceptsLocus coeruleusRat locus coeruleusCentral gray substanceLateral hypothalamic areaRetrograde tracing techniquesLateral reticular nucleusCatecholamine cell groups A1Magnocellular preoptic areaSingle-cell recordingsDorsal hornReactive neuronsNoradrenergic neuronsSolitary tractAfferent innervationLabeled neuronsHypothalamic areaReticular nucleusHRP injectionsPreoptic areaSpinal cordInsular cortexAfferent projectionsGray substanceReticular formationAfferent connections
1977
Catecholamine receptors on locus coeruleus neurons: Pharmacological characterization
Cedarbaum J, Aghajanian G. Catecholamine receptors on locus coeruleus neurons: Pharmacological characterization. European Journal Of Pharmacology 1977, 44: 375-385. PMID: 330174, DOI: 10.1016/0014-2999(77)90312-0.Peer-Reviewed Original ResearchConceptsLC neuronsLocus coeruleusNoradrenergic neuronsCatecholamine receptorsΑ-receptorsCell bodiesΑ-methylnorepinephrinePostsynaptic α-receptorsPeripheral sympathetic nervesLocus coeruleus neuronsDopamine agonist apomorphineCentral dopamine receptorsΒ-agonist isoproterenolSingle-unit recordingsSympathetic nervesAgonist apomorphineAgonist clonidineMicroiontophoretic applicationCoeruleus neuronsSpontaneous firingΑ-adrenoreceptorsDopamine receptorsPharmacological characterizationAgonist drugsPharmacological characteristics
1976
Noradrenergic neurons of the locus coeruleus: inhibition by epinephrine and activation by the α-antagonist piperoxane
Cedarbaum J, Aghajanian G. Noradrenergic neurons of the locus coeruleus: inhibition by epinephrine and activation by the α-antagonist piperoxane. Brain Research 1976, 112: 413-419. PMID: 8191, DOI: 10.1016/0006-8993(76)90297-3.Peer-Reviewed Original Research