1990
General assay for phosphoproteins in cerebrospinal fluid: A candidate market for paraneoplastic cerebellar degeneration
Gandy S, Grebb J, Rosen N, Albert K, Devinsky O, Blumberg H, Anderson N, Cedarbaum J, Porter R, Sedvall G, Posner J, Greengard P. General assay for phosphoproteins in cerebrospinal fluid: A candidate market for paraneoplastic cerebellar degeneration. Annals Of Neurology 1990, 28: 829-833. PMID: 2285268, DOI: 10.1002/ana.410280616.Peer-Reviewed Original ResearchConceptsProtein kinase C substrate proteinProtein kinase substratesProtein phosphorylation systemsSubstrate proteinsKinase substratePhosphorylation systemBiochemical characterizationCell typesPhosphoproteinNeuronal cellsNeuronal diseasesNeuronal enrichmentGeneral assayUnique markerPotential insightsNeuronal populationsProteinNeurological diseasesCerebellar degenerationCellsAssaysEnrichmentAssay techniquesKdMarkers
1986
Mitochondrial dysfunction and spinocerebellar degenerations
Cedarbaum J, Blass J. Mitochondrial dysfunction and spinocerebellar degenerations. Journal Of Molecular Neuroscience 1986, 4: 43-63. PMID: 3520401, DOI: 10.1007/bf02834298.Peer-Reviewed Original ResearchMeSH KeywordsAtaxiaBrainCerebellar AtaxiaCerebellar DiseasesHumansMagnetic Resonance SpectroscopyMitochondriaNerve DegenerationSpinal Cord DiseasesConceptsSpinocerebellar degenerationProminent clinical featureMitochondrial damageMultiple system degenerationClinical featuresPathophysiological mechanismsOlivopontocerebellar atrophyDiffuse diseaseSystem degenerationNervous systemRelated disordersLong axonsObserved pathologyAtaxiaDegenerationMitochondrial dysfunctionSimplified classificationFriedreich's ataxiaCommon mechanism